Detailed information NTG0040017

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: SGGBAA2069_RS00355
• Genome accession: NC_015215
• Coordinates: 53663..54562 (+)
• Length: 299 a.a.
• NCBI ID: WP_009853198.1
• Uniprot ID: -
• Organism: Streptococcus gallolyticus subsp. gallolyticus ATCC BAA-2069
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 48663..59562

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SGGBAA2069_RS00330 (SGGBAA2069_c00330)	-	48862..49311 (+)	450	WP_012961319.1	DUF523 domain-containing protein	-
SGGBAA2069_RS00335 (SGGBAA2069_c00340)	purE	49311..49799 (+)	489	WP_009853194.1	5-(carboxyamino)imidazole ribonucleotide mutase	-
SGGBAA2069_RS00340 (SGGBAA2069_c00350)	purK	49786..50859 (+)	1074	WP_009853195.1	5-(carboxyamino)imidazole ribonucleotide synthase	-
SGGBAA2069_RS00345 (SGGBAA2069_c00360)	-	50870..51916 (+)	1047	WP_014619874.1	hypothetical protein	-
SGGBAA2069_RS00350 (SGGBAA2069_c00370)	purB	52218..53516 (+)	1299	WP_009853197.1	adenylosuccinate lyase	-
SGGBAA2069_RS00355 (SGGBAA2069_c00380)	comR	53663..54562 (+)	900	WP_009853198.1	helix-turn-helix domain-containing protein	Regulator
SGGBAA2069_RS00360 (SGGBAA2069_c00390)	-	55804..56235 (+)	432	WP_012961321.1	low molecular weight protein-tyrosine-phosphatase	-
SGGBAA2069_RS00365 (SGGBAA2069_c00400)	-	56255..56635 (+)	381	WP_009853201.1	membrane protein	-
SGGBAA2069_RS00370 (SGGBAA2069_c00410)	-	56632..58425 (+)	1794	WP_012961323.1	acyltransferase family protein	-

Sequence

Protein

• Length: 299 a.a.
• Molecular weight: 34967.15 Da
• Isoelectric Point: 5.1732

>NTDB_id=40017 SGGBAA2069_RS00355 WP_009853198.1 53663..54562(+) (comR) [Streptococcus gallolyticus subsp. gallolyticus ATCC BAA-2069]
MEKFGIKVRALREKKGISREEFCGDETELSVRQLARIEKGQSVPTLNKVGYIAKVLGVTIGELTDGKNLELPTRYKELKY
LLLRTPTYGDKERLKRQTSYFDEISEKYYEVIPEEERLIIDCLQSKIDVHFSDDVNFGEGILNDYFDQVRRKKNFQINDL
ILIDLYFACLASAKSFVGIYSLDLYDELMECLLNQENLSPETSLILNNVLLNNVDLVLRFHRESFMKRIIIKSDTIMTSV
HDFQRRPVLSLVEWKYYLQFKKDFLAAQKSYSNAILFANLIGDTYLENKLIEEWNNDTT

Nucleotide

• Length: 900 bp

>NTDB_id=40017 SGGBAA2069_RS00355 WP_009853198.1 53663..54562(+) (comR) [Streptococcus gallolyticus subsp. gallolyticus ATCC BAA-2069]
TTGGAAAAGTTTGGGATTAAAGTACGTGCATTAAGAGAGAAAAAAGGGATTTCACGTGAAGAATTCTGTGGTGATGAAAC
AGAATTATCTGTGAGACAGCTAGCTAGAATTGAAAAAGGACAATCCGTCCCAACTCTTAATAAGGTGGGATATATTGCAA
AAGTATTAGGAGTAACTATTGGTGAGTTAACTGATGGTAAAAATTTAGAACTTCCCACTCGGTATAAGGAGTTAAAATAT
TTACTATTACGAACACCAACTTATGGGGATAAGGAACGTCTTAAGAGACAAACTTCATATTTTGATGAAATTTCAGAAAA
ATACTATGAAGTTATACCTGAAGAAGAACGCTTAATTATTGATTGTTTACAATCGAAGATTGATGTTCATTTTAGTGATG
ATGTTAATTTTGGTGAAGGAATTTTAAATGATTATTTTGACCAAGTTAGACGAAAGAAGAACTTTCAAATTAATGATTTG
ATTTTAATAGATTTATATTTTGCTTGCCTTGCTTCTGCTAAATCGTTTGTGGGAATCTATAGCTTAGATTTGTATGATGA
ATTAATGGAGTGTTTACTAAATCAAGAAAATCTTTCACCAGAAACTTCTTTGATTTTAAATAATGTTTTGTTAAATAATG
TAGATTTGGTTTTACGATTCCATAGAGAATCTTTTATGAAACGAATTATTATAAAAAGTGACACTATCATGACAAGTGTT
CATGATTTTCAAAGACGTCCAGTTTTAAGTTTAGTTGAGTGGAAATATTATTTACAATTTAAAAAAGATTTTTTAGCGGC
ACAAAAATCTTACTCCAATGCTATTTTATTTGCTAACTTAATTGGAGATACTTATTTGGAAAATAAGTTAATAGAAGAAT
GGAATAATGACACAACATGA

Domains

Predicted by InterproScan.

• Helix-turn-helix (HTH_3) (8-63)

• ComR tetratricopeptide (ComR_TPR) (72-294)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus infantarius subsp. infantarius ATCC BAA-102	72.474	95.987	0.696
comR	Streptococcus mutans UA159	54.515	100	0.545
comR	Streptococcus pyogenes MGAS8232	49.333	100	0.495
comR	Streptococcus pyogenes MGAS315	47.315	99.666	0.472
comR	Streptococcus suis P1/7	39.799	100	0.398
comR	Streptococcus suis 05ZYH33	39.799	100	0.398
comR	Streptococcus suis D9	37.71	99.331	0.375