Detailed information NTG0040177

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: SOR_RS01150
• Genome accession: NC_015291
• Coordinates: 218590..219600 (+)
• Length: 336 a.a.
• NCBI ID: WP_001090635.1
• Uniprot ID: I0Q241
• Organism: Streptococcus oralis Uo5
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 213590..224600

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SOR_RS01125 (SOR_0227)	-	213903..215225 (+)	1323	WP_001002852.1	bifunctional folylpolyglutamate synthase/dihydrofolate synthase	-
SOR_RS01130 (SOR_0228)	folE	215206..215760 (+)	555	WP_000380932.1	GTP cyclohydrolase I FolE	-
SOR_RS01135 (SOR_0229)	folK	215919..216740 (+)	822	WP_000372521.1	2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase	-
SOR_RS01140 (SOR_0230)	-	216733..218016 (+)	1284	WP_001125363.1	hypothetical protein	-
SOR_RS01145 (SOR_0231)	-	218068..218385 (-)	318	WP_000886045.1	DUF960 domain-containing protein	-
SOR_RS01150 (SOR_0232)	ccpA	218590..219600 (+)	1011	WP_001090635.1	catabolite control protein A	Regulator
SOR_RS01155 (SOR_0233)	-	219654..220616 (-)	963	WP_001124803.1	asparaginase	-
SOR_RS01160 (SOR_0234)	-	220682..222067 (+)	1386	WP_000453125.1	Cof-type HAD-IIB family hydrolase	-
SOR_RS01165 (SOR_0235)	-	222104..222556 (-)	453	WP_000079162.1	universal stress protein	-
SOR_RS01170 (SOR_0236)	-	222723..223022 (+)	300	WP_000651413.1	hypothetical protein	-
SOR_RS01175 (SOR_0237)	-	223167..224381 (+)	1215	WP_000666454.1	pyridoxal phosphate-dependent aminotransferase	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37214.23 Da
• Isoelectric Point: 5.5033

>NTDB_id=40177 SOR_RS01150 WP_001090635.1 218590..219600(+) (ccpA) [Streptococcus oralis Uo5]
MNTDDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
TLAKGIDDIAEMYKYNIVLANSDEDDEKEVSVVNTLFSKQVDGIIFMGYHLTEKIRSEFSRSRTPVVLAGTVDVEHQLPS
VNIDYKQATIDAVSYLLKENEKIAFVSGPLVDDINGKVRLIGYKEALKKAGHSYSEGLVFESKYSYDDGYALAERLISSQ
ATAAVVTGDELAAGVLNGLADHGVSVPEEFEIITTDDSQIARFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERRSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=40177 SOR_RS01150 WP_001090635.1 218590..219600(+) (ccpA) [Streptococcus oralis Uo5]
ATGAACACAGATGATACAGTAACGATTTATGACGTCGCCCGTGAAGCAGGAGTTTCAATGGCAACAGTTAGCCGTGTCGT
TAATGGCAACAAGAATGTTAAAGAGAACACTCGAAAAAAAGTCCTAGAAGTGATTGATCGCTTGGACTATCGTCCAAATG
CGGTAGCGCGTGGTTTGGCTAGCAAGAAAACAACGACAGTCGGAGTTGTGATTCCGAATATTACCAATGGTTATTTCTCA
ACGCTTGCTAAGGGGATTGACGACATTGCTGAAATGTACAAGTATAACATTGTCCTAGCGAATAGTGATGAGGATGATGA
AAAGGAAGTTTCAGTGGTCAACACTCTCTTTTCAAAACAAGTTGATGGGATTATCTTTATGGGCTATCACTTGACTGAAA
AGATTCGTTCAGAGTTTTCTCGTTCACGGACACCGGTTGTTCTTGCTGGTACTGTGGATGTAGAACACCAACTTCCAAGT
GTAAATATCGACTACAAACAAGCAACGATTGATGCCGTGAGCTACCTTCTCAAAGAAAACGAAAAGATTGCTTTTGTTAG
TGGACCACTTGTTGATGATATCAATGGCAAGGTTCGTTTGATTGGTTACAAGGAAGCCTTGAAAAAAGCTGGACATTCTT
ATAGCGAGGGATTGGTCTTTGAATCAAAATACAGCTATGATGATGGTTATGCCTTGGCAGAACGCTTGATTTCATCACAA
GCTACAGCCGCAGTTGTAACAGGTGATGAATTGGCAGCAGGTGTCCTAAATGGTTTAGCTGACCATGGTGTATCTGTGCC
AGAAGAGTTTGAAATCATTACGACAGATGACTCTCAAATTGCACGATTCACTCGTCCAAACTTGACGACTATTGCCCAAC
CTCTTTATGACTTAGGTGCTATCAGCATGCGTATGTTGACTAAGATTATGCATAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCCTACCTCATGGTTTGACAGAACGCCGCTCTACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (182-332)

3D structure

• AlphaFold DB: I0Q241

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	94.345	100	0.943
ccpA	Streptococcus gordonii str. Challis substr. CH1	88.623	99.405	0.881
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	57.704	98.512	0.568