Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   HO400_RS05100 Genome accession   NZ_CP053597
Coordinates   1111414..1112046 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain T7Express_LysY     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1106414..1117046
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HO400_RS05075 (HO400_05075) yhfG 1106546..1106713 (+) 168 WP_000736861.1 YhfG family protein -
  HO400_RS05080 (HO400_05080) fic 1106703..1107305 (+) 603 WP_000502522.1 putative adenosine monophosphate-protein transferase Fic -
  HO400_RS05085 (HO400_05085) pabA 1107337..1107900 (+) 564 WP_000601847.1 aminodeoxychorismate synthase component 2 -
  HO400_RS05090 (HO400_05090) argD 1107986..1109206 (+) 1221 WP_000963792.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  HO400_RS05095 (HO400_05095) yhfK 1109273..1111363 (-) 2091 WP_012775971.1 YccS/YhfK family putative transporter -
  HO400_RS05100 (HO400_05100) crp 1111414..1112046 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  HO400_RS05105 (HO400_05105) yhfA 1112348..1112752 (+) 405 WP_001148908.1 OsmC family protein -
  HO400_RS05110 (HO400_05110) prkB 1112807..1113676 (-) 870 WP_001274680.1 phosphoribulokinase -
  HO400_RS05115 (HO400_05115) yheU 1113730..1113948 (-) 219 WP_000907085.1 YheU family protein -
  HO400_RS05120 (HO400_05120) yheT 1113942..1114964 (-) 1023 WP_000057356.1 hydrolase -
  HO400_RS05125 (HO400_05125) yheS 1114964..1116877 (-) 1914 WP_000634798.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=392224 HO400_RS05100 WP_000242755.1 1111414..1112046(-) (crp) [Escherichia coli strain T7Express_LysY]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=392224 HO400_RS05100 WP_000242755.1 1111414..1112046(-) (crp) [Escherichia coli strain T7Express_LysY]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTTTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATTGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment