Detailed information NTG0401659

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: GKO36_RS18635
• Genome accession: NZ_CP046145
• Coordinates: 3734710..3735873 (-)
• Length: 387 a.a.
• NCBI ID: WP_007407484.1
• Uniprot ID: A3KLC1
• Organism: Bacillus velezensis strain PEBA20
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3729710..3740873

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GKO36_RS18605 (GKO36_18480)	-	3729975..3730394 (-)	420	WP_014419009.1	TIGR03826 family flagellar region protein	-
GKO36_RS18610 (GKO36_18485)	comFC	3730468..3731157 (-)	690	WP_197535984.1	ComF family protein	Machinery gene
GKO36_RS18615 (GKO36_18490)	-	3731163..3731447 (-)	285	WP_014419011.1	competence protein ComFB	-
GKO36_RS18620 (GKO36_18495)	comFA	3731505..3732890 (-)	1386	WP_014419012.1	DEAD/DEAH box helicase	Machinery gene
GKO36_RS18625 (GKO36_18500)	-	3732998..3733846 (-)	849	WP_003151387.1	DegV family protein	-
GKO36_RS18630 (GKO36_18505)	degU	3733944..3734633 (-)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
GKO36_RS18635 (GKO36_18510)	degS	3734710..3735873 (-)	1164	WP_007407484.1	two-component sensor histidine kinase DegS	Regulator
GKO36_RS18640 (GKO36_18515)	-	3736096..3736743 (+)	648	WP_007614107.1	YigZ family protein	-
GKO36_RS18645 (GKO36_18520)	-	3736748..3737962 (+)	1215	WP_014419013.1	LCP family protein	-
GKO36_RS18650 (GKO36_18525)	-	3738052..3739128 (-)	1077	WP_003151382.1	MraY family glycosyltransferase	-
GKO36_RS18655 (GKO36_18530)	-	3739261..3740457 (-)	1197	WP_014419014.1	glycosyltransferase	-

Sequence

Protein

• Length: 387 a.a.
• Molecular weight: 45014.78 Da
• Isoelectric Point: 6.8616

>NTDB_id=401659 GKO36_RS18635 WP_007407484.1 3734710..3735873(-) (degS) [Bacillus velezensis strain PEBA20]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide

• Length: 1164 bp

>NTDB_id=401659 GKO36_RS18635 WP_007407484.1 3734710..3735873(-) (degS) [Bacillus velezensis strain PEBA20]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGTAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTTGAAGAACTCAAACAGATCAAACAGCAGG
TCTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCACGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAGTTCAGCGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAACAGCGTGAAAAGCAGCTGCGGGAGCGCAGAGATGATTTAGAACGCCGGCTTTTAGGTCTTCAGGAAATCATTGAAC
GGTCAGAATCGTTGGTCAGCCAAATAACCGTCGTTCTGAATTACCTGAATCAAGACCTTCGCCAAGTAGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGTTTAAGAATCATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGACGGTCCCGCGCAAATGCTGGCAAATGTCATGATGAGATCTGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTACGGCAGAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGACGATCTCGGGCTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGCATCGGAGACACGGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGTCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTA
ACCGCTGATTTTGTCGTTCTCATCATTAAGGACAATGGAAAAGGCTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
GTCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A3KLC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	95.584	99.483	0.951