Detailed information NTG0040240

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: SALIVA_RS00320
• Genome accession: NC_017595
• Coordinates: 54897..57428 (+)
• Length: 843 a.a.
• NCBI ID: WP_371748909.1
• Uniprot ID: -
• Organism: Streptococcus salivarius JIM8777
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 49897..62428

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SALIVA_RS00300 (SALIVA_0058)	purB	50070..51368 (+)	1299	WP_002948159.1	adenylosuccinate lyase	-
SALIVA_RS00305 (SALIVA_0059)	argS	52244..53935 (-)	1692	WP_014633771.1	arginine--tRNA ligase	-
SALIVA_RS00310 (SALIVA_0060)	argR	54090..54518 (+)	429	WP_171963651.1	arginine repressor	-
SALIVA_RS00315 (SALIVA_0061)	-	54518..54877 (+)	360	WP_002889586.1	YlbF family regulator	-
SALIVA_RS00320 (SALIVA_0062)	hexA	54897..57428 (+)	2532	WP_371748909.1	DNA mismatch repair protein MutS	Machinery gene
SALIVA_RS00325 (SALIVA_0063)	-	57462..57917 (-)	456	WP_014633774.1	DUF3021 domain-containing protein	-
SALIVA_RS00330 (SALIVA_0064)	brsR	57914..58351 (-)	438	WP_014633775.1	LytTR family DNA-binding domain-containing protein	Regulator
SALIVA_RS00335 (SALIVA_0065)	-	58530..58835 (+)	306	WP_002886319.1	hypothetical protein	-
SALIVA_RS00340 (SALIVA_0066)	hexB	58885..60828 (+)	1944	WP_014633776.1	DNA mismatch repair endonuclease MutL	Machinery gene
SALIVA_RS00345 (SALIVA_0067)	-	60959..61180 (+)	222	WP_002886321.1	hypothetical protein	-
SALIVA_RS00350 (SALIVA_0068)	ruvA	61338..61928 (+)	591	WP_002886323.1	Holliday junction branch migration protein RuvA	Machinery gene

Sequence

Protein

• Length: 843 a.a.
• Molecular weight: 94638.72 Da
• Isoelectric Point: 4.6363

>NTDB_id=40240 SALIVA_RS00320 WP_371748909.1 54897..57428(+) (hexA) [Streptococcus salivarius JIM8777]
MQQYLDIKENYPDAFLLFRMGDFYELFYDDAVKAAQILEISLTSRNKNADNPIPMAGVPYHSAQSYIDVLVEMGYKVAIA
EQMEDPKQAVGVVKREVVQVITPGTVVDSSKPDNANNFLVAIDKAGSRFGLAYMDVSTGEFFATELDDFSSVCSEIQNLK
AREVVVGYDLPEADEQVLVKQLNLLLSKETEVYDDVHLIDTSLTDLESSVAGKLLQYVHRTQMRELSHLQKAQHYEIKDY
LQMSYATKSSLDLLENARTGKKHGSLFWLLDETKTAMGMRLLRTWIDRPLVNQAAIMERQNIIQVFLDNFFERSDLTESL
KGVYDIERLASRVSFGKANPKDLIQLGHTLAQVPVIKAILESFDDEALSRLLQELDALPELESLIRSAIDPDAPATITEG
GIIRAGFDETLDKYRKVMSEGTSWIADIEAKEREASGIATLKIDYNRKDGYYFHVTNSNLSLVPDHFFRKATLKNSERFG
TAELAKIEGEMLEAREKSSTLEYDIFMRVREQVERYIDRLQSLAKAIATVDVLQSLAVIAETNHYVRPVFNDEHRIVIDQ
GRHAVVEKVMGVQEYIPNTITFDSQTNVQLITGPNMSGKSTYMRQLALSVVMAQMGSYVPADSIDLPVFDAIYTRIGAAD
DLISGQSTFMVEMMEANQAIKRATLNSLIIFDELGRGTATYDGMALAQSIIEFIHDKVGAKTMFATHYHELTALSNTLTH
LVNVHVATLEKDGEVTFLHKIVDGPADKSYGIHVAKIAGLPADLLERADTILTQLEGETVTIRPQEKVSPQEKPATETHV
NEQISLFDDFTENPVLQELRDLDIYNMTPMQVMMAVADLKQKL

Nucleotide

• Length: 2532 bp

>NTDB_id=40240 SALIVA_RS00320 WP_371748909.1 54897..57428(+) (hexA) [Streptococcus salivarius JIM8777]
ATGCAGCAGTATTTGGATATCAAGGAAAATTATCCAGATGCTTTTTTGCTCTTCCGTATGGGTGATTTTTACGAATTATT
TTATGATGATGCCGTTAAGGCTGCCCAGATTTTGGAAATTAGCCTAACCAGTCGTAATAAGAACGCCGATAATCCCATTC
CTATGGCTGGTGTTCCTTACCATTCAGCTCAATCTTATATTGATGTCTTGGTTGAGATGGGCTACAAGGTAGCCATTGCT
GAGCAGATGGAGGATCCTAAACAGGCTGTTGGTGTGGTTAAGCGTGAGGTGGTTCAGGTTATCACGCCAGGGACAGTGGT
TGACAGTTCTAAACCTGATAATGCCAACAATTTCTTGGTAGCCATTGACAAGGCTGGAAGTCGTTTTGGTCTGGCCTATA
TGGATGTGTCAACGGGTGAATTTTTTGCGACAGAGTTGGACGATTTCAGTTCAGTTTGTAGTGAAATTCAGAACCTTAAG
GCACGTGAAGTAGTAGTTGGTTATGATTTACCTGAAGCTGATGAACAAGTTTTGGTGAAGCAACTCAACCTTCTACTTTC
CAAGGAAACAGAGGTTTACGATGATGTCCACTTGATTGACACTAGCTTGACAGACTTGGAAAGCAGTGTAGCGGGTAAAC
TTCTCCAGTATGTGCACCGTACTCAGATGCGCGAGCTTAGCCATTTACAAAAGGCTCAGCACTATGAGATTAAGGATTAC
TTGCAGATGTCCTATGCAACCAAGTCAAGTTTGGATTTGTTGGAAAATGCTAGAACAGGTAAGAAACACGGTTCTCTTTT
CTGGCTCTTGGATGAAACCAAGACAGCTATGGGGATGCGTCTCTTGCGTACTTGGATTGACCGTCCTTTAGTGAATCAGG
CTGCCATCATGGAGCGCCAGAATATTATCCAAGTTTTCTTGGACAATTTCTTCGAGCGTAGTGATCTGACTGAGAGTCTT
AAAGGGGTTTACGATATTGAGCGACTGGCCAGTCGTGTTTCCTTTGGAAAGGCTAATCCTAAAGATTTGATTCAGCTAGG
TCATACCCTAGCTCAGGTTCCAGTTATTAAGGCGATTTTGGAGTCTTTTGATGACGAGGCCTTGTCACGTCTTTTACAAG
AGCTAGATGCTCTGCCAGAATTAGAGAGTCTGATTCGGTCGGCTATTGATCCCGATGCTCCAGCAACCATTACAGAAGGT
GGTATTATCCGTGCTGGTTTTGATGAGACCTTGGACAAGTATCGCAAGGTGATGAGCGAGGGGACGTCATGGATCGCAGA
CATCGAAGCCAAGGAACGTGAAGCGTCTGGTATTGCAACACTAAAAATTGATTATAACCGTAAAGATGGTTATTACTTCC
ATGTGACCAACTCTAACCTTAGCTTGGTTCCTGACCATTTCTTCCGCAAGGCAACCCTGAAAAACTCAGAGCGTTTTGGA
ACTGCCGAGTTGGCTAAGATTGAAGGTGAGATGCTTGAGGCACGTGAAAAGTCATCAACGCTAGAGTATGATATTTTCAT
GCGTGTCCGTGAGCAGGTTGAACGCTATATTGACCGTTTGCAATCTTTGGCTAAGGCTATTGCGACAGTCGATGTGCTTC
AGAGTTTGGCTGTTATAGCAGAGACTAATCATTATGTTCGTCCTGTGTTCAATGATGAACATCGTATCGTTATTGATCAA
GGTCGTCATGCGGTGGTTGAGAAGGTTATGGGTGTTCAGGAATACATTCCAAACACGATTACCTTTGACAGTCAGACCAA
TGTTCAGCTCATTACTGGGCCAAATATGAGTGGTAAATCTACTTATATGCGTCAGTTGGCCTTGTCAGTCGTTATGGCTC
AGATGGGGTCTTATGTGCCAGCAGATAGTATTGATTTGCCAGTTTTTGACGCCATCTATACACGTATTGGTGCTGCAGAT
GACTTGATTTCAGGTCAGTCAACCTTCATGGTTGAGATGATGGAGGCTAACCAGGCAATTAAACGGGCAACACTTAATTC
CTTGATTATTTTTGATGAGTTGGGGCGTGGAACAGCCACCTACGATGGTATGGCTTTGGCCCAGTCTATCATTGAGTTTA
TTCATGACAAGGTTGGGGCTAAAACCATGTTTGCTACCCATTATCATGAGTTGACAGCCCTGTCAAATACTTTGACACAC
CTTGTCAACGTTCATGTGGCGACACTTGAAAAGGACGGAGAGGTGACTTTCCTTCACAAGATTGTCGATGGCCCAGCCGA
TAAATCTTATGGTATTCATGTGGCTAAGATTGCAGGTTTACCAGCAGATTTACTGGAACGTGCTGACACCATCTTGACAC
AATTAGAGGGCGAGACAGTTACCATCCGACCTCAGGAAAAGGTATCGCCTCAAGAGAAGCCAGCCACTGAAACACATGTC
AACGAGCAAATCTCTCTCTTTGATGATTTTACTGAAAATCCGGTTCTTCAAGAGTTACGTGATTTGGACATTTACAATAT
GACACCGATGCAGGTCATGATGGCTGTAGCGGATTTAAAACAGAAACTATAA

Domains

Predicted by InterProScan.

• MutS domain I (MutS_I) (1-109)

• MutS family domain IV (MutS_IV) (406-496)

• MutS domain III (MutS_III) (247-537)

• MutS domain II (MutS_II) (117-230)

• MutS domain V (MutS_V) (590-776)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	73.934	100	0.74
mutS	Pseudomonas stutzeri strain ATCC 17587	36.427	100	0.372