Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   HUZ76_RS03555 Genome accession   NZ_CP055022
Coordinates   746492..747151 (-) Length   219 a.a.
NCBI ID   WP_033560344.1    Uniprot ID   -
Organism   Escherichia coli strain SWHEFF_68     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 741492..752151
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HUZ76_RS03525 (HUZ76_03480) - 741608..742555 (+) 948 WP_001305106.1 iron-siderophore ABC transporter substrate-binding protein -
  HUZ76_RS03530 (HUZ76_03485) - 742552..743439 (+) 888 WP_033560346.1 MurR/RpiR family transcriptional regulator -
  HUZ76_RS03535 (HUZ76_03490) ygiN 743484..743798 (-) 315 WP_000633738.1 putative quinol monooxygenase -
  HUZ76_RS03540 (HUZ76_03495) mdaB 743829..744410 (-) 582 WP_000065430.1 NADPH:quinone oxidoreductase MdaB -
  HUZ76_RS03545 (HUZ76_03500) ygiZ 744768..745100 (+) 333 WP_219372263.1 DUF2645 family protein -
  HUZ76_RS03550 (HUZ76_03505) qseC 745146..746495 (-) 1350 WP_000673339.1 quorum sensing histidine kinase QseC -
  HUZ76_RS03555 (HUZ76_03510) ciaR 746492..747151 (-) 660 WP_033560344.1 quorum sensing response regulator transcription factor QseB Regulator
  HUZ76_RS03560 (HUZ76_03515) ygiW 747303..747695 (+) 393 WP_000712658.1 OB fold stress tolerance protein YgiW -
  HUZ76_RS03565 (HUZ76_03520) ygiV 747748..748230 (+) 483 WP_000183507.1 GyrI-like domain-containing protein -
  HUZ76_RS03570 (HUZ76_03525) ygiS 748339..749946 (+) 1608 WP_033560343.1 ABC transporter substrate-binding protein -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24673.60 Da        Isoelectric Point: 6.9850

>NTDB_id=402547 HUZ76_RS03555 WP_033560344.1 746492..747151(-) (ciaR) [Escherichia coli strain SWHEFF_68]
MRILLIEDDMLIGDGIKTGLSKMGFSVDWFTQGRQGKEALYSAPYDAVVLDLTLPGMDGRDILREWREKGQREPVLILTA
RDALAERVEGLRLGADDYLCKPFALIEVAARLEALMRRTNGQASNELRHGNVMLDPGKRIATLAGEPLTLKPKEFALLEL
LMRNAGRVLPRKLIEEKLYTWDEEVTSNAVEVHVHHLRRKLGSDFIRTVHGIGYTLGEK

Nucleotide


Download         Length: 660 bp        

>NTDB_id=402547 HUZ76_RS03555 WP_033560344.1 746492..747151(-) (ciaR) [Escherichia coli strain SWHEFF_68]
ATGCGAATTTTACTGATCGAAGATGACATGCTGATTGGCGACGGCATCAAAACGGGCCTTAGTAAAATGGGTTTTAGCGT
CGACTGGTTTACACAAGGTCGTCAGGGAAAAGAGGCGCTATATAGCGCACCTTATGATGCGGTGGTCCTGGATTTAACCT
TACCGGGCATGGATGGTCGCGATATTTTGCGCGAATGGCGAGAAAAAGGTCAGCGTGAGCCGGTTTTGATCCTGACCGCG
CGCGATGCGCTGGCGGAACGTGTAGAAGGGCTGCGTCTGGGAGCTGACGATTATCTGTGTAAACCTTTTGCGTTGATAGA
AGTCGCCGCCAGGCTGGAAGCTCTGATGCGCCGAACCAACGGCCAGGCCAGCAACGAGCTGCGCCACGGCAACGTCATGC
TCGACCCCGGCAAACGTATCGCCACGCTGGCTGGCGAACCCTTAACGCTGAAACCAAAAGAATTTGCCCTGCTGGAATTA
CTGATGCGTAACGCTGGTCGGGTACTGCCGCGCAAACTGATTGAAGAGAAACTGTATACCTGGGACGAAGAGGTCACCAG
TAATGCCGTTGAAGTGCATGTGCATCATCTGCGACGCAAACTCGGCAGTGATTTTATTCGTACCGTTCATGGTATTGGCT
ACACATTAGGTGAGAAATGA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-216)

Response regulator receiver domain (Response_reg)

(3-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

38.326

100

0.397
  ciaR Streptococcus pneumoniae D39

38.326

100

0.397
  ciaR Streptococcus pneumoniae R6

38.326

100

0.397
  ciaR Streptococcus pneumoniae TIGR4

38.326

100

0.397
  ciaR Streptococcus mutans UA159

35.874

100

0.365

Multiple sequence alignment