Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   SGGB_RS07950 Genome accession   NC_017576
Coordinates   1604902..1606254 (-) Length   450 a.a.
NCBI ID   WP_009854645.1    Uniprot ID   A0A1I7GS68
Organism   Streptococcus gallolyticus subsp. gallolyticus ATCC 43143     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1599902..1611254
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SGGB_RS07940 (SGGB_1547) rnc 1602876..1603562 (-) 687 WP_009854642.1 ribonuclease III -
  SGGB_RS07945 (SGGB_1549) vicX 1604092..1604901 (-) 810 WP_009854644.1 MBL fold metallo-hydrolase Regulator
  SGGB_RS07950 (SGGB_1550) vicK 1604902..1606254 (-) 1353 WP_009854645.1 cell wall metabolism sensor histidine kinase VicK Regulator
  SGGB_RS07955 (SGGB_1551) yycF 1606247..1606957 (-) 711 WP_009854646.1 response regulator YycF -
  SGGB_RS07960 (SGGB_1552) - 1607262..1608026 (+) 765 WP_009854647.1 amino acid ABC transporter ATP-binding protein -
  SGGB_RS07965 (SGGB_1553) - 1608037..1608849 (+) 813 WP_014620198.1 transporter substrate-binding domain-containing protein -
  SGGB_RS07970 (SGGB_1554) - 1608866..1609570 (+) 705 WP_009854649.1 amino acid ABC transporter permease -
  SGGB_RS07975 (SGGB_1555) - 1609582..1610229 (+) 648 WP_012962237.1 amino acid ABC transporter permease -
  SGGB_RS07980 (SGGB_1556) - 1610321..1610929 (-) 609 WP_009854651.1 TVP38/TMEM64 family protein -

Sequence

Protein


Download         Length: 450 a.a.        Molecular weight: 51520.54 Da        Isoelectric Point: 4.6944

>NTDB_id=39568 SGGB_RS07950 WP_009854645.1 1604902..1606254(-) (vicK) [Streptococcus gallolyticus subsp. gallolyticus ATCC 43143]
MNDTMLQNLTYFEQAILFLLAFVAVYFVYLAIRDYRTSVNIRRLSGKVRELITGKYTEDIIIEKDRDLAELADQLNDLST
VFRLAQENLAQEKNRLASILSYMTDGVLATDRAGNITMINQTAQQQLNLEREEALQMNIVDILGSDSTYSYHDLVSKTPE
IVLNRRDETGEFITLRIRFALNRRDSGFISGLIAVLHDTTEQEKEDRERRLFVSNVSHELRTPLTSVKSYLEALDEGALK
EDIAPSFIKVSLDETNRMIRMISDLLNLSRIDNQTVQLEVEMTNFTAFMTSILNRFDQIKSQHTISGKQYEIVRDYPIKS
IWLEIDPDKMTQVLDNILNNAIKYSPDGGKITVSMKTTETQLIISISDEGLGIPKKDLPLIFDRFYRVDKARSRAQGGSG
LGLAIAKEIVKQHKGFIWAQSTYGKGSTFTIVLPYEKDSEIYDEWEDEEE

Nucleotide


Download         Length: 1353 bp        

>NTDB_id=39568 SGGB_RS07950 WP_009854645.1 1604902..1606254(-) (vicK) [Streptococcus gallolyticus subsp. gallolyticus ATCC 43143]
ATGAATGATACAATGTTACAAAATTTAACTTATTTTGAACAAGCCATTCTCTTTCTTTTAGCATTTGTCGCAGTTTATTT
TGTTTATTTAGCGATAAGAGATTATCGAACTTCTGTTAATATTCGACGTTTGAGTGGTAAAGTGCGAGAGCTTATCACAG
GAAAATACACAGAAGATATTATTATTGAAAAAGATAGAGACTTAGCTGAGTTAGCTGACCAATTAAATGATTTGTCAACA
GTCTTTCGTTTAGCGCAGGAAAATTTGGCACAAGAAAAGAATCGTTTGGCGAGTATCTTATCTTATATGACAGACGGTGT
CTTGGCGACTGACCGTGCTGGAAATATCACAATGATTAATCAGACCGCGCAACAACAACTCAATTTAGAGCGTGAAGAAG
CTTTGCAGATGAATATTGTTGATATTTTAGGTTCTGATAGCACTTATAGTTATCATGATTTGGTGTCAAAAACACCTGAA
ATTGTCTTGAACCGTCGTGACGAAACAGGTGAATTTATCACTTTACGTATTCGCTTTGCTCTAAATCGTCGTGATAGTGG
CTTTATTTCAGGGTTGATTGCTGTTTTACATGACACAACCGAACAAGAAAAAGAAGACCGTGAGCGTCGTCTTTTCGTTT
CTAACGTTAGTCATGAATTGCGAACACCATTAACATCTGTAAAATCTTATCTGGAAGCTTTAGATGAAGGAGCGCTCAAA
GAAGACATTGCGCCAAGTTTTATCAAAGTATCTTTAGATGAAACAAACCGCATGATTCGTATGATTTCAGACTTGCTTAA
CTTATCGCGTATTGATAATCAGACGGTTCAATTGGAAGTGGAAATGACAAATTTCACAGCATTTATGACATCAATTCTTA
ACCGTTTTGATCAAATTAAAAGCCAACATACAATTAGCGGAAAACAGTATGAGATTGTCAGGGATTATCCTATTAAATCA
ATCTGGCTTGAAATTGACCCTGATAAGATGACGCAGGTTTTGGATAATATCCTTAATAATGCTATCAAATATTCACCAGA
TGGTGGAAAAATCACAGTTAGCATGAAAACGACGGAAACACAGTTGATTATCTCAATCTCTGATGAAGGGCTTGGTATTC
CTAAGAAAGATTTGCCATTGATTTTCGACCGTTTCTATCGTGTGGATAAGGCTCGAAGTCGTGCCCAAGGTGGTTCAGGA
CTTGGCTTAGCTATCGCAAAAGAAATTGTCAAACAACATAAAGGTTTTATTTGGGCACAAAGTACTTACGGAAAAGGGTC
GACCTTTACGATTGTACTTCCTTACGAAAAAGATTCTGAAATTTATGATGAATGGGAGGATGAAGAAGAGTAG

Domains

Predicted by InterProScan.

PAS fold (PAS)

(95-189)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(326-436)

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1I7GS68

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

75.663

92.222

0.698
  micB Streptococcus pneumoniae Cp1015

66.038

94.222

0.622

Multiple sequence alignment