Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   HRL54_RS09420 Genome accession   NZ_CP054191
Coordinates   1969109..1969765 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain TH9F11     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1964109..1974765
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HRL54_RS09390 (HRL54_09340) dcyD 1964989..1965975 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  HRL54_RS09395 (HRL54_09345) tcyL 1965990..1966658 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  HRL54_RS09400 (HRL54_09350) tcyN 1966655..1967407 (+) 753 WP_001273009.1 L-cystine ABC transporter ATP-binding protein TcyN -
  HRL54_RS09405 (HRL54_09355) sdiA 1967637..1968359 (+) 723 WP_001154271.1 transcriptional regulator SdiA -
  HRL54_RS09410 (HRL54_09360) yecF 1968426..1968650 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  HRL54_RS09415 (HRL54_09365) yecU 1968637..1968813 (-) 177 WP_000590347.1 protein YecU -
  HRL54_RS26415 - 1968896..1968967 (-) 72 Protein_1839 transcriptional regulator -
  HRL54_RS09420 (HRL54_09370) letA 1969109..1969765 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  HRL54_RS09425 (HRL54_09375) uvrC 1969762..1971594 (+) 1833 WP_001283437.1 excinuclease ABC subunit UvrC Machinery gene
  HRL54_RS09430 (HRL54_09380) pgsA 1971651..1972199 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  HRL54_RS09450 (HRL54_09400) yecA 1972849..1973514 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=397938 HRL54_RS09420 WP_000611335.1 1969109..1969765(+) (letA) [Escherichia coli strain TH9F11]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=397938 HRL54_RS09420 WP_000611335.1 1969109..1969765(+) (letA) [Escherichia coli strain TH9F11]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486