Detailed information NTG0400524

Bioinformatically predicted

Overview

• Name: comE/blpR
• Type: Regulator
• Locus tag: GJS33_RS04850
• Genome accession: NZ_CP046041
• Coordinates: 1028683..1029420 (+)
• Length: 245 a.a.
• NCBI ID: WP_043040551.1
• Uniprot ID: -
• Organism: Streptococcus equi subsp. zooepidemicus strain AZ-45470
• Function: activate transcription of early competence genes; regulation of comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 1023683..1034420

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GJS33_RS04820 (GJS33_04820)	-	1024140..1025045 (-)	906	WP_043025804.1	diacylglycerol/lipid kinase family protein	-
GJS33_RS04825 (GJS33_04825)	trhA	1025155..1025805 (-)	651	WP_012515586.1	PAQR family membrane homeostasis protein TrhA	-
GJS33_RS04830 (GJS33_04830)	-	1025789..1026244 (-)	456	WP_012515587.1	DUF1836 domain-containing protein	-
GJS33_RS04835 (GJS33_04835)	-	1026505..1027260 (+)	756	WP_043030786.1	class I SAM-dependent methyltransferase	-
GJS33_RS04840 (GJS33_04840)	-	1027288..1027626 (+)	339	WP_014622843.1	cupin domain-containing protein	-
GJS33_RS04845 (GJS33_04845)	-	1027628..1027933 (+)	306	WP_111692436.1	AraC family ligand binding domain-containing protein	-
GJS33_RS04850 (GJS33_04850)	comE/blpR	1028683..1029420 (+)	738	WP_043040551.1	response regulator transcription factor	Regulator
GJS33_RS04855 (GJS33_04855)	-	1029793..1029993 (+)	201	WP_042670621.1	ComC/BlpC family leader-containing pheromone/bacteriocin	-
GJS33_RS04860 (GJS33_04860)	-	1030060..1030914 (+)	855	WP_012515593.1	ABC transporter ATP-binding protein	-
GJS33_RS04865 (GJS33_04865)	-	1030920..1032083 (+)	1164	WP_014622845.1	ABC transporter permease subunit	-
GJS33_RS04870 (GJS33_04870)	-	1032345..1032575 (+)	231	WP_111692439.1	Blp family class II bacteriocin	-
GJS33_RS04875 (GJS33_04875)	-	1033368..1034048 (+)	681	WP_228269169.1	thioredoxin family protein	-
GJS33_RS09920	-	1034089..1034220 (+)	132	WP_228269170.1	LPXTG cell wall anchor domain-containing protein	-

Sequence

Protein

• Length: 245 a.a.
• Molecular weight: 28930.36 Da
• Isoelectric Point: 7.8609

>NTDB_id=400524 GJS33_RS04850 WP_043040551.1 1028683..1029420(+) (comE/blpR) [Streptococcus equi subsp. zooepidemicus strain AZ-45470]
MNIFILEDDLGQQFRLEMKIQEILDKHHWTCDRFEVYGKPHQLLANVTERGRHQLFFLDSQIRNDEKKGLAVAREIRKRD
PYALIVFVTTHSELMPVSFRYQVSALDFIDKELSMKHFSDRIERAIIYAYEEQENVTSEGLFIFVTAKAQVQVPFSSLLF
IETSSTPHKLILYSQNERIEFYGFLSEVLKQDPRLVQCHRSYVINPYNVSFLDRDKRLLYFKNGQSCMVSRLKMKALEAS
IKALY

Nucleotide

• Length: 738 bp

>NTDB_id=400524 GJS33_RS04850 WP_043040551.1 1028683..1029420(+) (comE/blpR) [Streptococcus equi subsp. zooepidemicus strain AZ-45470]
ATGAATATTTTTATTCTCGAAGATGATCTAGGCCAACAGTTTAGGCTTGAGATGAAGATTCAAGAGATATTGGATAAGCA
TCACTGGACGTGTGATCGTTTTGAAGTTTATGGAAAGCCCCATCAGCTTCTGGCAAATGTTACAGAGAGAGGCAGGCATC
AGCTTTTCTTTCTCGATAGTCAAATTCGAAATGATGAGAAAAAGGGCTTAGCTGTTGCTCGTGAGATTAGAAAGCGTGAC
CCTTACGCTCTCATTGTTTTTGTCACGACACATTCTGAGCTTATGCCAGTTTCTTTTCGTTATCAGGTGTCTGCTCTAGA
TTTTATCGATAAGGAATTGTCAATGAAACATTTCTCAGATAGGATTGAAAGAGCCATTATATATGCTTATGAAGAGCAAG
AAAATGTAACCTCAGAGGGCTTATTTATTTTTGTAACGGCTAAGGCTCAGGTGCAGGTTCCTTTTTCAAGCCTATTGTTC
ATTGAGACCTCTAGTACTCCTCACAAGTTGATTTTGTATTCTCAAAACGAGCGAATAGAATTTTATGGCTTTCTTTCAGA
GGTTCTTAAGCAAGATCCCAGACTAGTCCAATGTCATCGTTCTTATGTTATCAATCCTTACAATGTTTCGTTTCTTGATC
GTGATAAGCGTTTACTCTATTTCAAGAATGGGCAGTCTTGCATGGTTTCAAGACTAAAAATGAAAGCACTTGAGGCGTCT
ATTAAGGCTTTGTATTGA

Domains

Predicted by InterproScan.

• LytTr DNA-binding domain (LytTR) (151-240)

• Response regulator receiver domain (Response_reg) (18-122)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE/blpR	Streptococcus mutans UA159	54.132	98.776	0.535
comE/comE1	Streptococcus equinus JB1	45.041	98.776	0.445
comE/comE2	Streptococcus equinus JB1	36.885	99.592	0.367