Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD/blpH   Type   Regulator
Locus tag   FSA40_RS08880 Genome accession   NZ_CP044493
Coordinates   1749971..1751296 (-) Length   441 a.a.
NCBI ID   WP_002292008.1    Uniprot ID   -
Organism   Streptococcus mutans strain MD     
Function   phosphorylation of ComE; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1744971..1756296
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FSA40_RS08835 (FSA40_1770) - 1745370..1745534 (-) 165 WP_002265308.1 hypothetical protein -
  FSA40_RS10485 - 1745974..1746186 (+) 213 Protein_1649 IS3 family transposase -
  FSA40_RS08850 (FSA40_1772) - 1746309..1746713 (-) 405 WP_002263912.1 hypothetical protein -
  FSA40_RS08855 (FSA40_1773) - 1746860..1747279 (-) 420 WP_151416432.1 hypothetical protein -
  FSA40_RS08865 (FSA40_1775) - 1748660..1749061 (-) 402 WP_002310604.1 hypothetical protein -
  FSA40_RS08870 (FSA40_1776) cipB 1749192..1749422 (-) 231 WP_002265368.1 Blp family class II bacteriocin Regulator
  FSA40_RS08875 (FSA40_1777) comC/blpC 1749689..1749829 (+) 141 WP_002270250.1 ComC/BlpC family leader-containing pheromone/bacteriocin Regulator
  FSA40_RS08880 (FSA40_1778) comD/blpH 1749971..1751296 (-) 1326 WP_002292008.1 GHKL domain-containing protein Regulator
  FSA40_RS08885 (FSA40_1779) comE/blpR 1751293..1752045 (-) 753 WP_151416433.1 response regulator transcription factor Regulator
  FSA40_RS08890 (FSA40_1780) - 1752517..1753155 (-) 639 WP_002265117.1 VTT domain-containing protein -
  FSA40_RS08895 (FSA40_1781) - 1753202..1753828 (-) 627 WP_002265453.1 hypothetical protein -
  FSA40_RS08900 (FSA40_1782) der 1753903..1755213 (-) 1311 WP_063330949.1 ribosome biogenesis GTPase Der -
  FSA40_RS08905 (FSA40_1783) dnaI 1755226..1756125 (-) 900 WP_002265120.1 primosomal protein DnaI -

Sequence

Protein


Download         Length: 441 a.a.        Molecular weight: 50441.61 Da        Isoelectric Point: 9.8776

>NTDB_id=390390 FSA40_RS08880 WP_002292008.1 1749971..1751296(-) (comD/blpH) [Streptococcus mutans strain MD]
MNEALMILSNGLLTYLTVLFLLFLFSKVSNVTLSKKELTLFSISNFLIMIAVTMVNVNLFYPAEPLYFIALSIYLNRQNS
LSLNIFYGLLPVASSDLFRRAIIFFILDGTQGIVMGSSIITTYMIEFAGIALSYLFLSVFNVDIGRLKDSLTKMKVKKRL
IPMNITMLLYYLLIQVLYVIESYNVIPTLKFRKFVVIVYLILFLILISFLSQYTKQKVQNEIMAQKEAQIRNITQYSQQI
ESLYKDIRSFRHDYLNILTSLRLGIENKDLASIEKIYHQILEKTGHQLQDTRYNIGHLANIQNDAVKGILSAKILEAQNK
KIAVNVEVSSKIQLPGMELLDFITILSILCDNAIEAAFESLNPEIQLAFFKKNGSIVFIIQNSTKEKQIDVSKIFKENYS
TKGSNRGIGLAKVNHILEHYPKTSLQTSSHHHLFKQLLIIK

Nucleotide


Download         Length: 1326 bp        

>NTDB_id=390390 FSA40_RS08880 WP_002292008.1 1749971..1751296(-) (comD/blpH) [Streptococcus mutans strain MD]
ATGAATGAAGCCTTAATGATACTTTCAAATGGTTTATTAACTTATCTAACCGTTCTATTTCTCTTGTTTCTATTTTCTAA
GGTAAGTAATGTCACTTTATCGAAAAAGGAATTAACTCTTTTTTCGATAAGCAATTTTCTGATAATGATTGCTGTTACGA
TGGTGAACGTAAACCTGTTTTATCCTGCAGAGCCTCTTTATTTTATAGCTTTATCAATTTATCTTAATAGACAGAATAGT
CTTTCTCTAAATATATTTTATGGTCTGCTGCCTGTTGCCAGTTCTGACTTGTTTAGGCGGGCAATCATATTCTTTATCTT
GGATGGAACTCAAGGAATTGTAATGGGCAGTAGCATTATAACCACCTATATGATCGAGTTTGCAGGAATAGCGCTAAGTT
ACCTCTTTCTCAGTGTGTTCAATGTTGATATTGGTCGACTTAAAGATAGTTTGACCAAGATGAAGGTCAAAAAACGCTTG
ATTCCAATGAATATTACTATGCTTCTATACTACCTTTTAATACAGGTATTGTATGTTATAGAGAGTTATAATGTGATACC
GACTTTAAAATTTCGTAAATTTGTCGTTATTGTCTATCTTATTTTATTTTTGATTCTGATCTCATTTTTAAGCCAATATA
CCAAACAAAAGGTTCAAAATGAGATAATGGCACAAAAGGAAGCTCAGATTCGAAATATCACCCAGTATAGTCAGCAAATA
GAATCTCTTTACAAGGATATTCGAAGTTTCCGCCATGATTATCTGAATATTTTAACTAGCCTCAGATTAGGCATTGAAAA
TAAAGATTTAGCTAGTATTGAAAAGATTTACCATCAAATCTTAGAAAAAACAGGACATCAATTGCAGGATACCCGTTATA
ATATCGGCCATCTAGCTAATATTCAAAACGATGCTGTCAAGGGTATCTTGTCAGCAAAAATCTTAGAAGCTCAGAATAAA
AAGATTGCTGTCAATGTAGAAGTCTCAAGTAAAATACAACTGCCTGGGATGGAGTTGCTTGATTTCATTACTATACTTTC
TATCTTGTGTGATAATGCCATTGAGGCTGCTTTCGAATCATTAAATCCTGAAATTCAGTTAGCCTTTTTTAAGAAAAATG
GCAGCATAGTCTTTATCATTCAGAATTCCACCAAAGAAAAACAAATAGATGTGAGTAAAATTTTTAAAGAAAACTATTCC
ACTAAAGGCTCCAATCGCGGTATTGGTTTAGCAAAGGTGAATCATATTCTTGAACATTATCCCAAAACCAGTTTACAAAC
AAGCAGTCATCATCATTTATTCAAGCAACTCCTAATAATAAAATAG

Domains

Predicted by InterproScan.

GHKL domain (HATPase_c_5)

(337-440)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD/blpH Streptococcus mutans UA159

99.546

100

0.995

Multiple sequence alignment