Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   HPM96_RS06470 Genome accession   NZ_CP053852
Coordinates   1314218..1316239 (+) Length   673 a.a.
NCBI ID   WP_000042532.1    Uniprot ID   B7NNK9
Organism   Escherichia coli strain CE1628     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1309218..1321239
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HPM96_RS06450 (HPM96_06445) bioB 1310036..1311076 (+) 1041 WP_000951213.1 biotin synthase BioB -
  HPM96_RS06455 (HPM96_06450) bioF 1311073..1312227 (+) 1155 WP_000118819.1 8-amino-7-oxononanoate synthase -
  HPM96_RS06460 (HPM96_06455) bioC 1312214..1312969 (+) 756 WP_000214374.1 malonyl-ACP O-methyltransferase BioC -
  HPM96_RS06465 (HPM96_06460) bioD 1312962..1313639 (+) 678 WP_000044856.1 dethiobiotin synthase -
  HPM96_RS06470 (HPM96_06465) uvrB 1314218..1316239 (+) 2022 WP_000042532.1 excinuclease ABC subunit UvrB Machinery gene
  HPM96_RS06475 (HPM96_06470) yvcK 1316277..1317185 (-) 909 WP_001361290.1 uridine diphosphate-N-acetylglucosamine-binding protein YvcK -
  HPM96_RS06480 (HPM96_06475) moaA 1317582..1318571 (+) 990 WP_001295301.1 GTP 3',8-cyclase MoaA -
  HPM96_RS06485 (HPM96_06480) moaB 1318593..1319105 (+) 513 WP_000084639.1 molybdenum cofactor biosynthesis protein B -
  HPM96_RS06490 (HPM96_06485) moaC 1319108..1319593 (+) 486 WP_000080883.1 cyclic pyranopterin monophosphate synthase MoaC -
  HPM96_RS06495 (HPM96_06490) moaD 1319586..1319831 (+) 246 WP_000598612.1 molybdopterin synthase sulfur carrier subunit -
  HPM96_RS06500 (HPM96_06495) moaE 1319833..1320285 (+) 453 WP_000852287.1 molybdopterin synthase catalytic subunit MoaE -
  HPM96_RS06505 (HPM96_06500) ybhL 1320422..1321126 (+) 705 WP_001361291.1 Bax inhibitor-1/YccA family protein -

Sequence

Protein


Download         Length: 673 a.a.        Molecular weight: 76212.03 Da        Isoelectric Point: 4.8825

>NTDB_id=395859 HPM96_RS06470 WP_000042532.1 1314218..1316239(+) (uvrB) [Escherichia coli strain CE1628]
MSKPFKLNSAFKPSGDQPEAIRRLEEGLEDGLAHQTLLGVTGSGKTFTIANVIADLQRPTMVLAPNKTLAAQLYGEMKEF
FPENAVEYFVSYYDYYQPEAYVPSSDTFIEKDASVNEHIEQMRLSATKAMLERRDVVVVASVSAIYGLGDPDLYLKMMLH
LTVGMIIDQRAILRRLAELQYARNDQAFQRGTFRVRGEVIDIFPAESDDIALRVELFDEEVERLSLFDPLTGQIVSTIPR
FTIYPKTHYVTPRERIVQAMEEIKEELAARRKVLLENNKLLEEQRLTQRTQFDLEMMNELGYCSGIENYSRFLSGRGPGE
PPPTLFDYLPADGLLVVDESHVTIPQIGGMYRGDRARKETLVEYGFRLPSALDNRPLKFEEFEALAPQTIYVSATPGNYE
LEKSGGDVVDQVVRPTGLLDPIIEVRPVATQVDDLLSEIRQRAAINERVLVTTLTKRMAEDLTEYLEEHGERVRYLHSDI
DTVERMEIIRDLRLGEFDVLVGINLLREGLDMPEVSLVAILDADKEGFLRSERSLIQTIGRAARNVNGKAILYGDKITPS
MAKAIGETERRREKQQKYNEEHGITPQGLNKKVVDILALGQNIAKTKAKGRGKSRPIVEPDNVPMDMSPKALQQKIHELE
GLMMQHAQNLEFEEAAQIRDQLHQLRDLFIAAS

Nucleotide


Download         Length: 2022 bp        

>NTDB_id=395859 HPM96_RS06470 WP_000042532.1 1314218..1316239(+) (uvrB) [Escherichia coli strain CE1628]
ATGAGTAAACCGTTCAAACTGAATTCCGCTTTTAAACCTTCTGGCGATCAGCCAGAGGCGATTCGACGTCTCGAAGAGGG
GCTGGAAGATGGCCTGGCGCACCAGACGTTACTTGGAGTGACTGGCTCCGGGAAAACCTTCACCATTGCCAATGTCATTG
CTGACCTTCAGCGCCCTACCATGGTACTTGCGCCCAACAAAACGCTGGCGGCCCAGTTGTATGGCGAAATGAAAGAATTC
TTCCCGGAAAACGCGGTGGAATATTTCGTCTCCTACTACGACTACTATCAGCCGGAAGCCTATGTACCGAGTTCCGACAC
CTTCATTGAGAAAGATGCCTCGGTAAACGAACATATCGAGCAGATGCGTTTGTCCGCCACCAAAGCGATGCTGGAGCGGC
GTGATGTGGTTGTGGTGGCATCGGTTTCCGCGATTTATGGTCTGGGCGATCCTGATTTATATCTCAAGATGATGCTCCAT
CTCACGGTCGGTATGATTATCGATCAGCGCGCGATTCTGCGCCGACTGGCGGAGCTGCAATACGCTCGTAATGATCAGGC
ATTCCAGCGCGGTACTTTCCGCGTTCGTGGTGAGGTGATAGATATCTTCCCGGCAGAATCGGATGACATTGCACTTCGCG
TGGAACTGTTTGACGAGGAAGTGGAACGATTGTCGTTATTTGACCCGCTGACCGGGCAGATTGTTTCCACTATTCCACGT
TTTACCATCTACCCGAAAACGCACTACGTCACGCCGCGCGAGCGCATCGTACAGGCGATGGAAGAGATCAAAGAAGAACT
GGCCGCCAGACGCAAAGTGCTGTTGGAGAACAACAAGTTGCTTGAAGAGCAGCGGCTGACCCAGCGTACCCAGTTTGATC
TGGAGATGATGAACGAACTGGGGTATTGCTCGGGCATTGAAAACTACTCACGCTTCCTCTCCGGCCGTGGACCAGGTGAG
CCACCGCCGACGCTGTTTGATTACCTGCCTGCCGATGGGCTGTTGGTCGTCGATGAATCTCACGTCACCATTCCACAAAT
TGGCGGCATGTATCGCGGTGACCGGGCGCGTAAAGAGACACTGGTGGAGTATGGCTTCCGCCTGCCATCAGCGCTGGATA
ACCGTCCGCTTAAGTTTGAAGAGTTCGAAGCATTAGCGCCGCAAACCATCTATGTTTCGGCGACGCCGGGTAATTACGAG
CTGGAAAAATCCGGCGGCGATGTGGTGGATCAGGTGGTGCGTCCAACAGGCTTACTTGACCCGATTATTGAAGTGCGTCC
GGTAGCGACACAGGTGGATGATCTTCTATCGGAGATTCGTCAGCGAGCGGCAATTAACGAACGCGTACTGGTTACAACTC
TGACCAAGCGGATGGCGGAAGATCTCACTGAATATCTCGAAGAACACGGTGAGCGCGTGCGTTATCTTCACTCAGATATC
GACACCGTCGAACGTATGGAGATTATCCGCGACTTGCGTCTGGGTGAGTTCGACGTATTGGTAGGGATCAACTTACTGCG
CGAAGGTCTGGATATGCCGGAAGTGTCGCTGGTGGCGATCCTCGACGCTGACAAAGAAGGCTTCCTGCGTTCCGAACGTT
CGTTGATCCAGACCATTGGTCGTGCGGCACGTAACGTTAACGGTAAAGCGATTCTCTACGGCGATAAGATCACCCCATCA
ATGGCGAAAGCGATTGGCGAAACCGAACGTCGCCGCGAGAAACAGCAGAAGTACAACGAGGAACACGGCATTACGCCGCA
AGGCTTGAACAAGAAAGTGGTCGATATCCTGGCGCTGGGGCAGAACATTGCCAAAACCAAAGCGAAGGGCAGAGGAAAAT
CGCGCCCGATTGTTGAGCCGGATAATGTGCCGATGGATATGTCGCCTAAAGCGTTGCAGCAGAAGATCCATGAACTGGAA
GGGTTGATGATGCAACACGCGCAGAATCTGGAGTTCGAAGAAGCGGCGCAAATTCGTGACCAGTTGCATCAGTTGCGTGA
TTTGTTTATTGCCGCGTCGTGA

Domains

Predicted by InterProScan.

UvrB interaction domain (UvrB_inter)

(159-249)

Ultra-violet resistance protein B (UvrB)

(552-593)

UvrB/uvrC motif (UVR)

(634-667)

Type III restriction enzyme, res subunit (ResIII)

(13-92)

Helicase conserved C-terminal domain (Helicase_C)

(436-544)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB B7NNK9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae TIGR4

56.372

99.108

0.559
  uvrB Streptococcus pneumoniae R6

56.222

99.108

0.557
  uvrB Streptococcus pneumoniae D39

56.222

99.108

0.557

Multiple sequence alignment