Detailed information NTG0397475

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: HRE60_RS00295
• Genome accession: NZ_CP054153
• Coordinates: 49265..51823 (+)
• Length: 852 a.a.
• NCBI ID: WP_181670840.1
• Uniprot ID: -
• Organism: Streptococcus salivarius strain DB-B5
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 44265..56823

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HRE60_RS00275 (HRE60_00275)	purB	44464..45762 (+)	1299	WP_002886310.1	adenylosuccinate lyase	-
HRE60_RS00280 (HRE60_00280)	argS	46639..48330 (-)	1692	WP_181670839.1	arginine--tRNA ligase	-
HRE60_RS00285 (HRE60_00285)	argR	48485..48913 (+)	429	WP_171963651.1	arginine repressor	-
HRE60_RS00290 (HRE60_00290)	-	48913..49272 (+)	360	WP_002889586.1	YlbF family regulator	-
HRE60_RS00295 (HRE60_00295)	hexA	49265..51823 (+)	2559	WP_181670840.1	DNA mismatch repair protein MutS	Machinery gene
HRE60_RS00300 (HRE60_00300)	-	51857..52312 (-)	456	WP_004181953.1	DUF3021 domain-containing protein	-
HRE60_RS00305 (HRE60_00305)	-	52309..52746 (-)	438	WP_118189691.1	LytTR family DNA-binding domain-containing protein	-
HRE60_RS00310 (HRE60_00310)	-	52925..53230 (+)	306	WP_048674007.1	hypothetical protein	-
HRE60_RS00315 (HRE60_00315)	hexB	53280..55217 (+)	1938	WP_181670841.1	DNA mismatch repair endonuclease MutL	Machinery gene
HRE60_RS00320 (HRE60_00320)	-	55348..55569 (+)	222	WP_002886321.1	hypothetical protein	-
HRE60_RS00325 (HRE60_00325)	ruvA	55727..56317 (+)	591	WP_004181981.1	Holliday junction branch migration protein RuvA	Machinery gene

Sequence

Protein

• Length: 852 a.a.
• Molecular weight: 95551.74 Da
• Isoelectric Point: 4.6413

>NTDB_id=397475 HRE60_RS00295 WP_181670840.1 49265..51823(+) (hexA) [Streptococcus salivarius strain DB-B5]
MAKEKISPGMQQYLDIKENYPDAFLLFRMGDFYELFYDDAVKAAQILEISLTSRNKNADNPIPMAGVPYHSAQSYIDVLV
EMGYKVAIAEQMEDPKQAVGVVKREVVQVITPGTVVDSSKPDNANNFLVAIDKAGSRFGLAYMDVSTGEFFATELDDFSS
VYSEIQNLKAREVVVGYDLPEADEQVLVKQLNLLLSKETEVYDDVHLIDTSLTDLESSVAGKLLQYVHRTQMRELSHLQK
AQHYEIKDYLQMSYATKSSLDLLENARTGKKHGSLFWLLDETKTAMGMRLLRTWIDRPLVNQAAIVERQNIIQVFLDNFF
ERSDLTESLKGVYDIERLASRVSFGKANPKDLIQLGHTLAQVPVIKAILESFDDEALSRLLQELDALPELESLIRSAIDP
DAPATITEGGIIRAGFDETLDKYRKVMSEGTSWIADIEAKEREASGITTLKIDYNRKDGYYFHVTNSNLSLVPDHFFRKA
TLKNSERFGTAELAKIEGEMLEAREKSSTLEYDIFMRVREQVERYIDRLQSLAKAIATVDVLQSLAVTAETNHYVRPVFN
DEHRIVIDQGRHAVVEKVMGVQEYIPNTITFDSQTNVQLITGPNMSGKSTYMRQLALSVVMAQMGAYVPADSIDLPVFDA
IYTRIGAADDLISGQSTFMVEMMEANQAIKRATPNSLIIFDELGRGTATYDGMALAQSIIEFIHDKVGAKTMFATHYHEL
TALSNTLTHLVNVHVATLEKDGEVTFLHKIVDGPADKSYGIHVAKIAGLPADLLERADTILTQLEGETVTIQPLEKVSPQ
EKPATETHVNEQISLFDDFTENPVLQELRDLDIYNMTPMQVMMAVADLKQKL

Nucleotide

• Length: 2559 bp

>NTDB_id=397475 HRE60_RS00295 WP_181670840.1 49265..51823(+) (hexA) [Streptococcus salivarius strain DB-B5]
ATGGCTAAGGAAAAAATATCTCCAGGAATGCAGCAGTATTTGGATATCAAGGAAAATTATCCAGATGCTTTTTTGCTCTT
CCGTATGGGTGATTTTTACGAATTATTTTATGATGATGCCGTTAAGGCTGCCCAGATTTTGGAAATTAGCCTAACCAGTC
GGAATAAGAACGCCGATAATCCCATTCCTATGGCTGGTGTTCCTTACCATTCAGCTCAATCCTATATTGATGTCTTGGTT
GAGATGGGCTACAAGGTAGCCATTGCTGAGCAGATGGAGGATCCTAAACAGGCTGTTGGTGTGGTTAAGCGTGAGGTGGT
TCAGGTTATCACGCCAGGGACAGTGGTTGACAGTTCTAAACCTGATAATGCCAACAATTTCTTGGTAGCTATTGACAAGG
CTGGAAGTCGATTCGGCCTGGCCTATATGGATGTGTCAACGGGTGAATTTTTTGCGACAGAGTTGGACGATTTCAGTTCA
GTTTATAGTGAAATTCAGAACCTTAAGGCACGTGAAGTAGTGGTTGGTTATGATTTACCCGAAGCTGATGAACAAGTTTT
GGTGAAGCAACTCAACCTTCTACTTTCCAAGGAAACAGAGGTTTACGATGATGTCCACTTGATTGACACTAGCTTGACAG
ACCTGGAAAGCAGTGTAGCGGGTAAACTTCTCCAGTATGTGCACCGTACTCAGATGCGCGAGCTTAGCCATTTACAAAAG
GCTCAGCACTATGAGATTAAGGATTACTTGCAGATGTCCTATGCGACCAAGTCAAGTTTGGATTTGTTGGAAAATGCTAG
AACAGGTAAGAAACACGGTTCTCTTTTCTGGCTCTTGGATGAAACCAAGACAGCTATGGGGATGCGTCTCTTGCGTACTT
GGATTGACCGTCCTTTAGTGAATCAGGCTGCAATCGTGGAGCGTCAGAATATTATCCAAGTTTTCTTGGACAATTTCTTC
GAGCGTAGTGACTTGACTGAGAGTCTTAAAGGGGTTTACGATATTGAGCGCTTGGCTAGTCGTGTTTCCTTCGGAAAGGC
TAATCCTAAAGATTTGATTCAACTAGGTCATACCCTAGCTCAGGTTCCGGTCATTAAGGCAATTTTGGAGTCTTTTGATG
ATGAGGCCTTGTCACGTCTTTTACAAGAGTTAGATGCTCTGCCAGAATTAGAGAGTCTGATTCGGTCGGCTATCGATCCC
GATGCTCCTGCAACCATTACAGAAGGTGGCATTATCCGTGCTGGTTTTGATGAGACCTTGGACAAGTATCGCAAGGTGAT
GAGTGAGGGGACGTCATGGATCGCAGACATCGAAGCCAAGGAACGTGAAGCGTCTGGTATTACAACACTAAAAATTGATT
ATAACCGTAAAGATGGTTATTACTTCCATGTGACCAACTCTAATCTTAGCTTGGTCCCTGACCATTTCTTCCGCAAGGCA
ACCCTGAAAAATTCAGAGCGCTTTGGAACTGCTGAGTTGGCTAAGATTGAAGGTGAGATGCTTGAGGCACGTGAAAAGTC
ATCAACGCTAGAGTATGATATTTTCATGCGTGTCCGTGAGCAGGTTGAACGCTATATTGACCGTTTGCAATCTTTGGCTA
AGGCCATTGCGACAGTCGATGTGCTTCAGAGTTTGGCTGTTACAGCAGAGACTAATCATTATGTTCGTCCTGTGTTCAAT
GATGAGCATCGTATCGTTATTGATCAAGGCCGTCATGCGGTGGTTGAGAAGGTTATGGGTGTTCAGGAGTACATTCCAAA
CACGATTACCTTTGACAGTCAGACCAATGTTCAGCTCATCACAGGACCAAATATGAGTGGTAAATCTACCTATATGCGTC
AGTTGGCCTTGTCAGTCGTTATGGCTCAGATGGGGGCTTACGTGCCAGCAGATAGTATTGATTTGCCAGTTTTTGACGCT
ATCTATACACGTATTGGTGCTGCAGATGATCTGATTTCAGGTCAGTCGACCTTCATGGTTGAGATGATGGAGGCTAATCA
GGCCATTAAGCGGGCGACACCTAATTCCTTGATTATTTTTGATGAGTTAGGACGTGGGACAGCCACCTATGACGGTATGG
CTCTGGCCCAGTCTATCATTGAGTTTATTCATGACAAGGTTGGGGCTAAAACCATGTTTGCTACCCATTATCATGAGTTG
ACAGCCCTGTCAAATACTTTGACACACCTTGTCAACGTTCATGTGGCGACACTTGAAAAGGACGGAGAGGTGACTTTCCT
TCACAAGATTGTCGATGGCCCAGCCGATAAATCTTATGGTATTCATGTAGCTAAGATTGCAGGTTTACCAGCAGATTTAC
TGGAACGTGCTGACACCATCTTGACACAATTGGAGGGCGAGACAGTTACCATCCAACCTCTGGAAAAGGTATCGCCTCAA
GAGAAGCCAGCCACTGAAACACATGTCAACGAGCAAATCTCTCTCTTTGATGATTTTACTGAAAATCCGGTTCTTCAAGA
GTTACGTGATTTGGATATTTACAATATGACACCGATGCAGGTTATGATGGCTGTAGCAGATTTAAAACAGAAACTATAA

Domains

Predicted by InterProScan.

• MutS family domain IV (MutS_IV) (415-505)

• MutS domain III (MutS_III) (256-546)

• MutS domain V (MutS_V) (599-785)

• MutS domain I (MutS_I) (8-118)

• MutS domain II (MutS_II) (126-239)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	73.857	100	0.739
mutS	Pseudomonas stutzeri strain ATCC 17587	36.185	100	0.367