Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   FOC71_RS01355 Genome accession   NZ_CP053999
Coordinates   256186..258132 (-) Length   648 a.a.
NCBI ID   WP_037584706.1    Uniprot ID   -
Organism   Streptococcus intermedius strain FDAARGOS_769     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 251186..263132
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FOC71_RS01325 (FOC71_01325) - 252685..253027 (+) 343 Protein_248 transposase -
  FOC71_RS01330 (FOC71_01330) - 253043..253717 (-) 675 WP_003075288.1 CPBP family intramembrane glutamic endopeptidase -
  FOC71_RS01335 (FOC71_01335) - 253722..254276 (-) 555 WP_003075291.1 DNA-3-methyladenine glycosylase I -
  FOC71_RS01340 (FOC71_01340) ruvA 254286..254876 (-) 591 WP_003075294.1 Holliday junction branch migration protein RuvA Machinery gene
  FOC71_RS01345 (FOC71_01345) - 255044..255547 (+) 504 WP_037584704.1 helix-turn-helix domain-containing protein -
  FOC71_RS01350 (FOC71_01350) - 255531..256040 (+) 510 WP_003075298.1 RDD family protein -
  FOC71_RS01355 (FOC71_01355) hexB 256186..258132 (-) 1947 WP_037584706.1 DNA mismatch repair endonuclease MutL Machinery gene
  FOC71_RS01360 (FOC71_01360) - 258227..259372 (-) 1146 WP_003075301.1 site-specific integrase -
  FOC71_RS01365 (FOC71_01365) - 259529..260359 (-) 831 WP_003075304.1 KilA-N domain-containing protein -
  FOC71_RS01370 (FOC71_01370) - 260590..261306 (-) 717 WP_003075306.1 helix-turn-helix domain-containing protein -
  FOC71_RS01375 (FOC71_01375) - 261446..261664 (+) 219 WP_003075308.1 helix-turn-helix domain-containing protein -
  FOC71_RS01380 (FOC71_01380) - 261679..262293 (+) 615 WP_003075310.1 Rha family transcriptional regulator -
  FOC71_RS01385 (FOC71_01385) - 262298..262465 (+) 168 WP_003075312.1 hypothetical protein -
  FOC71_RS01390 (FOC71_01390) - 262808..263086 (+) 279 WP_003027794.1 hypothetical protein -

Sequence

Protein


Download         Length: 648 a.a.        Molecular weight: 73421.97 Da        Isoelectric Point: 5.1595

>NTDB_id=396982 FOC71_RS01355 WP_037584706.1 256186..258132(-) (hexB) [Streptococcus intermedius strain FDAARGOS_769]
MSKIIELPEKLANQIAAGEVIERPSSVVKELIENSIDAGATQIIVEIEEAGLKSIQVIDNGEGIEHEEVPLALRRHATSK
IKKQADLFRIRTLGFRGEALPSIASVSCLTIETATETDQYGTLLVARGGEIECVEPTSSTVGTKIKVENLFFNTPVRLKY
MKSQQAELSHIVDVMNRLSLAHPEIAFTLINDGKKMTQTVGTGNLRQAIAGVYGLTTAKKMIEISASNLDFEVSGYISLP
ELTRANRNYITILINGRYIKNFLLNRAILDGYGSKLMVGRFPIAVIAIQIDPYLADVNVHPTKQEVRISKERELMVLISQ
AIAASLKEYDLIPDALENLAKSTINRVSKPEQTSLPLKENRLYYDQGRTDFFVKPQVSEDRPSFEKTDQLAQQPVAPDMP
DSRTVSIKFAERQAPSYDQLDHPELDQASMERALEKLDREGISTFPELEYFGQMHGTYLFAQGNGGLYIIDQHAAQERVK
YEYYRDKIGDVDDSQQQLLVPYIFEFPADDMLRLQQRMSLLEEVGIFLEEYGANQFILREHPIWLKEEEIESGVYEMCDM
LLLTKEVSIKKYRAELAIMMSCKRSIKANHSLDDYSARDLIFQLSQCNNPYNCPHGRPVLVNFTKSDMEKMFRRIQENHT
SLRELGKY

Nucleotide


Download         Length: 1947 bp        

>NTDB_id=396982 FOC71_RS01355 WP_037584706.1 256186..258132(-) (hexB) [Streptococcus intermedius strain FDAARGOS_769]
ATGTCAAAAATTATAGAATTACCAGAAAAACTTGCCAATCAGATTGCAGCAGGTGAGGTCATCGAGCGTCCTAGTAGTGT
GGTCAAGGAGTTGATAGAAAACTCCATTGATGCTGGTGCCACTCAGATTATAGTTGAGATTGAAGAAGCAGGTCTCAAGA
GTATTCAAGTCATTGATAATGGCGAAGGAATTGAGCATGAGGAAGTTCCCTTAGCTTTGCGTCGGCATGCGACGAGTAAG
ATTAAGAAACAAGCCGACCTTTTTCGAATTCGGACGTTGGGTTTTCGCGGTGAGGCCCTTCCATCTATCGCTTCCGTTTC
ATGTTTGACGATTGAAACTGCAACAGAGACAGATCAATATGGTACTCTCTTGGTAGCCCGAGGTGGTGAAATTGAGTGTG
TAGAACCAACGAGCAGCACTGTCGGAACAAAAATCAAAGTCGAAAATCTCTTTTTCAATACACCTGTTCGCTTGAAATAT
ATGAAAAGTCAGCAAGCCGAATTATCTCATATTGTAGATGTGATGAATCGTTTAAGTTTAGCCCATCCGGAGATTGCTTT
TACTCTAATAAATGACGGTAAAAAAATGACACAAACAGTAGGAACAGGGAATCTACGCCAAGCGATTGCTGGTGTTTATG
GACTGACAACGGCAAAAAAAATGATTGAGATTTCAGCTTCTAATCTGGATTTTGAAGTATCAGGCTATATTAGCCTGCCA
GAACTAACACGAGCTAATCGTAATTATATCACGATTCTCATCAATGGTCGCTATATTAAGAATTTCTTGCTCAATCGAGC
TATCCTTGATGGCTATGGTAGTAAGCTCATGGTGGGGCGTTTTCCGATTGCAGTGATTGCTATTCAGATTGATCCTTACC
TTGCTGATGTCAATGTTCATCCCACTAAGCAAGAAGTACGGATCTCAAAAGAGCGAGAGCTTATGGTCTTGATTTCACAA
GCGATTGCTGCGAGTCTAAAAGAGTATGATTTGATTCCAGATGCTTTGGAGAATTTAGCCAAATCAACTATTAATCGAGT
AAGTAAGCCTGAACAGACTAGCCTACCACTAAAGGAGAACCGACTTTATTACGACCAAGGAAGAACCGATTTCTTTGTGA
AACCACAAGTGTCAGAAGATCGACCTTCTTTTGAGAAAACTGACCAATTAGCTCAACAACCCGTTGCTCCAGATATGCCT
GATTCCAGAACAGTCTCTATTAAATTTGCAGAAAGGCAGGCGCCTTCTTATGACCAACTGGATCATCCTGAGTTAGATCA
AGCTAGTATGGAGAGAGCTTTAGAGAAGCTAGATAGAGAAGGAATATCAACCTTTCCAGAGTTGGAGTATTTCGGTCAAA
TGCACGGAACCTATCTCTTTGCACAAGGAAATGGTGGTCTTTATATTATTGACCAGCATGCGGCTCAAGAACGGGTCAAG
TATGAATATTATAGGGACAAAATAGGAGATGTAGATGACAGTCAGCAGCAGCTTTTGGTGCCTTATATTTTTGAATTTCC
GGCAGACGATATGCTGCGACTTCAACAACGAATGTCTCTTTTGGAAGAAGTGGGTATTTTCCTAGAAGAATATGGAGCCA
ATCAATTTATTTTGCGTGAACATCCTATTTGGCTCAAAGAAGAGGAAATTGAGTCAGGTGTCTATGAAATGTGTGATATG
CTGCTTTTGACCAAGGAAGTCTCTATTAAGAAATATCGTGCAGAGTTAGCTATTATGATGAGCTGTAAACGTTCTATTAA
GGCCAATCATAGCTTAGATGACTACTCGGCACGTGATTTAATTTTCCAACTATCACAATGCAACAATCCTTATAACTGTC
CACATGGTCGACCAGTCTTGGTTAACTTTACCAAGTCGGATATGGAAAAAATGTTTCGCCGCATTCAGGAAAATCATACT
AGCCTACGGGAGTTGGGTAAGTATTAA

Domains

Predicted by InterProScan.

MutL C terminal dimerisation domain (MutL_C)

(450-592)

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-326)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

75.422

100

0.758

Multiple sequence alignment