Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   HLY11_RS17800 Genome accession   NZ_CP053258
Coordinates   3804569..3805228 (-) Length   219 a.a.
NCBI ID   WP_171460349.1    Uniprot ID   -
Organism   Escherichia coli strain GF4-3     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 3799569..3810228
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HLY11_RS17775 (HLY11_17780) - 3799773..3800525 (-) 753 WP_000619462.1 GntR family transcriptional regulator -
  HLY11_RS17780 (HLY11_17785) - 3800812..3802143 (+) 1332 WP_171460347.1 MFS transporter -
  HLY11_RS17785 (HLY11_17790) ygiN 3802187..3802501 (-) 315 WP_000958598.1 putative quinol monooxygenase -
  HLY11_RS17790 (HLY11_17795) mdaB 3802532..3803113 (-) 582 WP_000065430.1 NADPH:quinone oxidoreductase MdaB -
  HLY11_RS17795 (HLY11_17800) qseC 3803223..3804572 (-) 1350 WP_171460348.1 quorum sensing histidine kinase QseC -
  HLY11_RS17800 (HLY11_17805) ciaR 3804569..3805228 (-) 660 WP_171460349.1 quorum sensing response regulator transcription factor QseB Regulator
  HLY11_RS17805 (HLY11_17810) ygiW 3805380..3805772 (+) 393 WP_000712658.1 OB fold stress tolerance protein YgiW -
  HLY11_RS17810 (HLY11_17815) ygiV 3805825..3806307 (+) 483 WP_171460350.1 GyrI-like domain-containing protein -
  HLY11_RS17815 (HLY11_17820) mqsR 3806512..3806808 (+) 297 WP_171460351.1 type II toxin-antitoxin system toxin MqsR -
  HLY11_RS17820 (HLY11_17825) mqsA 3806810..3807205 (+) 396 WP_000650107.1 type II toxin-antitoxin system antitoxin MqsA -
  HLY11_RS17825 (HLY11_17830) ygiS 3807338..3808945 (+) 1608 WP_171460352.1 ABC transporter substrate-binding protein -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24669.65 Da        Isoelectric Point: 6.9850

>NTDB_id=391237 HLY11_RS17800 WP_171460349.1 3804569..3805228(-) (ciaR) [Escherichia coli strain GF4-3]
MRILLIEDDMLIGDGIKTGLGKMGFSVDWFTQGRQGKEALYSAPYDAVILDLTLPGMDGRDILREWREKGQREPVLILTA
RDALAERVEGLRLGADDYLCKPFALIEVAARLEALMRRTNGQASNELRHGNVMLDPGKRIATLAGEPLILKPKEFALLEL
LMRNAGRVLPRKLIEEKLYTWDEEVTSNAVEVHVHHLRRKLGSDFIRTVHGIGYTLGEK

Nucleotide


Download         Length: 660 bp        

>NTDB_id=391237 HLY11_RS17800 WP_171460349.1 3804569..3805228(-) (ciaR) [Escherichia coli strain GF4-3]
ATGCGAATTTTACTGATAGAAGATGACATGCTGATTGGCGACGGCATCAAAACTGGCCTTGGTAAAATGGGTTTTAGCGT
CGACTGGTTTACACAAGGTCGTCAGGGAAAAGAGGCGCTATATAGTGCGCCTTATGATGCGGTGATCCTGGATTTAACCT
TACCAGGCATGGATGGTCGCGATATTTTGCGCGAATGGCGAGAAAAAGGTCAGCGTGAGCCGGTACTGATCCTGACCGCG
CGCGATGCGTTAGCGGAACGTGTTGAGGGGCTGCGTCTGGGAGCTGACGATTATCTGTGTAAACCTTTTGCGTTGATAGA
AGTCGCCGCCAGGCTGGAAGCTCTGATGCGCCGAACCAACGGCCAGGCCAGCAACGAACTGCGCCACGGTAACGTCATGC
TCGACCCCGGCAAACGTATCGCCACGCTGGCTGGCGAACCCTTAATACTGAAACCAAAAGAATTTGCTCTGCTGGAATTA
CTGATGCGTAACGCTGGTCGGGTACTGCCGCGCAAACTGATTGAAGAGAAACTGTATACCTGGGACGAAGAGGTCACCAG
TAATGCCGTTGAAGTGCATGTGCATCATCTGCGACGCAAACTCGGCAGTGATTTTATTCGTACCGTGCATGGTATTGGCT
ACACATTAGGTGAGAAATGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(3-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-216)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

36.771

100

0.374
  ciaR Streptococcus pneumoniae D39

36.771

100

0.374
  ciaR Streptococcus pneumoniae R6

36.771

100

0.374
  ciaR Streptococcus pneumoniae TIGR4

36.771

100

0.374
  ciaR Streptococcus mutans UA159

35.874

100

0.365