Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   HR073_RS12390 Genome accession   NZ_CP054227
Coordinates   2609286..2609942 (-) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain EcPF15     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2604286..2614942
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HR073_RS12360 (HR073_12350) yecA 2605537..2606202 (-) 666 WP_000847882.1 UPF0149 family protein YecA -
  HR073_RS12380 (HR073_12370) pgsA 2606852..2607400 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  HR073_RS12385 (HR073_12375) uvrC 2607457..2609289 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  HR073_RS12390 (HR073_12380) letA 2609286..2609942 (-) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  HR073_RS12395 (HR073_12385) yecU 2610238..2610414 (+) 177 WP_000590347.1 protein YecU -
  HR073_RS12400 (HR073_12390) yecF 2610401..2610625 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  HR073_RS12405 (HR073_12395) sdiA 2610693..2611415 (-) 723 WP_001154273.1 transcriptional regulator SdiA -
  HR073_RS12410 (HR073_12400) tcyN 2611645..2612397 (-) 753 WP_001272982.1 L-cystine ABC transporter ATP-binding protein TcyN -
  HR073_RS12415 (HR073_12405) tcyL 2612394..2613062 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  HR073_RS12420 (HR073_12410) dcyD 2613077..2614063 (-) 987 WP_001128229.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=398326 HR073_RS12390 WP_000611328.1 2609286..2609942(-) (letA) [Escherichia coli strain EcPF15]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=398326 HR073_RS12390 WP_000611328.1 2609286..2609942(-) (letA) [Escherichia coli strain EcPF15]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACGGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTAGTGAGTGCGATCCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482

Multiple sequence alignment