Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE/cglE   Type   Machinery gene
Locus tag   FOB92_RS00845 Genome accession   NZ_CP046335
Coordinates   179082..179384 (+) Length   100 a.a.
NCBI ID   WP_045597458.1    Uniprot ID   -
Organism   Streptococcus mitis strain FDAARGOS_684     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 174082..184384
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FOB92_RS00815 (FOB92_00815) - 174843..175901 (+) 1059 WP_000649460.1 zinc-dependent alcohol dehydrogenase family protein -
  FOB92_RS00820 (FOB92_00820) - 176051..176416 (+) 366 WP_000286405.1 DUF1033 family protein -
  FOB92_RS00825 (FOB92_00825) comGA/cglA/cilD 176492..177433 (+) 942 WP_000249545.1 competence type IV pilus ATPase ComGA Machinery gene
  FOB92_RS00830 (FOB92_00830) comGB/cglB 177381..178397 (+) 1017 WP_004238896.1 competence type IV pilus assembly protein ComGB Machinery gene
  FOB92_RS00835 (FOB92_00835) comGC/cglC 178399..178722 (+) 324 WP_000738641.1 comG operon protein ComGC Machinery gene
  FOB92_RS00840 (FOB92_00840) comGD/cglD 178685..179119 (+) 435 WP_029689647.1 competence type IV pilus minor pilin ComGD Machinery gene
  FOB92_RS00845 (FOB92_00845) comGE/cglE 179082..179384 (+) 303 WP_045597458.1 competence type IV pilus minor pilin ComGE Machinery gene
  FOB92_RS00850 (FOB92_00850) comGF/cglF 179347..179808 (+) 462 WP_000250509.1 competence type IV pilus minor pilin ComGF Machinery gene
  FOB92_RS00855 (FOB92_00855) comGG/cglG 179786..180199 (+) 414 WP_000265657.1 competence type IV pilus minor pilin ComGG Machinery gene
  FOB92_RS00860 (FOB92_00860) - 180232..180819 (+) 588 WP_000679792.1 class I SAM-dependent methyltransferase -
  FOB92_RS00865 (FOB92_00865) comYH 180880..181833 (+) 954 WP_000345104.1 class I SAM-dependent methyltransferase Machinery gene
  FOB92_RS00870 (FOB92_00870) - 181883..183073 (+) 1191 WP_000167778.1 acetate kinase -
  FOB92_RS00875 (FOB92_00875) rnpA 183223..183594 (+) 372 WP_000739243.1 ribonuclease P protein component -

Sequence

Protein


Download         Length: 100 a.a.        Molecular weight: 11149.14 Da        Isoelectric Point: 9.7273

>NTDB_id=402777 FOB92_RS00845 WP_045597458.1 179082..179384(+) (comGE/cglE) [Streptococcus mitis strain FDAARGOS_684]
MEKLNALRKQKIRAVILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEILRVAKMALQTGQNQVNINGVEIQVFS
SEKGLEVYHGSEQLLAIKEP

Nucleotide


Download         Length: 303 bp        

>NTDB_id=402777 FOB92_RS00845 WP_045597458.1 179082..179384(+) (comGE/cglE) [Streptococcus mitis strain FDAARGOS_684]
ATGGAAAAATTAAACGCATTAAGGAAACAAAAGATTAGGGCAGTGATTTTACTGGAAGCAGTAGTCGCTTTAGCTATCTT
TGCCAGCATTGCGACCCTTCTTTTGGGACAAATTCAGAAAAATAGGCAGGAAGAAGCAAAAATCTTGCAGAAAGAAGAGA
TCTTGCGTGTAGCTAAGATGGCCTTGCAGACAGGTCAAAATCAGGTAAACATCAACGGAGTTGAGATTCAGGTGTTTTCT
AGTGAAAAGGGATTGGAGGTCTACCATGGTTCAGAACAGTTGTTGGCTATCAAAGAGCCATAA

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(16-97)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE/cglE Streptococcus mitis NCTC 12261

100

100

1
  comGE/cglE Streptococcus mitis SK321

99

100

0.99
  comGE/cglE Streptococcus pneumoniae Rx1

98

100

0.98
  comGE/cglE Streptococcus pneumoniae D39

98

100

0.98
  comGE/cglE Streptococcus pneumoniae R6

98

100

0.98
  comGE/cglE Streptococcus pneumoniae TIGR4

98

100

0.98
  comYE Streptococcus mutans UA140

44.444

90

0.4
  comYE Streptococcus mutans UA159

44.444

90

0.4

Multiple sequence alignment