Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   SGGBAA2069_RS03165 Genome accession   NC_015215
Coordinates   596443..597177 (+) Length   244 a.a.
NCBI ID   WP_013642827.1    Uniprot ID   -
Organism   Streptococcus gallolyticus subsp. gallolyticus ATCC BAA-2069     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 591443..602177
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SGGBAA2069_RS03140 (SGGBAA2069_c05590) - 591741..592217 (+) 477 WP_012961630.1 FeoA family protein -
  SGGBAA2069_RS03145 (SGGBAA2069_c05600) feoB 592214..594352 (+) 2139 WP_013642824.1 ferrous iron transport protein B -
  SGGBAA2069_RS11925 (SGGBAA2069_c05610) - 594357..594497 (+) 141 WP_013642825.1 FeoB-associated Cys-rich membrane protein -
  SGGBAA2069_RS03155 (SGGBAA2069_c05620) - 594644..595498 (+) 855 WP_012961632.1 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase -
  SGGBAA2069_RS03160 (SGGBAA2069_c05630) - 595495..596331 (+) 837 WP_013642826.1 NAD(P)H-hydrate dehydratase -
  SGGBAA2069_RS03165 (SGGBAA2069_c05640) comE/blpR 596443..597177 (+) 735 WP_013642827.1 response regulator transcription factor Regulator
  SGGBAA2069_RS03170 (SGGBAA2069_c05650) - 597185..598492 (+) 1308 WP_013642828.1 sensor histidine kinase -
  SGGBAA2069_RS12110 - 598852..598995 (-) 144 WP_158307797.1 hypothetical protein -
  SGGBAA2069_RS03175 (SGGBAA2069_c05660) - 599183..601264 (+) 2082 WP_013642829.1 GBS Bsp-like repeat-containing protein -
  SGGBAA2069_RS03180 (SGGBAA2069_c05670) - 601436..602053 (+) 618 WP_013642830.1 DUF6287 domain-containing protein -

Sequence

Protein


Download         Length: 244 a.a.        Molecular weight: 28150.60 Da        Isoelectric Point: 7.8535

>NTDB_id=40043 SGGBAA2069_RS03165 WP_013642827.1 596443..597177(+) (comE/blpR) [Streptococcus gallolyticus subsp. gallolyticus ATCC BAA-2069]
MLTIFVLEDDFLQQSRIESAINIVLKRNSLKCRSINIFGKPQQLLDAIVERGAHQLFFLDIQIGNDTKKGFEIASQIRQR
DPNATIVFITTHSEFLPVTFQYKVAALDFIDKSLSEEKYLEHVESAIVVTVENMGKSVQEDSFSFETSLAAIQVPFHKIL
YFETSSTVHKVILHTKDERIEFYARLSQIVKADERLFKCHKSFVVNPENITKIDKEKGIVYFETNDTCLVAKLKQKKLIE
KMKK

Nucleotide


Download         Length: 735 bp        

>NTDB_id=40043 SGGBAA2069_RS03165 WP_013642827.1 596443..597177(+) (comE/blpR) [Streptococcus gallolyticus subsp. gallolyticus ATCC BAA-2069]
ATGTTAACTATTTTTGTTTTGGAAGATGATTTTTTACAGCAATCTCGTATTGAAAGTGCCATTAATATTGTTTTAAAACG
CAATTCTTTGAAATGCCGTTCTATTAATATTTTTGGTAAACCTCAACAGTTATTAGATGCTATAGTAGAGCGTGGTGCTC
ATCAACTTTTCTTTTTAGATATTCAGATTGGAAACGATACTAAAAAGGGGTTTGAAATTGCTAGTCAAATTCGTCAGAGA
GATCCAAATGCAACAATTGTTTTTATAACAACCCATTCGGAATTTTTGCCTGTAACATTTCAATATAAAGTTGCAGCACT
TGATTTTATTGATAAATCTTTATCAGAAGAAAAATATTTAGAACATGTTGAATCGGCTATAGTGGTGACCGTGGAGAATA
TGGGAAAAAGCGTGCAAGAAGATTCGTTTAGCTTTGAGACATCTTTAGCAGCAATCCAAGTCCCCTTTCATAAAATTTTA
TATTTTGAAACGTCGTCAACCGTTCATAAAGTTATTTTACACACTAAAGATGAACGTATAGAATTTTATGCTCGATTATC
GCAGATTGTGAAAGCAGATGAAAGACTTTTTAAATGTCATAAATCGTTTGTTGTCAATCCTGAAAATATCACAAAAATTG
ATAAAGAAAAAGGAATAGTTTATTTTGAAACTAATGATACATGCCTAGTCGCAAAATTAAAACAAAAAAAATTAATAGAA
AAGATGAAAAAATAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-123)

LytTr DNA-binding domain (LytTR)

(152-242)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

56.904

97.951

0.557
  comE/comE1 Streptococcus equinus JB1

43.621

99.59

0.434
  comE/comE2 Streptococcus equinus JB1

39.095

99.59

0.389

Multiple sequence alignment