Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   HRL54_RS09425 Genome accession   NZ_CP054191
Coordinates   1969762..1971594 (+) Length   610 a.a.
NCBI ID   WP_001283437.1    Uniprot ID   -
Organism   Escherichia coli strain TH9F11     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1964762..1976594
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HRL54_RS09390 (HRL54_09340) dcyD 1964989..1965975 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  HRL54_RS09395 (HRL54_09345) tcyL 1965990..1966658 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  HRL54_RS09400 (HRL54_09350) tcyN 1966655..1967407 (+) 753 WP_001273009.1 L-cystine ABC transporter ATP-binding protein TcyN -
  HRL54_RS09405 (HRL54_09355) sdiA 1967637..1968359 (+) 723 WP_001154271.1 transcriptional regulator SdiA -
  HRL54_RS09410 (HRL54_09360) yecF 1968426..1968650 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  HRL54_RS09415 (HRL54_09365) yecU 1968637..1968813 (-) 177 WP_000590347.1 protein YecU -
  HRL54_RS26415 - 1968896..1968967 (-) 72 Protein_1839 transcriptional regulator -
  HRL54_RS09420 (HRL54_09370) letA 1969109..1969765 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  HRL54_RS09425 (HRL54_09375) uvrC 1969762..1971594 (+) 1833 WP_001283437.1 excinuclease ABC subunit UvrC Machinery gene
  HRL54_RS09430 (HRL54_09380) pgsA 1971651..1972199 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  HRL54_RS09450 (HRL54_09400) yecA 1972849..1973514 (+) 666 WP_000847902.1 UPF0149 family protein YecA -
  HRL54_RS09455 (HRL54_09405) tyrP 1973576..1974787 (-) 1212 WP_000797573.1 tyrosine transporter TyrP -
  HRL54_RS09460 (HRL54_09410) yecH 1974978..1975217 (+) 240 WP_000377224.1 YecH family metal-binding protein -
  HRL54_RS09465 (HRL54_09415) ftnA 1975255..1975752 (-) 498 WP_000917208.1 non-heme ferritin -
  HRL54_RS09470 (HRL54_09420) yecR 1975923..1976246 (-) 324 WP_001237869.1 YecR-like lipofamily protein -

Sequence

Protein


Download         Length: 610 a.a.        Molecular weight: 68206.06 Da        Isoelectric Point: 9.3685

>NTDB_id=397939 HRL54_RS09425 WP_001283437.1 1969762..1971594(+) (uvrC) [Escherichia coli strain TH9F11]
MSDQFDAKAFLKTVTSQPGVYRMYDAGGTVIYVGKAKDLKKRLSSYFRSNLASRKTEAMVAQIQQIDVTVTHTETEALLL
EHNYIKLYQPRYNVLLRDDKSYPFIFLSGDTHPRLAMHRGAKHAKGEYFGPFPNGYAVRETLALLQKIFPIRQCENSVYR
NRSRPCLQYQIGRCLGPCVEGLVSEEEYAQQVEYVRLFLSGKDDQVLTQLISRMETASQNLEFEEAARIRDQIQAVRRVT
EKQFVSNTGDDLDVIGVAFDAGMACVHVLFIRQGKVLGSRSYFPKVPGGTELSEVVETFVGQFYLQGSQMRTLPGEILLD
FNLSDKTLLADSLSELAGRKINVQTKPRGDRARYLKLARTNAATALTSKLSQQSTVHQRLTALASVLKLPEVKRMECFDI
SHTMGEQTVASCVVFDANGPLRAEYRRYNITGITPGDDYAAMNQVLRRRYGKAIDDSKIPDVILIDGGKGQLAQAKNVFA
ELDVSWDKNHPLLLGVAKGADRKAGLETLFFEPEGEGFSLPPDSPALHVIQHIRDESHDHAIGGHRKKRAKVKNTSSLET
IEGVGPKRRQMLLKYMGGLQGLRNASVEEIAKVPGISQGLAEKIFWSLKH

Nucleotide


Download         Length: 1833 bp        

>NTDB_id=397939 HRL54_RS09425 WP_001283437.1 1969762..1971594(+) (uvrC) [Escherichia coli strain TH9F11]
GTGAGTGATCAGTTTGACGCAAAAGCGTTTTTAAAAACCGTAACCAGCCAGCCAGGCGTTTATCGCATGTACGATGCTGG
TGGTACGGTTATCTATGTCGGCAAAGCGAAAGACCTGAAAAAACGGCTTTCCAGCTATTTCCGTAGCAACCTCGCTTCGC
GCAAAACCGAAGCGATGGTCGCCCAGATCCAGCAAATTGATGTAACGGTTACTCACACAGAAACCGAAGCGCTGTTGCTG
GAACACAACTACATCAAACTCTATCAGCCGCGTTACAACGTTTTGCTACGCGATGATAAATCATATCCTTTTATCTTCCT
GAGTGGTGATACCCACCCGCGTCTGGCGATGCATCGTGGTGCGAAGCATGCCAAAGGTGAATATTTCGGCCCGTTCCCGA
ATGGCTATGCCGTACGTGAAACACTGGCGCTACTGCAAAAGATTTTCCCCATTCGCCAGTGCGAAAATAGTGTTTATCGC
AATCGCTCGCGTCCGTGTCTGCAATACCAGATAGGGCGCTGTCTGGGACCGTGCGTTGAAGGACTGGTGAGTGAAGAAGA
ATACGCTCAGCAGGTCGAGTATGTGCGCCTGTTTTTGTCTGGCAAAGATGATCAGGTGCTTACGCAACTCATTAGTCGTA
TGGAAACTGCCAGCCAGAATCTGGAGTTTGAAGAAGCTGCACGTATTCGCGACCAAATTCAGGCGGTGCGACGCGTCACC
GAAAAACAATTCGTTTCCAATACCGGCGACGACCTCGACGTTATTGGTGTGGCGTTCGATGCGGGCATGGCTTGTGTCCA
CGTATTGTTCATTCGTCAGGGCAAAGTGCTCGGCAGCCGCAGCTATTTCCCGAAAGTGCCTGGCGGTACGGAACTGAGCG
AGGTGGTAGAAACCTTCGTAGGCCAGTTCTATTTACAAGGCAGCCAGATGCGCACCTTACCGGGTGAGATCCTGCTCGAT
TTTAATCTTAGCGATAAAACGCTGCTCGCCGATTCCCTTTCAGAACTGGCGGGACGCAAGATTAATGTTCAAACCAAACC
TCGCGGCGATAGGGCGCGTTATCTGAAACTCGCGCGCACCAATGCGGCGACGGCCTTAACCAGCAAACTTTCGCAGCAAT
CTACCGTTCACCAGCGACTGACCGCGCTTGCCAGCGTGTTGAAATTGCCGGAAGTGAAGCGGATGGAGTGCTTTGACATC
AGCCATACCATGGGCGAACAAACCGTCGCTTCCTGTGTGGTGTTTGATGCTAACGGCCCGCTGCGTGCGGAGTATCGGCG
CTATAACATTACAGGCATCACGCCGGGCGATGATTATGCGGCGATGAATCAGGTGCTGCGTCGGCGTTATGGTAAAGCCA
TTGACGACAGTAAGATCCCGGATGTGATCCTTATCGACGGCGGCAAAGGCCAGCTTGCGCAGGCGAAAAATGTCTTCGCC
GAACTGGATGTCTCATGGGATAAAAATCATCCGCTGCTACTTGGCGTTGCCAAAGGAGCAGATCGTAAGGCTGGACTGGA
AACGCTGTTCTTTGAGCCGGAAGGTGAGGGATTTAGTTTGCCGCCAGATTCACCCGCGCTGCATGTTATCCAGCATATTC
GCGATGAATCACATGATCACGCGATTGGCGGGCACCGTAAAAAACGGGCGAAGGTCAAAAATACCAGTTCCCTGGAAACC
ATTGAAGGCGTCGGGCCAAAACGTCGGCAAATGTTGTTGAAATATATGGGCGGTTTGCAAGGTTTACGTAACGCCAGCGT
CGAGGAAATTGCAAAAGTGCCGGGTATTTCGCAAGGTCTGGCAGAAAAGATCTTCTGGTCGTTGAAACATTGA

Domains

Predicted by InterProScan.

UvrB/uvrC motif (UVR)

(205-237)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-542)

Helix-hairpin-helix domain (HHH_5)

(558-609)

GIY-YIG catalytic domain (GIY-YIG)

(18-93)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

37.727

99.508

0.375
  uvrC Streptococcus pneumoniae R6

37.397

99.508

0.372
  uvrC Streptococcus pneumoniae D39

37.397

99.508

0.372

Multiple sequence alignment