Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   HUZ63_RS03595 Genome accession   NZ_CP054965
Coordinates   726743..727402 (-) Length   219 a.a.
NCBI ID   WP_001221493.1    Uniprot ID   Q3YXL4
Organism   Escherichia coli strain STIN_95     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 721743..732402
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HUZ63_RS03565 (HUZ63_03520) ygiN 722644..722958 (-) 315 WP_000633738.1 putative quinol monooxygenase -
  HUZ63_RS03570 (HUZ63_03525) mdaB 722989..723570 (-) 582 WP_000065430.1 NADPH:quinone oxidoreductase MdaB -
  HUZ63_RS03575 - 723820..724299 (+) 480 WP_000065329.1 Hcp family type VI secretion system effector -
  HUZ63_RS03580 - 724302..725012 (+) 711 WP_000834024.1 hypothetical protein -
  HUZ63_RS03585 (HUZ63_03535) ygiZ 725019..725351 (+) 333 WP_000914696.1 DUF2645 family protein -
  HUZ63_RS03590 (HUZ63_03540) qseC 725397..726746 (-) 1350 WP_000673367.1 quorum sensing histidine kinase QseC -
  HUZ63_RS03595 (HUZ63_03545) ciaR 726743..727402 (-) 660 WP_001221493.1 quorum sensing response regulator transcription factor QseB Regulator
  HUZ63_RS03600 (HUZ63_03550) ygiW 727554..727946 (+) 393 WP_000712658.1 OB fold stress tolerance protein YgiW -
  HUZ63_RS03605 (HUZ63_03555) ygiV 727999..728481 (+) 483 WP_000183508.1 GyrI-like domain-containing protein -
  HUZ63_RS03610 (HUZ63_03560) ygiS 728590..730197 (+) 1608 WP_001350460.1 ABC transporter substrate-binding protein -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24687.63 Da        Isoelectric Point: 6.9850

>NTDB_id=402380 HUZ63_RS03595 WP_001221493.1 726743..727402(-) (ciaR) [Escherichia coli strain STIN_95]
MRILLIEDDMLIGDGIKTGLSKMGFSVDWFTQGRQGKEALYSAPYDAVILDLTLPGMDGRDILREWREKGQREPVLILTA
RDALAERVEGLRLGADDYLCKPFALIEVAARLEALMRRTNGQASNELRHGNVMLDPGKRIATLAGEPLTLKPKEFALLEL
LMRNAGRVLPRKLIEEKLYTWDEEVTSNAVEVHVHHLRRKLGSDFIRTVHGIGYTLGEK

Nucleotide


Download         Length: 660 bp        

>NTDB_id=402380 HUZ63_RS03595 WP_001221493.1 726743..727402(-) (ciaR) [Escherichia coli strain STIN_95]
ATGCGAATTTTACTGATAGAAGATGACATGCTGATTGGCGACGGCATCAAAACGGGCCTTAGTAAAATGGGTTTTAGCGT
CGACTGGTTTACACAAGGTCGTCAGGGAAAAGAAGCGCTATATAGCGCGCCTTATGATGCGGTGATCCTGGATTTAACCT
TACCGGGCATGGATGGTCGCGATATTTTGCGCGAATGGCGAGAAAAAGGTCAGCGTGAGCCGGTATTGATCCTGACTGCG
CGCGATGCGCTGGCGGAACGTGTAGAAGGGCTGCGTCTGGGAGCTGACGATTATCTGTGTAAACCTTTTGCGTTGATAGA
AGTCGCCGCCAGGCTGGAAGCTCTGATGCGCCGAACCAACGGCCAGGCCAGCAACGAGCTGCGCCACGGCAACGTCATGC
TAGACCCTGGCAAACGTATCGCCACGCTGGCTGGCGAACCCTTAACGCTGAAACCAAAAGAATTTGCCCTGCTGGAATTA
CTGATGCGTAACGCTGGTCGGGTACTGCCGCGCAAACTGATTGAAGAGAAACTGTATACCTGGGACGAAGAGGTCACCAG
TAATGCCGTTGAAGTGCATGTGCATCATCTGCGACGCAAACTCGGTAGTGATTTTATTCGTACCGTGCATGGTATTGGCT
ACACATTAGGTGAGAAATGA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-216)

Response regulator receiver domain (Response_reg)

(3-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3YXL4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

38.326

100

0.397
  ciaR Streptococcus pneumoniae D39

38.326

100

0.397
  ciaR Streptococcus pneumoniae R6

38.326

100

0.397
  ciaR Streptococcus pneumoniae TIGR4

38.326

100

0.397
  ciaR Streptococcus mutans UA159

35.874

100

0.365