Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   GMB29_RS22810 Genome accession   NZ_CP046266
Coordinates   4727769..4728410 (-) Length   213 a.a.
NCBI ID   WP_136352624.1    Uniprot ID   A0A4S4C0C7
Organism   Metabacillus sediminilitoris strain DSL-17     
Function   promoting transcription of comS (predicted from homology)   
Competence regulation

Genomic Context

Location: 4722769..4733410
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GMB29_RS22775 (GMB29_22775) - 4723923..4724360 (+) 438 WP_227551415.1 Na(+)/H(+) antiporter subunit B -
  GMB29_RS22780 (GMB29_22780) - 4724361..4724699 (+) 339 WP_136352629.1 Na(+)/H(+) antiporter subunit C -
  GMB29_RS22785 (GMB29_22785) - 4724692..4726173 (+) 1482 WP_136352628.1 Na+/H+ antiporter subunit D -
  GMB29_RS22790 (GMB29_22790) - 4726179..4726655 (+) 477 WP_136352627.1 Na+/H+ antiporter subunit E -
  GMB29_RS22795 (GMB29_22795) - 4726655..4726939 (+) 285 WP_136352626.1 Na(+)/H(+) antiporter subunit F1 -
  GMB29_RS22800 (GMB29_22800) mnhG 4726923..4727285 (+) 363 WP_136352625.1 monovalent cation/H(+) antiporter subunit G -
  GMB29_RS22805 (GMB29_22805) - 4727351..4727740 (-) 390 WP_196305204.1 hotdog fold thioesterase -
  GMB29_RS22810 (GMB29_22810) comA 4727769..4728410 (-) 642 WP_136352624.1 response regulator transcription factor Regulator
  GMB29_RS22815 (GMB29_22815) comP 4728518..4730818 (-) 2301 WP_136352623.1 sensor histidine kinase Regulator
  GMB29_RS22820 (GMB29_22820) comX 4730841..4730999 (-) 159 WP_136352622.1 competence pheromone ComX -
  GMB29_RS22825 (GMB29_22825) - 4731002..4731943 (-) 942 WP_136352621.1 polyprenyl synthetase family protein -
  GMB29_RS22830 (GMB29_22830) - 4732321..4732461 (-) 141 WP_136352620.1 DegQ family regulator -
  GMB29_RS22835 (GMB29_22835) - 4732822..4733046 (-) 225 WP_136352619.1 hypothetical protein -

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 24086.54 Da        Isoelectric Point: 4.9930

>NTDB_id=402104 GMB29_RS22810 WP_136352624.1 4727769..4728410(-) (comA) [Metabacillus sediminilitoris strain DSL-17]
MIHILVVDDHPAVREGTKAILEAEPGIKVDCLDPPYTVEAINNIDLSPFDVILMDLNLGDINGMEISKTVIHKNHSCKII
LYTGYDVWDYFDEAIRIGIHGAVSKTESKKKLLTYIHHAIEGDIVVPYQYFKNLLSQKQAEMIETNSDRQDFNEREKAIL
QEVEKGLTNQEIADHLHLSKRSIEYSLTAIFNKLNVSTRTEAVLIAKAEGIID

Nucleotide


Download         Length: 642 bp        

>NTDB_id=402104 GMB29_RS22810 WP_136352624.1 4727769..4728410(-) (comA) [Metabacillus sediminilitoris strain DSL-17]
ATGATACATATTTTAGTCGTAGATGATCATCCAGCAGTTCGAGAAGGTACAAAAGCAATACTTGAGGCTGAGCCAGGGAT
TAAGGTTGATTGCTTAGATCCTCCATATACTGTTGAAGCAATAAATAATATTGACTTATCACCATTTGATGTGATTTTAA
TGGATTTAAACTTAGGTGATATAAATGGGATGGAAATATCGAAAACAGTCATACATAAGAATCACTCTTGTAAAATCATT
CTATACACTGGATATGATGTTTGGGATTATTTCGATGAAGCCATTCGAATTGGTATCCATGGAGCTGTTAGTAAGACAGA
ATCAAAAAAGAAACTATTAACCTATATTCACCATGCAATTGAAGGTGACATTGTAGTACCGTATCAATATTTTAAAAATC
TGCTTAGTCAGAAACAAGCGGAAATGATTGAAACAAATTCGGACCGACAAGACTTTAATGAACGTGAAAAAGCGATCTTG
CAAGAAGTTGAAAAGGGACTGACAAATCAGGAAATTGCCGATCATCTTCATCTAAGCAAAAGGTCGATTGAATATAGCTT
AACAGCGATATTTAATAAGCTAAATGTTAGTACGCGTACAGAAGCAGTTCTTATTGCAAAAGCAGAAGGAATCATTGATT
AA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-116)

Bacterial regulatory proteins, luxR family (GerE)

(153-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A4S4C0C7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Bacillus subtilis subsp. subtilis str. 168

59.813

100

0.601

Multiple sequence alignment