Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   F8B64_RS00180 Genome accession   NZ_CP044497
Coordinates   39420..40094 (-) Length   224 a.a.
NCBI ID   WP_005647998.1    Uniprot ID   Q4QLV0
Organism   Haemophilus influenzae strain PittGG     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 34420..45094
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  F8B64_RS00160 (F8B64_00160) hinT 36124..36474 (+) 351 WP_005669644.1 purine nucleoside phosphoramidase -
  F8B64_RS00165 (F8B64_00165) - 36474..36824 (+) 351 WP_005647993.1 YcfL family protein -
  F8B64_RS00170 (F8B64_00170) nagZ 36828..37880 (+) 1053 WP_041174823.1 beta-N-acetylhexosaminidase -
  F8B64_RS00175 (F8B64_00175) rlmC 37877..39055 (+) 1179 WP_012055322.1 23S rRNA (uracil(747)-C(5))-methyltransferase RlmC -
  F8B64_RS00180 (F8B64_00180) crp 39420..40094 (-) 675 WP_005647998.1 cAMP-activated global transcriptional regulator CRP Regulator
  F8B64_RS00185 (F8B64_00185) - 40079..40330 (-) 252 Protein_34 YheU family protein -
  F8B64_RS00190 (F8B64_00190) slmA 40352..41008 (-) 657 WP_005648000.1 nucleoid occlusion factor SlmA -
  F8B64_RS00195 (F8B64_00195) dut 41012..41467 (-) 456 WP_005631431.1 dUTP diphosphatase -
  F8B64_RS00200 (F8B64_00200) coaBC 41515..42717 (-) 1203 WP_012055320.1 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC -
  F8B64_RS00205 (F8B64_00205) radC 42880..43545 (+) 666 WP_074039347.1 DNA repair protein RadC -
  F8B64_RS00210 (F8B64_00210) rpmB 43759..43995 (+) 237 WP_005542826.1 50S ribosomal protein L28 -
  F8B64_RS00215 (F8B64_00215) rpmG 44007..44177 (+) 171 WP_005613503.1 50S ribosomal protein L33 -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25151.85 Da        Isoelectric Point: 6.8375

>NTDB_id=390489 F8B64_RS00180 WP_005647998.1 39420..40094(-) (crp) [Haemophilus influenzae strain PittGG]
MSNELTEIDEVVTSSQEEATQRDPVLDWFLTHCHLHKYPAKSTLIHAGEDATTLYYVIKGSVMVSSKDDEGKEMILTYLG
AGQFFGEAGLFDEGSKRSAWVKTKTTCEIAEISYKKYRQLIQANPEILMFLTAQLARRLQNTSRQVTNLAFLDVAGRIAQ
TLMNLAKQPEAMTHPDGMQIKITRQEIGQMVGCSRETVGRIIKMLEDQNLIHAHGKTIVVYGAR

Nucleotide


Download         Length: 675 bp        

>NTDB_id=390489 F8B64_RS00180 WP_005647998.1 39420..40094(-) (crp) [Haemophilus influenzae strain PittGG]
ATGTCAAATGAATTAACCGAAATTGATGAAGTTGTAACCTCCTCTCAAGAAGAAGCAACTCAACGAGATCCCGTTTTAGA
TTGGTTTCTTACTCACTGCCATTTGCATAAGTATCCTGCAAAATCAACTTTAATTCATGCTGGGGAAGATGCGACCACGC
TGTATTATGTAATTAAAGGTTCTGTAATGGTATCTTCAAAAGATGATGAAGGCAAAGAGATGATCCTCACTTACTTAGGT
GCAGGACAATTTTTTGGCGAAGCGGGATTATTTGATGAAGGTTCAAAACGATCAGCTTGGGTAAAAACAAAAACAACATG
TGAAATTGCTGAAATTTCCTATAAGAAATATCGCCAGTTGATTCAGGCAAACCCTGAAATCTTAATGTTTCTCACTGCAC
AATTGGCAAGACGTTTGCAAAATACATCACGTCAAGTCACGAATTTGGCATTTTTAGACGTCGCAGGTCGCATCGCTCAA
ACTTTAATGAACTTAGCTAAACAGCCTGAAGCAATGACGCATCCTGATGGTATGCAAATCAAAATTACACGCCAAGAAAT
AGGGCAAATGGTGGGTTGTTCACGAGAAACTGTGGGGCGCATTATTAAGATGTTGGAGGATCAGAATCTTATCCACGCTC
ATGGAAAAACAATCGTTGTATATGGCGCAAGATAA

Domains

Predicted by InterproScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(36-124)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(156-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q4QLV0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Haemophilus influenzae Rd KW20

100

100

1
  crp Vibrio cholerae strain A1552

75.49

91.071

0.687
  crp Acinetobacter baumannii D1279779

48.705

86.161

0.42

Multiple sequence alignment