Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   FSA28_RS05595 Genome accession   NZ_CP044495
Coordinates   1133023..1134330 (-) Length   435 a.a.
NCBI ID   WP_002264510.1    Uniprot ID   -
Organism   Streptococcus mutans strain UA140     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1128023..1139330
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FSA28_RS05565 (FSA28_0880) - 1128571..1128957 (-) 387 WP_002262221.1 cytidine deaminase -
  FSA28_RS05570 (FSA28_0881) deoC 1128947..1129609 (-) 663 WP_002288084.1 deoxyribose-phosphate aldolase -
  FSA28_RS05575 (FSA28_0882) - 1129628..1130905 (-) 1278 WP_002291163.1 pyrimidine-nucleoside phosphorylase -
  FSA28_RS05580 (FSA28_0883) - 1131014..1131610 (-) 597 WP_002283580.1 class I SAM-dependent methyltransferase -
  FSA28_RS05585 (FSA28_0884) coaA 1131706..1132626 (+) 921 WP_002262217.1 type I pantothenate kinase -
  FSA28_RS05590 (FSA28_0885) rpsT 1132680..1132934 (+) 255 WP_011074586.1 30S ribosomal protein S20 -
  FSA28_RS05595 (FSA28_0886) ciaH 1133023..1134330 (-) 1308 WP_002264510.1 three-component system sensor histidine kinase CiaH Regulator
  FSA28_RS05600 (FSA28_0887) ciaR 1134320..1134994 (-) 675 WP_088741834.1 three-component system response regulator CiaR Regulator
  FSA28_RS05605 (FSA28_0888) ciaX 1135045..1135308 (-) 264 WP_002291165.1 three-component system regulator CiaX -
  FSA28_RS05610 (FSA28_0890) - 1135710..1138259 (-) 2550 WP_002291167.1 M1 family metallopeptidase -
  FSA28_RS05615 (FSA28_0891) phoU 1138300..1138953 (-) 654 WP_002262211.1 phosphate signaling complex protein PhoU -

Sequence

Protein


Download         Length: 435 a.a.        Molecular weight: 49856.29 Da        Isoelectric Point: 9.7262

>NTDB_id=390438 FSA28_RS05595 WP_002264510.1 1133023..1134330(-) (ciaH) [Streptococcus mutans strain UA140]
MLIKLRKQKQDENISFFSHFFAVFTGIFFVMTVIIIQVMHFGIYSSVDNSLKIATENVNDYVNMTLSHNNPITEAENGDA
SFKVKSNGQMAANTDTILYDKKHNVINNVNAFSSLYHIRPKLKDIGDIVEQEAKNIYGQTEKYRTVTVKVNNDFYPQIKF
ATIVINTTQLEEANTRYVTIIISVMIVFWLISVIASVYLAKWSQKPILENYEKQKSFVENASHELRTPLAVLQNRLESLF
RKPEATILDSSESIASSLEEVRNMRMLTANLLNLARRDDGIKPEITEIQPRFFDDTFKNYEMIARENGKKLHITNKVNRQ
IKTDKTLLKQLMTILFDNAVKYTDNDGEIWLDVKTTDRSLIFSVADNGQGISDEDKKKIFDRFYRVDKARTRQKGGFGLG
LSLAKQITDSLKGSIIVKDKKPQGVMFEARLLANK

Nucleotide


Download         Length: 1308 bp        

>NTDB_id=390438 FSA28_RS05595 WP_002264510.1 1133023..1134330(-) (ciaH) [Streptococcus mutans strain UA140]
ATGCTAATTAAATTAAGAAAACAAAAGCAGGATGAGAATATTTCGTTTTTCAGTCATTTCTTTGCTGTTTTTACTGGAAT
ATTCTTTGTTATGACAGTTATTATTATTCAGGTTATGCATTTTGGTATCTATTCTTCAGTTGATAATAGTCTAAAAATAG
CAACTGAGAATGTCAATGATTATGTCAATATGACTCTATCGCATAATAATCCTATTACTGAAGCTGAAAATGGAGATGCC
TCTTTTAAAGTAAAATCAAATGGCCAGATGGCTGCTAATACAGATACTATTCTTTATGATAAAAAGCATAACGTCATCAA
TAATGTCAATGCCTTCTCTTCTTTGTATCATATTCGCCCTAAACTAAAAGATATTGGTGATATTGTTGAACAAGAAGCTA
AGAATATTTACGGTCAGACCGAAAAGTATCGGACAGTGACAGTTAAGGTAAATAATGATTTTTACCCACAGATAAAATTT
GCAACAATTGTTATTAATACAACACAGCTTGAAGAGGCTAATACGCGTTATGTTACGATTATTATCAGTGTGATGATTGT
TTTTTGGCTTATATCAGTTATTGCCAGTGTTTATTTAGCGAAGTGGAGTCAAAAACCGATTCTGGAAAATTATGAAAAGC
AAAAATCATTTGTTGAAAATGCTAGTCATGAATTACGTACTCCTTTGGCTGTTTTGCAAAATCGCTTGGAGAGTTTGTTT
CGAAAACCAGAGGCTACTATCTTAGATTCTTCGGAATCTATTGCTTCTAGTTTGGAAGAGGTCAGAAACATGAGAATGCT
GACAGCAAATCTCCTTAATTTAGCCCGTCGGGATGATGGTATCAAACCAGAAATAACAGAAATTCAACCTCGTTTTTTTG
ATGATACTTTTAAAAATTATGAGATGATCGCTCGAGAAAATGGGAAAAAATTGCATATTACCAATAAGGTCAACCGTCAA
ATTAAGACAGATAAGACTTTGCTGAAGCAATTAATGACTATTCTTTTTGATAATGCTGTCAAATATACAGATAACGACGG
GGAAATTTGGCTGGACGTCAAGACAACTGATCGCAGTTTAATTTTTTCAGTTGCGGACAATGGTCAAGGTATTTCAGACG
AGGATAAGAAGAAAATTTTTGATCGTTTTTATCGCGTCGATAAAGCCAGAACACGACAAAAGGGTGGGTTCGGACTTGGT
TTGTCTTTGGCAAAACAAATAACAGACAGCTTAAAAGGCAGCATTATTGTTAAAGATAAAAAACCACAAGGAGTAATGTT
TGAAGCTCGCCTGCTTGCTAATAAATAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(215-280)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(324-431)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

99.77

100

0.998
  ciaH Streptococcus pneumoniae Rx1

55.632

100

0.556
  ciaH Streptococcus pneumoniae D39

55.632

100

0.556
  ciaH Streptococcus pneumoniae R6

55.632

100

0.556
  ciaH Streptococcus pneumoniae TIGR4

55.632

100

0.556

Multiple sequence alignment