Detailed information    

insolico Bioinformatically predicted

Overview

Name   pknB   Type   Regulator
Locus tag   SGGBAA2069_RS02460 Genome accession   NC_015215
Coordinates   462228..464105 (+) Length   625 a.a.
NCBI ID   WP_012961536.1    Uniprot ID   -
Organism   Streptococcus gallolyticus subsp. gallolyticus ATCC BAA-2069     
Function   modulate the activity of ComDE; modulate the activity of VicKR (predicted from homology)   
Competence regulation

Genomic Context

Location: 457228..469105
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SGGBAA2069_RS02445 (SGGBAA2069_c04270) fmt 459206..460141 (+) 936 WP_013642736.1 methionyl-tRNA formyltransferase -
  SGGBAA2069_RS02450 (SGGBAA2069_c04280) rsmB 460131..461453 (+) 1323 WP_013642737.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  SGGBAA2069_RS02455 (SGGBAA2069_c04290) - 461491..462228 (+) 738 WP_009853567.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  SGGBAA2069_RS02460 (SGGBAA2069_c04300) pknB 462228..464105 (+) 1878 WP_012961536.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  SGGBAA2069_RS02465 (SGGBAA2069_c04310) liaF 464216..464911 (+) 696 WP_013642738.1 cell wall-active antibiotics response protein LiaF -
  SGGBAA2069_RS02470 (SGGBAA2069_c04320) - 464908..465933 (+) 1026 WP_009853570.1 sensor histidine kinase -
  SGGBAA2069_RS02475 (SGGBAA2069_c04330) - 465917..466561 (+) 645 WP_009853571.1 response regulator transcription factor -
  SGGBAA2069_RS02480 (SGGBAA2069_c04340) - 466680..468080 (+) 1401 WP_009853572.1 Cof-type HAD-IIB family hydrolase -
  SGGBAA2069_RS02485 (SGGBAA2069_c04350) - 468080..468436 (+) 357 WP_003063541.1 S1 RNA-binding domain-containing protein -

Sequence

Protein


Download         Length: 625 a.a.        Molecular weight: 67656.85 Da        Isoelectric Point: 5.0759

>NTDB_id=40037 SGGBAA2069_RS02460 WP_012961536.1 462228..464105(+) (pknB) [Streptococcus gallolyticus subsp. gallolyticus ATCC BAA-2069]
MIQIGKLFAGRYRILKSIGRGGMADVYLAKDLILDNEEVAIKVLRTNYQTDQIAVARFQREARAMAELNHPNIVSIRDIG
EEDGQQFLVMEYVDGSDLKKYIQDHAPLSNNEVVRIMEEVLSAMTLAHQQGIVHRDLKPQNILLTKDGTVKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIMLFEMLTGHIPYDGDSAVTIALQHFQKPLPSIIDENKNVP
QALENVVIKATAKRLSDRYASTFEMSRDLMTALSYNRSREPKLVFEDTENTKTLPKVTTSTSVPSTTEQLLKKQKAAKED
KAATENKATKAKTKKKKSRRMFGTLMKIFFAVVIVAIAIFTYLTLTSPSTVSVPDVAGSSLSEAKTTIKSSGLKVGTVHK
VSSDTVESGYVIKTSPTAGSSKKEGSSIDIYVSKGSSGFKIKDYTGQDYQTAVKDLVNNYGVSESQIEIEEVSTSDYDEG
VIISQTPSEGETFKVSGDDKITFKVAAESTVTMPNLTGYTYSEAIAALTALGVSSSHITVYQADPNSSTGYVQVSSPSST
ATVTAQTPYYGETLSGNVVLYLAADEEESSQAPSSSSSESSESKESSSSSSSTDDSSSSTETSDE

Nucleotide


Download         Length: 1878 bp        

>NTDB_id=40037 SGGBAA2069_RS02460 WP_012961536.1 462228..464105(+) (pknB) [Streptococcus gallolyticus subsp. gallolyticus ATCC BAA-2069]
ATGATTCAGATTGGCAAATTATTTGCTGGTCGTTATCGGATCCTCAAATCTATCGGACGGGGTGGAATGGCAGATGTTTA
TCTGGCAAAAGATCTCATTCTTGATAATGAAGAAGTTGCCATTAAGGTGCTTCGGACGAATTATCAGACTGATCAAATTG
CCGTAGCGCGTTTCCAACGGGAAGCGCGTGCCATGGCAGAACTGAACCATCCAAATATCGTCTCGATTCGTGATATTGGA
GAAGAAGACGGACAGCAATTCTTAGTAATGGAATATGTTGATGGCTCGGACTTGAAAAAATACATTCAAGATCATGCTCC
GCTTTCTAATAATGAAGTTGTTAGAATCATGGAAGAAGTCTTATCTGCGATGACTTTGGCGCATCAACAAGGAATTGTTC
ACCGTGATTTAAAACCACAAAATATCTTATTAACCAAAGACGGAACTGTTAAAGTTACTGACTTTGGTATCGCCGTAGCC
TTTGCCGAAACAAGTTTAACGCAAACCAATTCAATGCTAGGTAGTGTGCATTATTTATCGCCTGAACAAGCACGTGGTTC
AAAAGCGACTGTTCAAAGTGATATTTACGCTATGGGGATTATGTTGTTTGAAATGTTAACAGGTCACATCCCATATGATG
GCGATTCAGCTGTTACCATTGCGCTTCAACATTTCCAAAAACCACTTCCTTCCATCATTGATGAGAATAAAAATGTGCCA
CAAGCACTAGAAAATGTTGTTATCAAGGCGACTGCAAAACGTTTAAGTGACCGTTATGCGTCAACTTTTGAAATGAGTCG
TGATTTGATGACGGCACTTTCTTACAACCGTAGCCGTGAACCTAAACTTGTTTTTGAAGATACTGAAAATACAAAGACAC
TTCCAAAGGTAACAACATCAACATCTGTTCCTTCAACGACAGAACAACTCTTGAAGAAACAAAAAGCAGCTAAAGAAGAT
AAAGCAGCAACAGAAAACAAAGCGACTAAAGCTAAAACAAAGAAGAAAAAATCACGTCGTATGTTCGGCACATTGATGAA
AATCTTTTTTGCAGTTGTGATTGTAGCTATTGCTATCTTTACTTACTTGACGTTGACCTCACCATCAACCGTGAGTGTTC
CAGATGTTGCTGGCTCTAGTTTATCAGAAGCAAAAACAACGATAAAATCATCAGGTCTTAAAGTTGGAACCGTTCATAAA
GTATCAAGTGATACCGTTGAGAGTGGTTATGTTATTAAGACAAGTCCAACTGCTGGTTCATCGAAAAAAGAAGGGTCATC
AATTGATATTTACGTATCAAAAGGCTCATCAGGATTCAAGATAAAAGACTATACAGGTCAAGATTATCAAACAGCCGTTA
AAGATTTGGTCAATAATTACGGTGTTTCAGAGTCGCAAATTGAGATTGAAGAAGTCTCAACGTCAGACTATGACGAAGGT
GTTATCATTAGTCAAACGCCTAGCGAAGGTGAAACCTTTAAGGTAAGTGGCGATGATAAGATTACCTTTAAAGTAGCCGC
AGAAAGCACAGTAACAATGCCAAATCTGACAGGCTATACTTATTCAGAAGCTATTGCTGCCTTGACGGCTCTAGGTGTGT
CAAGTTCACATATTACGGTTTATCAAGCCGACCCAAATTCTTCTACGGGTTATGTGCAAGTAAGCTCACCATCTTCAACA
GCAACTGTCACTGCTCAGACACCTTATTATGGTGAAACGTTAAGTGGTAACGTGGTACTTTATCTAGCAGCTGATGAAGA
AGAAAGCTCACAGGCACCATCGTCATCAAGCTCAGAATCCTCTGAATCAAAAGAATCAAGTTCATCAAGCAGTAGTACAG
ATGACAGTAGCTCATCGACAGAAACAAGTGATGAATAA

Domains

Predicted by InterproScan.

PASTA domain (PASTA)

(371-434)

PASTA domain (PASTA)

(440-505)

PASTA domain (PASTA)

(511-575)

Protein kinase domain (Pkinase)

(12-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pknB Streptococcus mutans UA159

68.313

93.92

0.642
  stkP/pknB Streptococcus salivarius strain HSISS4

65.025

94.24

0.613
  stkP Streptococcus pneumoniae TIGR4

54.795

93.44

0.512
  stkP Streptococcus pneumoniae D39

54.623

93.44

0.51
  stkP Streptococcus pneumoniae R6

54.623

93.44

0.51
  stkP Streptococcus pneumoniae Rx1

54.452

93.44

0.509

Multiple sequence alignment