Detailed information NTG0390592

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: F8M43_RS18525
• Genome accession: NZ_CP044498
• Coordinates: 3541975..3543132 (-)
• Length: 385 a.a.
• NCBI ID: WP_003227983.1
• Uniprot ID: A0A199WDV9
• Organism: Bacillus subtilis strain ms-2
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3536975..3548132

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
F8M43_RS18495	yvyF	3537228..3537647 (-)	420	WP_003227995.1	TIGR03826 family flagellar region protein	-
F8M43_RS18500	comFC	3537721..3538443 (-)	723	WP_038427947.1	comF operon protein ComFC	Machinery gene
F8M43_RS18505	comFB	3538407..3538703 (-)	297	WP_015483764.1	late competence protein ComFB	-
F8M43_RS18510	comFA	3538763..3540154 (-)	1392	WP_038427948.1	ATP-dependent helicase ComFA	Machinery gene
F8M43_RS18515	fakBA	3540260..3541105 (-)	846	WP_003244125.1	DegV family protein	-
F8M43_RS18520	degU	3541203..3541892 (-)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
F8M43_RS18525	degS	3541975..3543132 (-)	1158	WP_003227983.1	two-component sensor histidine kinase DegS	Regulator
F8M43_RS18530	yvyE	3543349..3544002 (+)	654	WP_003227979.1	YigZ family protein	-
F8M43_RS18535	tagV	3544002..3545177 (+)	1176	WP_015251114.1	polyisoprenyl-teichoic acid--peptidoglycan teichoic acid transferase TagV	-
F8M43_RS18540	tagO	3545250..3546326 (-)	1077	WP_003227975.1	MraY family glycosyltransferase	-
F8M43_RS18545	tuaH	3546471..3547664 (-)	1194	WP_072692828.1	glycosyltransferase family 1 protein	-

Sequence

Protein

• Length: 385 a.a.
• Molecular weight: 44957.76 Da
• Isoelectric Point: 6.2957

>NTDB_id=390592 F8M43_RS18525 WP_003227983.1 3541975..3543132(-) (degS) [Bacillus subtilis strain ms-2]
MNKTKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVQTRHARNRLSEVSR
NFHRFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLREVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGAEDGFQEIKNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGETEDQRLAPQFEVALFRLAQEAVSNALKHSESEEITVKVEI
TKDFVILMIKDNGKGFDLKEAKEKKNKSFGLLGMKERVDLLEGTMTIDSKIGLGTFIMIKVPLSL

Nucleotide

• Length: 1158 bp

>NTDB_id=390592 F8M43_RS18525 WP_003227983.1 3541975..3543132(-) (degS) [Bacillus subtilis strain ms-2]
ATGAATAAAACAAAGATGGATTCCAAAGTGCTGGATTCTATTTTGATGAAGATGCTGAAAACCGTTGACGGGAGCAAGGA
CGAAGTTTTTCAAATCGGGGAGCAGTCACGCCAGCAGTATGAACAGCTGGTCGAAGAACTGAAACAAATTAAACAGCAGG
TGTATGAAGTGATTGAGCTTGGCGATAAACTTGAAGTGCAAACTCGCCATGCGAGAAACCGTTTATCCGAGGTCAGCCGT
AATTTTCATAGATTCAGTGAAGAGGAAATCCGCAATGCTTATGAAAAAGCCCATAAGCTGCAGGTAGAATTGACGATGAT
CCAGCAGCGTGAGAAGCAATTGCGCGAACGGCGGGACGATTTGGAGCGCAGATTGCTAGGGCTTCAGGAAATCATTGAGC
GGTCAGAATCATTAGTAAGCCAAATTACAGTTGTGCTCAACTACTTGAATCAGGATTTGCGCGAAGTTGGACTGCTTCTT
GCTGATGCTCAGGCAAAACAGGATTTCGGCTTAAGAATCATTGAGGCGCAGGAAGAAGAGAGAAAAAGAGTCTCAAGAGA
AATCCATGACGGACCCGCTCAAATGCTGGCGAATGTTATGATGAGATCGGAATTAATCGAGCGGATTTTCCGTGACCGGG
GCGCAGAGGACGGATTCCAAGAAATTAAAAATCTACGCCAAAATGTTCGGAATGCCCTTTACGAAGTGAGAAGGATTATA
TATGATTTAAGACCGATGGCCCTTGATGACCTAGGCCTGATTCCAACTTTAAGAAAATATCTATATACAACCGAGGAATA
TAACGGGAAGGTCAAAATACATTTTCAGTGCATTGGAGAAACAGAGGATCAGAGGCTAGCGCCTCAGTTTGAGGTTGCGC
TCTTCAGGCTCGCACAGGAAGCTGTGTCTAATGCGCTAAAGCATTCTGAATCTGAAGAAATTACAGTCAAAGTTGAGATC
ACAAAGGATTTTGTGATTTTAATGATAAAAGATAACGGTAAAGGGTTCGACCTGAAGGAAGCGAAAGAGAAGAAAAACAA
ATCATTCGGCTTGCTGGGCATGAAAGAAAGAGTAGATTTATTGGAAGGAACGATGACAATAGATTCGAAAATAGGTCTTG
GGACATTTATTATGATTAAGGTTCCGTTATCTCTTTGA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (180-248)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

3D structure

• AlphaFold DB: A0A199WDV9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	100	100	1