Detailed information NTG0039086

Bioinformatically predicted

Overview

• Name: comP
• Type: Machinery gene
• Locus tag: NLA_RS10115
• Genome accession: NC_014752
• Coordinates: 2102123..2102572 (-)
• Length: 149 a.a.
• NCBI ID: WP_003710616.1
• Uniprot ID: A0A378VPN9
• Organism: Neisseria lactamica 020-06
• Function: DNA binding; DNA uptake; receptor of DNA uptake sequence (DUS) (predicted from homology) DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
Genomic island	2092338..2102959	2102123..2102572	within	0

Gene organization within MGE regions

Location: 2092338..2102959

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NLA_RS10080 (NLA_19500)	-	2092455..2093388 (+)	934	Protein_2018	HindVP family restriction endonuclease	-
NLA_RS10085 (NLA_19510)	-	2093385..2094377 (+)	993	WP_013449595.1	DNA cytosine methyltransferase	-
NLA_RS10090 (NLA_19520)	-	2094485..2097397 (+)	2913	WP_013449596.1	DUF3418 domain-containing protein	-
NLA_RS10095 (NLA_19530)	-	2097445..2099925 (+)	2481	WP_013449597.1	SIR2 family protein	-
NLA_RS10105 (NLA_19540)	-	2100046..2101052 (+)	1007	Protein_2022	IS5 family transposase	-
NLA_RS14110	-	2101837..2102116 (+)	280	Protein_2023	5'-nucleotidase	-
NLA_RS10115 (NLA_19560)	comP	2102123..2102572 (-)	450	WP_003710616.1	type IV pilin protein	Machinery gene

Sequence

Protein

• Length: 149 a.a.
• Molecular weight: 16836.73 Da
• Isoelectric Point: 9.6170

>NTDB_id=39086 NLA_RS10115 WP_003710616.1 2102123..2102572(-) (comP) [Neisseria lactamica 020-06]
MTDNRGFTLVELISVVLILSVLALIVYPSYRNYVEKAKINAVRAALLENAHFMEKFYLQNGRFKQTSTKWPSLPIKEAEG
FCIRLNGIARGALDSKFMLKAVAIDKDKNPFIIKMNENSVTFICKKSASSCDDGLDYFKGNDKDCKLLK

Nucleotide

• Length: 450 bp

>NTDB_id=39086 NLA_RS10115 WP_003710616.1 2102123..2102572(-) (comP) [Neisseria lactamica 020-06]
ATGACTGATAATCGGGGGTTTACGCTGGTTGAATTAATATCAGTGGTCTTGATATTGTCTGTACTTGCTTTAATTGTTTA
TCCGAGCTATCGCAATTATGTTGAGAAAGCAAAGATAAATGCAGTGCGGGCGGCTTTGTTAGAAAATGCACATTTTATGG
AAAAGTTTTATCTGCAGAATGGGAGGTTTAAACAAACATCTACTAAATGGCCAAGTTTGCCGATTAAAGAGGCAGAAGGC
TTTTGTATCCGTTTGAATGGAATTGCGCGTGGGGCTTTAGATAGTAAGTTCATGTTAAAGGCGGTAGCCATAGATAAAGA
TAAAAATCCTTTTATTATTAAGATGAATGAGAATTCGGTAACCTTTATTTGCAAGAAGTCCGCCAGTTCGTGCGATGACG
GACTAGATTATTTTAAAGGTAACGATAAGGACTGCAAGTTACTTAAGTAG

Domains

Predicted by InterproScan.

• Type IV minor pilin ComP, DNA uptake sequence receptor (ComP_DUS) (28-107)

• Prokaryotic N-terminal methylation motif (N_methyl) (1-27)

3D structure

• AlphaFold DB: A0A378VPN9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comP	Neisseria gonorrhoeae MS11	98.658	100	0.987
comP	Neisseria meningitidis 8013	97.987	100	0.98
comP	Neisseria subflava NJ9703	48.98	98.658	0.483