Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   HR074_RS09275 Genome accession   NZ_CP054224
Coordinates   1937446..1938102 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain EcPF16     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1932446..1943102
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HR074_RS09245 (HR074_09245) dcyD 1933327..1934313 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  HR074_RS09250 (HR074_09250) tcyL 1934328..1934996 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  HR074_RS09255 (HR074_09255) tcyN 1934993..1935745 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  HR074_RS09260 (HR074_09260) sdiA 1935975..1936695 (+) 721 Protein_1825 transcriptional regulator SdiA -
  HR074_RS09265 (HR074_09265) yecF 1936763..1936987 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  HR074_RS09270 (HR074_09270) yecU 1936974..1937150 (-) 177 WP_000590344.1 protein YecU -
  HR074_RS24120 - 1937188..1937304 (-) 117 WP_001302039.1 hypothetical protein -
  HR074_RS09275 (HR074_09275) letA 1937446..1938102 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  HR074_RS09280 (HR074_09280) uvrC 1938099..1939931 (+) 1833 WP_176321024.1 excinuclease ABC subunit UvrC Machinery gene
  HR074_RS09285 (HR074_09285) pgsA 1939988..1940536 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  HR074_RS09305 (HR074_09305) - 1941531..1941812 (+) 282 WP_071589622.1 hypothetical protein -
  HR074_RS09310 (HR074_09310) - 1942004..1942144 (-) 141 WP_000078920.1 Hok/Gef family protein -
  HR074_RS09315 (HR074_09315) - 1942335..1942595 (-) 261 WP_000488113.1 ogr/Delta-like zinc finger family protein -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=398247 HR074_RS09275 WP_000611328.1 1937446..1938102(+) (letA) [Escherichia coli strain EcPF16]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=398247 HR074_RS09275 WP_000611328.1 1937446..1938102(+) (letA) [Escherichia coli strain EcPF16]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGTCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482

Multiple sequence alignment