Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   GJS34_RS07160 Genome accession   NZ_CP046042
Coordinates   1507191..1508543 (-) Length   450 a.a.
NCBI ID   WP_014623188.1    Uniprot ID   A0A6M1KZW6
Organism   Streptococcus equi subsp. zooepidemicus strain TN-714097     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1502191..1513543
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GJS34_RS07145 (GJS34_07170) rnc 1503012..1503704 (-) 693 WP_038674782.1 ribonuclease III -
  GJS34_RS07150 (GJS34_07175) - 1503963..1505477 (-) 1515 WP_014623184.1 helix-turn-helix domain-containing protein -
  GJS34_RS07155 (GJS34_07180) vicX 1506378..1507187 (-) 810 WP_014623187.1 MBL fold metallo-hydrolase Regulator
  GJS34_RS07160 (GJS34_07185) vicK 1507191..1508543 (-) 1353 WP_014623188.1 cell wall metabolism sensor histidine kinase VicK Regulator
  GJS34_RS07165 (GJS34_07190) vicR 1508536..1509246 (-) 711 WP_012515994.1 response regulator YycF Regulator
  GJS34_RS07170 (GJS34_07195) - 1509455..1510471 (-) 1017 WP_014623189.1 DUF3114 domain-containing protein -
  GJS34_RS07175 (GJS34_07200) - 1510517..1511779 (-) 1263 WP_014623190.1 AMP-binding protein -
  GJS34_RS07180 (GJS34_07205) - 1511769..1512884 (-) 1116 WP_014623191.1 acetyl-CoA C-acyltransferase -
  GJS34_RS07185 (GJS34_07210) - 1512881..1513420 (-) 540 WP_014623192.1 hypothetical protein -

Sequence

Protein


Download         Length: 450 a.a.        Molecular weight: 51527.91 Da        Isoelectric Point: 5.5557

>NTDB_id=400593 GJS34_RS07160 WP_014623188.1 1507191..1508543(-) (vicK) [Streptococcus equi subsp. zooepidemicus strain TN-714097]
MTKDIIGNLSAFELAILLLLVFVAFYFIHLAIRDYRNARIIRLMSHKIRDLINGRYTDTINEKADIELMELSEQLNDLSD
VFRLTHENLAQEKNRLASILAYMTDGVLATNRSGKIIMINETAQKQLNLNREQALEKNITDLLDSDSPYTYRELVSKTPI
VTLNRRNDTGEFVSLRLRFALNRRESGFISGLVVVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALK
EDIAPSFIKVSLDETNRMMRMISDLLNLSRIDNHVTQLSVEMTNFTAFMTSILNRFDLVKNQHTSTGKSYEIVRDYPITS
IWLEIDNDKMTQVIENILNNAIKYSPDGGKIVVNMKTTDTQLIISISDEGLGIPKKDLPLIFDRFYRVDKARSRAQGGTG
LGLAIAKEIIKQHRGFIWAKSDYGKGSTFTIVLPYEKDAAIYDEWEDDID

Nucleotide


Download         Length: 1353 bp        

>NTDB_id=400593 GJS34_RS07160 WP_014623188.1 1507191..1508543(-) (vicK) [Streptococcus equi subsp. zooepidemicus strain TN-714097]
ATGACTAAGGACATCATTGGAAACCTTTCTGCATTTGAGCTAGCCATACTCTTATTGCTTGTTTTTGTTGCTTTTTATTT
CATTCATTTAGCCATTCGTGATTATCGCAATGCTCGGATCATTCGTCTGATGAGCCATAAGATAAGAGATTTGATCAATG
GTCGCTATACTGATACGATCAATGAAAAGGCTGATATTGAATTGATGGAGCTGTCTGAGCAGCTCAACGACCTATCAGAT
GTTTTTCGTCTGACCCATGAAAACCTTGCCCAAGAGAAAAATCGTCTTGCTAGTATTTTGGCTTATATGACAGATGGGGT
CCTTGCGACCAATCGTTCCGGCAAGATTATCATGATTAATGAGACTGCTCAAAAGCAGCTCAATTTAAATCGTGAGCAGG
CGCTGGAAAAAAACATTACAGATTTATTAGACAGTGACTCACCTTACACCTACCGAGAGCTGGTCTCAAAAACACCGATT
GTGACCTTAAATCGTCGTAATGACACAGGAGAGTTTGTTTCGCTGCGGCTGCGTTTTGCGCTTAATAGGCGAGAGAGCGG
CTTTATTTCAGGTCTAGTTGTTGTGCTTCATGACACGACTGAGCAGGAAAAGGAGGAGCGTGAGCGCAGACTCTTTGTCT
CAAATGTTAGCCATGAGCTTCGCACACCTTTGACCTCTGTCAAGTCATACCTAGAGGCTCTAGATGAGGGCGCGCTAAAG
GAGGACATAGCCCCAAGCTTTATAAAGGTCTCACTAGACGAAACCAATCGCATGATGCGCATGATTTCAGATTTGCTCAA
TCTATCAAGAATTGATAATCATGTGACACAGCTGTCTGTTGAAATGACCAACTTTACAGCCTTTATGACCTCTATCTTAA
ACCGCTTTGATTTGGTGAAAAATCAGCACACAAGCACAGGAAAATCCTATGAAATTGTCAGAGATTACCCTATTACCTCT
ATTTGGCTAGAAATTGACAATGACAAAATGACGCAGGTTATCGAAAATATTTTAAACAATGCAATCAAATATTCACCCGA
TGGCGGAAAAATTGTCGTCAACATGAAAACAACAGATACCCAGCTAATCATTTCGATTTCTGATGAGGGCTTGGGCATTC
CAAAAAAGGACCTGCCTTTGATTTTTGACCGTTTTTACCGAGTGGATAAGGCTAGGAGTAGAGCTCAAGGAGGGACCGGC
TTAGGGCTGGCTATTGCTAAAGAAATTATCAAGCAGCATCGAGGCTTTATTTGGGCCAAGAGCGATTATGGCAAGGGCTC
AACCTTTACCATTGTGTTACCTTACGAAAAGGATGCTGCTATCTATGATGAATGGGAGGATGATATTGATTAA

Domains

Predicted by InterproScan.

PAS fold (PAS)

(95-197)

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(326-436)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A6M1KZW6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

73.671

92

0.678
  micB Streptococcus pneumoniae Cp1015

66.824

94.444

0.631

Multiple sequence alignment