Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   HHJ54_RS21795 Genome accession   NZ_CP053245
Coordinates   4549254..4549910 (-) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain SCU-485     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 4544254..4554910
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HHJ54_RS21765 (HHJ54_21750) yecA 4545506..4546171 (-) 666 WP_000847877.1 UPF0149 family protein YecA -
  HHJ54_RS21785 (HHJ54_21770) pgsA 4546820..4547368 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  HHJ54_RS21790 (HHJ54_21775) uvrC 4547425..4549257 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  HHJ54_RS21795 (HHJ54_21780) letA 4549254..4549910 (-) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  HHJ54_RS21800 (HHJ54_21785) yecU 4550206..4550382 (+) 177 WP_001307856.1 protein YecU -
  HHJ54_RS21805 (HHJ54_21790) yecF 4550369..4550593 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  HHJ54_RS21810 (HHJ54_21795) sdiA 4550661..4551383 (-) 723 WP_001154255.1 transcriptional regulator SdiA -
  HHJ54_RS21815 (HHJ54_21800) tcyN 4551613..4552365 (-) 753 WP_001273000.1 L-cystine ABC transporter ATP-binding protein TcyN -
  HHJ54_RS21820 (HHJ54_21805) tcyL 4552362..4553030 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  HHJ54_RS21825 (HHJ54_21810) dcyD 4553045..4554031 (-) 987 WP_001128236.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=390961 HHJ54_RS21795 WP_000611328.1 4549254..4549910(-) (letA) [Escherichia coli strain SCU-485]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=390961 HHJ54_RS21795 WP_000611328.1 4549254..4549910(-) (letA) [Escherichia coli strain SCU-485]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAATGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGAGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482

Multiple sequence alignment