Detailed information    

insolico Bioinformatically predicted

Overview

Name   treR   Type   Regulator
Locus tag   HKM25_RS09395 Genome accession   NZ_CP053210
Coordinates   1851637..1852347 (+) Length   236 a.a.
NCBI ID   WP_000760673.1    Uniprot ID   A0A0H2URH4
Organism   Streptococcus pneumoniae strain 6A-10     
Function   regulate expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1846637..1857347
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HKM25_RS09380 (HKM25_1917) - 1847178..1847426 (-) 249 WP_000364990.1 YneF family protein -
  HKM25_RS09385 (HKM25_1918) treC 1847682..1849307 (-) 1626 WP_054362600.1 alpha,alpha-phosphotrehalase -
  HKM25_RS09390 (HKM25_1919) treP 1849485..1851452 (-) 1968 WP_054365875.1 PTS system trehalose-specific EIIBC component -
  HKM25_RS09395 (HKM25_1920) treR 1851637..1852347 (+) 711 WP_000760673.1 trehalose operon repressor Regulator
  HKM25_RS09400 - 1852502..1853837 (+) 1336 Protein_1878 ISL3 family transposase -
  HKM25_RS09405 (HKM25_1923) - 1853912..1854838 (-) 927 WP_001291293.1 ATP-binding cassette domain-containing protein -
  HKM25_RS09410 (HKM25_1924) amiE 1854849..1855916 (-) 1068 WP_000159555.1 ABC transporter ATP-binding protein Regulator
  HKM25_RS09415 (HKM25_1925) amiD 1855925..1856851 (-) 927 WP_000103700.1 oligopeptide ABC transporter permease OppC Regulator

Sequence

Protein


Download         Length: 236 a.a.        Molecular weight: 27607.78 Da        Isoelectric Point: 8.9698

>NTDB_id=390438 HKM25_RS09395 WP_000760673.1 1851637..1852347(+) (treR) [Streptococcus pneumoniae strain 6A-10]
MKKYQQLFKQIQETIQNETYAVGDFLPSEHDLMEQYQVSRDTVRKALSLLQEEGLIKKIRGQGSQVVKEETVNFPVSNLT
SYQELVKELGLRSKTNVVSLDKIIIDKKSSLITGFPEFRMVWKVVRQRVVDDLVSVLDTDYLDMELIPNLTRQIAEQSIY
SYIENGLKLLIDYAQKEITIDHSSDRDKILMDIGKDPYVVSIKSKVYLQDGRQFQFTESRHKLEKFRFVDFAKRKK

Nucleotide


Download         Length: 711 bp        

>NTDB_id=390438 HKM25_RS09395 WP_000760673.1 1851637..1852347(+) (treR) [Streptococcus pneumoniae strain 6A-10]
ATGAAGAAATACCAACAATTATTTAAGCAAATCCAAGAAACCATTCAAAACGAGACTTACGCTGTCGGAGATTTCCTTCC
TAGCGAGCACGACCTTATGGAGCAATATCAAGTGAGTCGTGATACCGTCCGAAAGGCCCTGTCTCTCCTCCAAGAGGAAG
GATTGATCAAAAAGATAAGAGGGCAAGGTTCTCAAGTCGTCAAAGAAGAAACCGTCAATTTCCCTGTATCCAACCTAACC
AGCTACCAAGAACTAGTTAAAGAACTTGGACTGCGCTCTAAAACCAACGTGGTCAGTCTGGACAAGATTATTATTGATAA
AAAATCCTCACTGATAACCGGTTTCCCAGAGTTTCGGATGGTTTGGAAGGTGGTCCGCCAGCGTGTGGTGGATGATCTGG
TATCCGTTCTGGATACGGACTATCTGGATATGGAACTCATCCCAAATCTCACTCGCCAAATTGCTGAGCAGTCTATCTAT
TCTTATATAGAAAATGGCCTCAAACTCCTTATTGATTATGCTCAGAAGGAAATCACCATTGACCACTCAAGCGACCGAGA
CAAGATTCTCATGGACATTGGCAAAGACCCTTATGTCGTTTCGATTAAATCAAAAGTCTATCTCCAAGACGGACGCCAAT
TTCAGTTTACCGAAAGTCGCCATAAGTTAGAGAAATTTAGATTTGTAGATTTTGCAAAACGCAAGAAATAA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, gntR family (GntR)

(3-66)

UTRA domain (UTRA)

(89-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2URH4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  treR Streptococcus mutans UA159

59.322

100

0.593

Multiple sequence alignment