Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD/blpH   Type   Regulator
Locus tag   F5989_RS07760 Genome accession   NZ_CP044221
Coordinates   1560462..1561787 (+) Length   441 a.a.
NCBI ID   WP_002289696.1    Uniprot ID   -
Organism   Streptococcus mutans strain NCH105     
Function   phosphorylation of ComE; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1555462..1566787
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  F5989_RS07735 (F5989_07875) dnaI 1555632..1556531 (+) 900 WP_002267936.1 primosomal protein DnaI -
  F5989_RS07740 (F5989_07880) der 1556544..1557854 (+) 1311 WP_002266899.1 ribosome biogenesis GTPase Der -
  F5989_RS07745 (F5989_07885) - 1557929..1558555 (+) 627 WP_002266898.1 hypothetical protein -
  F5989_RS07750 (F5989_07890) - 1558603..1559241 (+) 639 WP_002262115.1 VTT domain-containing protein -
  F5989_RS07755 (F5989_07895) comE/blpR 1559713..1560465 (+) 753 WP_002262114.1 response regulator transcription factor Regulator
  F5989_RS07760 (F5989_07900) comD/blpH 1560462..1561787 (+) 1326 WP_002289696.1 sensor histidine kinase Regulator
  F5989_RS07765 (F5989_07905) comC/blpC 1561929..1562069 (-) 141 WP_002267610.1 ComC/BlpC family leader-containing pheromone/bacteriocin Regulator
  F5989_RS07770 (F5989_07910) cipB 1562336..1562566 (+) 231 WP_002265368.1 Blp family class II bacteriocin Regulator
  F5989_RS07775 (F5989_07915) - 1562697..1563098 (+) 402 WP_002310604.1 hypothetical protein -
  F5989_RS07785 (F5989_07925) - 1564479..1564898 (+) 420 WP_002263913.1 hypothetical protein -
  F5989_RS07790 (F5989_07930) - 1565045..1565449 (+) 405 WP_002263912.1 hypothetical protein -
  F5989_RS10295 - 1565572..1565784 (-) 213 Protein_1468 IS3 family transposase -
  F5989_RS07795 (F5989_07945) - 1566224..1566388 (+) 165 WP_002265308.1 hypothetical protein -

Sequence

Protein


Download         Length: 441 a.a.        Molecular weight: 50574.71 Da        Isoelectric Point: 9.8211

>NTDB_id=388865 F5989_RS07760 WP_002289696.1 1560462..1561787(+) (comD/blpH) [Streptococcus mutans strain NCH105]
MNEALMILSNGLLTYLTVLFLLFLFSKVSNVTLSKKELTLFSISNFLIMIAVTMVNVNLFYPAEPLYFIALSIYLNRQNS
LSLNIFYGLLPVASSDLFRRAIIFFILDGTQGIVMGSSIITTYMIEFAGIALSYLFLSVFNVDIGRLKDSLTKMKVKKRL
IPMNITMLLYYLLIQVLYVIESYNVIPTLKFRKFVVIVYLILFLILFSFLSQYTKQKVQNEIMAQKEAQIRNITQYSQQI
ESLYKDIRSFRHDYLNILTSLRLGIENKDLASIEKIYHQILEKTGHQLQDTRYNIGHLANIQNDAVKGILSAKILEAQNK
KIAVNVEVSSKIQLPEMELLDFITILSILCDNAIEAAFESLNPEIQLAFFKKNGSIVFIIQNSTKEKQIDVSKIFKENYS
TKGSNRGIGLAKVNHILEHYPKTSLQTSNHHHLFKQLLIIK

Nucleotide


Download         Length: 1326 bp        

>NTDB_id=388865 F5989_RS07760 WP_002289696.1 1560462..1561787(+) (comD/blpH) [Streptococcus mutans strain NCH105]
ATGAATGAAGCCTTAATGATACTTTCAAATGGTTTATTAACTTATCTAACCGTTCTATTTCTCTTGTTTCTATTTTCTAA
GGTAAGTAATGTCACTTTATCGAAAAAGGAATTAACTCTTTTTTCGATAAGCAATTTTCTGATAATGATTGCTGTTACGA
TGGTGAACGTAAACCTGTTTTATCCTGCAGAGCCTCTTTATTTTATAGCTTTATCAATTTATCTTAATAGACAGAATAGT
CTTTCTCTAAATATATTTTATGGTCTGCTGCCTGTTGCCAGTTCTGACTTGTTTAGGCGGGCAATCATATTCTTTATCTT
GGATGGAACTCAAGGAATTGTAATGGGCAGTAGCATTATAACCACCTATATGATCGAGTTTGCAGGAATAGCGCTAAGTT
ACCTCTTTCTCAGTGTGTTCAATGTTGATATTGGTCGACTTAAAGATAGTTTGACCAAGATGAAGGTCAAAAAACGCTTG
ATTCCAATGAATATTACTATGCTTCTATACTACCTTTTAATACAGGTATTGTATGTTATAGAGAGTTATAATGTGATACC
GACTTTAAAATTTCGTAAATTTGTCGTTATTGTCTATCTTATTTTATTTTTGATTCTGTTCTCATTTTTAAGCCAATATA
CCAAACAAAAGGTTCAAAATGAGATAATGGCACAAAAGGAAGCTCAGATTCGAAATATCACCCAGTATAGTCAGCAAATA
GAATCTCTTTACAAGGATATTCGAAGTTTCCGCCATGATTATCTGAATATTTTAACTAGCCTCAGATTAGGCATTGAAAA
TAAAGATTTAGCTAGTATTGAAAAGATTTACCATCAAATCTTAGAAAAAACAGGACATCAATTGCAGGATACCCGTTATA
ATATCGGCCATCTAGCTAATATTCAAAACGATGCTGTCAAGGGTATCTTGTCAGCAAAAATCTTAGAAGCTCAGAATAAA
AAGATTGCTGTCAATGTAGAAGTCTCAAGTAAAATACAACTGCCTGAGATGGAGTTGCTTGATTTCATTACCATACTTTC
TATCTTGTGTGATAATGCCATTGAGGCTGCTTTCGAATCATTAAATCCTGAAATTCAGTTAGCCTTTTTTAAGAAAAATG
GCAGTATAGTCTTTATCATTCAGAATTCCACCAAAGAAAAACAAATAGATGTGAGTAAAATTTTTAAAGAAAACTATTCC
ACTAAAGGCTCCAATCGCGGTATTGGTTTAGCAAAGGTGAATCATATTCTTGAACATTATCCCAAAACCAGTTTACAAAC
AAGCAATCATCATCATTTATTCAAGCAACTCCTAATAATAAAATAG

Domains

Predicted by InterproScan.

GHKL domain (HATPase_c_5)

(337-440)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD/blpH Streptococcus mutans UA159

99.773

100

0.998

Multiple sequence alignment