Detailed information NTG0400587

Bioinformatically predicted

Overview

• Name: comE/blpR
• Type: Regulator
• Locus tag: GJS34_RS05145
• Genome accession: NZ_CP046042
• Coordinates: 1075569..1076306 (+)
• Length: 245 a.a.
• NCBI ID: WP_014622844.1
• Uniprot ID: -
• Organism: Streptococcus equi subsp. zooepidemicus strain TN-714097
• Function: activate transcription of early competence genes; regulation of comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 1070569..1081306

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GJS34_RS05115 (GJS34_05125)	-	1071014..1071919 (-)	906	WP_012677986.1	diacylglycerol/lipid kinase family protein	-
GJS34_RS05120 (GJS34_05130)	trhA	1072029..1072679 (-)	651	WP_012515586.1	PAQR family membrane homeostasis protein TrhA	-
GJS34_RS05125 (GJS34_05135)	-	1072663..1073118 (-)	456	WP_014622841.1	DUF1836 domain-containing protein	-
GJS34_RS05130 (GJS34_05140)	-	1073378..1074133 (+)	756	WP_014622842.1	class I SAM-dependent methyltransferase	-
GJS34_RS05135 (GJS34_05145)	-	1074161..1074499 (+)	339	WP_014622843.1	cupin domain-containing protein	-
GJS34_RS05140 (GJS34_05150)	-	1074501..1074806 (+)	306	WP_012677981.1	AraC family ligand binding domain-containing protein	-
GJS34_RS05145 (GJS34_05155)	comE/blpR	1075569..1076306 (+)	738	WP_014622844.1	response regulator transcription factor	Regulator
GJS34_RS05150 (GJS34_05160)	-	1076679..1076879 (+)	201	WP_012679509.1	ComC/BlpC family leader-containing pheromone/bacteriocin	-
GJS34_RS05155 (GJS34_05165)	-	1076946..1077800 (+)	855	WP_012515593.1	ABC transporter ATP-binding protein	-
GJS34_RS05160 (GJS34_05170)	-	1077806..1078969 (+)	1164	WP_014622845.1	ABC transporter permease subunit	-
GJS34_RS05165 (GJS34_05175)	-	1079231..1079461 (+)	231	WP_012515596.1	Blp family class II bacteriocin	-
GJS34_RS05175 (GJS34_05185)	-	1080331..1080612 (+)	282	WP_080004977.1	lactococcin 972 family bacteriocin	-

Sequence

Protein

• Length: 245 a.a.
• Molecular weight: 28903.28 Da
• Isoelectric Point: 8.2679

>NTDB_id=400587 GJS34_RS05145 WP_014622844.1 1075569..1076306(+) (comE/blpR) [Streptococcus equi subsp. zooepidemicus strain TN-714097]
MNIFILEDDLGQQFRLQMKIQEILDKHHWTCDRFEVYGKPYQLLANVTERGRHQLFFLDSQIRNDEKKGLAVAREIRKRD
PYALIVFVTTHSELMPVSFRYQVSALDFIDKELSMKHFSDRIERAIIYAYEEQENVTSEGLFIFVTAKAQVQVPFSSLLF
IETSSTPHRLILHSQNERIEFYGFLSEVLKQDSRLVQCHRSYVINPYNVSFLDRDKRLLYFKNGQSCMVSRLKLKALEAS
IKALH

Nucleotide

• Length: 738 bp

>NTDB_id=400587 GJS34_RS05145 WP_014622844.1 1075569..1076306(+) (comE/blpR) [Streptococcus equi subsp. zooepidemicus strain TN-714097]
ATGAATATTTTTATTCTCGAAGATGATCTAGGCCAACAGTTTAGGCTTCAGATGAAGATTCAAGAGATATTGGATAAGCA
TCACTGGACTTGTGATCGTTTTGAAGTTTATGGAAAGCCCTACCAGCTTCTGGCAAATGTTACAGAGAGAGGCAGGCATC
AGCTTTTCTTTCTCGATAGTCAAATTCGAAATGATGAGAAAAAGGGCTTAGCTGTTGCTCGTGAGATCAGAAAGCGTGAC
CCTTATGCCCTCATTGTTTTTGTCACGACACATTCTGAGCTTATGCCAGTTTCTTTTCGTTATCAGGTGTCTGCTCTAGA
TTTTATTGATAAGGAATTGTCAATGAAACATTTCTCAGATAGGATTGAAAGAGCCATTATATATGCTTATGAAGAGCAAG
AAAATGTAACCTCAGAGGGCTTATTTATTTTTGTAACGGCTAAGGCTCAGGTGCAGGTTCCTTTTTCAAGCCTATTGTTC
ATTGAGACCTCTAGTACTCCTCACAGGTTGATTTTGCATTCTCAAAACGAGCGAATAGAATTTTATGGCTTTCTTTCAGA
GGTTCTTAAGCAAGATTCCAGACTAGTCCAATGTCATCGTTCTTATGTTATCAATCCTTACAATGTTTCGTTTCTTGATC
GTGATAAGCGTTTACTCTATTTCAAGAACGGGCAGTCTTGCATGGTTTCAAGACTAAAACTGAAAGCACTTGAGGCGTCT
ATTAAGGCTTTGCATTGA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (16-122)

• LytTr DNA-binding domain (LytTR) (151-240)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE/blpR	Streptococcus mutans UA159	53.306	98.776	0.527
comE/comE1	Streptococcus equinus JB1	45.455	98.776	0.449
comE/comE2	Streptococcus equinus JB1	36.885	99.592	0.367