Detailed information    

insolico Bioinformatically predicted

Overview

Name   disA   Type   Machinery gene
Locus tag   HJD23_RS17330 Genome accession   NZ_CP053109
Coordinates   3877653..3878777 (+) Length   374 a.a.
NCBI ID   WP_141314654.1    Uniprot ID   A0A4Y3VSV7
Organism   Streptomyces sp. Z423-1     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 3872653..3883777
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HJD23_RS17315 - 3873268..3874149 (+) 882 WP_171109106.1 hypothetical protein -
  HJD23_RS17320 - 3874203..3875939 (-) 1737 WP_171109108.1 hypothetical protein -
  HJD23_RS17325 radA 3876163..3877572 (+) 1410 WP_171109110.1 DNA repair protein RadA Machinery gene
  HJD23_RS17330 disA 3877653..3878777 (+) 1125 WP_141314654.1 DNA integrity scanning diadenylate cyclase DisA Machinery gene
  HJD23_RS17335 - 3878893..3879744 (-) 852 WP_171109112.1 hypothetical protein -
  HJD23_RS17340 - 3879983..3880930 (+) 948 WP_171109114.1 A/G-specific adenine glycosylase -
  HJD23_RS17345 - 3881184..3881732 (+) 549 WP_171109116.1 SigE family RNA polymerase sigma factor -
  HJD23_RS17350 - 3881720..3882412 (+) 693 WP_171109118.1 hypothetical protein -
  HJD23_RS17355 cseB 3882461..3883165 (+) 705 WP_171109120.1 two-component system response regulator CseB -

Sequence

Protein


Download         Length: 374 a.a.        Molecular weight: 39962.69 Da        Isoelectric Point: 4.9201

>NTDB_id=390137 HJD23_RS17330 WP_141314654.1 3877653..3878777(+) (disA) [Streptomyces sp. Z423-1]
MAANDRAAAPGKSGGSAGSDGLMRASLSAVAPGTPLRDGLERVLRGNTGGLIVLGSDKTVEAMCTGGFVLDVEFTATRLR
ELCKLDGGIVLSSDLSKILRAGVQLVPDPTIPTEETGTRHRTADRVSKQVGFPVVSVSQSMRLIALYVDGQRRVLEDSAA
ILSRANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVSAVAQRLEMVRRIATEIAEYVVELGTDGRLLALQLDELIA
GVEPERELVVRDYVPEPTAKRSRTVDEALAELDALSHAELLELPTVARALGYTGSPEALDSAVSPRGFRLLAKVPRLPGA
IIDRLVEHFGGLQKLLAASVDDLQTVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide


Download         Length: 1125 bp        

>NTDB_id=390137 HJD23_RS17330 WP_141314654.1 3877653..3878777(+) (disA) [Streptomyces sp. Z423-1]
GTGGCAGCCAACGACCGGGCAGCAGCTCCCGGAAAGTCCGGTGGGAGTGCCGGTTCCGATGGCCTGATGCGCGCCTCGCT
GAGCGCCGTGGCACCCGGCACGCCCCTGCGTGACGGCCTTGAGCGGGTCCTGCGCGGCAACACCGGCGGCCTGATCGTGC
TCGGCTCCGACAAGACCGTCGAAGCCATGTGCACGGGTGGTTTCGTGCTGGATGTCGAGTTCACGGCGACCCGGCTGCGC
GAGCTGTGCAAGCTCGACGGCGGCATCGTGCTCTCCTCCGACCTGTCGAAGATCCTCCGGGCGGGCGTCCAGCTGGTCCC
CGACCCCACGATCCCGACCGAGGAGACCGGCACCCGGCACCGCACCGCGGACCGCGTGAGCAAGCAGGTCGGCTTCCCGG
TGGTCTCGGTCTCCCAGTCCATGCGGCTGATCGCCCTCTACGTCGACGGCCAGCGCCGCGTCCTGGAGGACTCCGCGGCG
ATCCTGTCCCGCGCCAACCAGGCCCTCGCGACCCTGGAGCGCTACAAGCTCCGCCTCGACGAGGTCGCGGGCACGCTGTC
CGCGCTGGAGATCGAGGACCTGGTGACGGTCCGGGACGTCTCGGCGGTGGCGCAGCGGCTGGAGATGGTGCGCCGGATCG
CGACCGAAATCGCCGAGTACGTGGTCGAGCTGGGCACCGACGGGCGGCTGCTCGCGCTCCAGCTGGACGAGTTGATCGCG
GGCGTGGAGCCCGAGCGCGAGCTGGTCGTCCGGGACTACGTCCCCGAGCCCACGGCCAAGCGCTCACGCACGGTGGACGA
GGCACTGGCCGAGCTGGACGCCCTCAGCCACGCCGAGCTGCTCGAACTGCCCACGGTGGCCCGGGCGCTGGGCTACACCG
GCTCCCCCGAGGCCCTCGACTCCGCGGTCTCACCGCGCGGCTTCCGGCTGCTGGCCAAGGTGCCGCGCCTGCCGGGCGCC
ATCATCGACCGGCTGGTGGAACACTTCGGCGGCCTGCAGAAGCTGCTCGCCGCGAGCGTCGACGACCTCCAGACGGTGGA
CGGCGTGGGCGAGGCCCGGGCACGCAGCGTACGGGAGGGCCTGTCGCGGTTGGCGGAGTCGTCGATCCTGGAGCGCTACG
TCTAG

Domains

Predicted by InterProScan.

Helix-hairpin-helix motif (HHH_2)

(324-359)

DisA bacterial checkpoint controller nucleotide-binding (DAC)

(38-151)

DisA bacterial checkpoint controller linker region (DisA-linker)

(155-297)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A4Y3VSV7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  disA Bacillus subtilis subsp. subtilis str. 168

47.399

92.513

0.439

Multiple sequence alignment