Detailed information NTG0038855

Bioinformatically predicted

Overview

• Name: ruvA
• Type: Machinery gene
• Locus tag: NMBM01240149_RS10280
• Genome accession: NC_017514
• Coordinates: 1998852..1999436 (+)
• Length: 194 a.a.
• NCBI ID: WP_002223336.1
• Uniprot ID: Q9K1A2
• Organism: Neisseria meningitidis M01-240149
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 1993852..2004436

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NMBM01240149_RS10245 (NMBM01240149_1815)	-	1994290..1994559 (-)	270	WP_002218669.1	hypothetical protein	-
NMBM01240149_RS10250 (NMBM01240149_1816)	-	1994747..1995535 (-)	789	WP_002218668.1	hypothetical protein	-
NMBM01240149_RS10255 (NMBM01240149_1817)	bioH	1995537..1996280 (-)	744	WP_002218667.1	pimeloyl-ACP methyl ester esterase BioH	-
NMBM01240149_RS10260 (NMBM01240149_1818)	-	1996279..1997004 (+)	726	WP_002218666.1	ComF family protein	-
NMBM01240149_RS10265 (NMBM01240149_1819)	trmL	1997069..1997533 (+)	465	WP_002218664.1	tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL	-
NMBM01240149_RS13440	-	1997544..1997666 (+)	123	WP_009346050.1	hypothetical protein	-
NMBM01240149_RS10270 (NMBM01240149_1820)	-	1997663..1998382 (+)	720	WP_002223338.1	septal ring lytic transglycosylase RlpA family protein	-
NMBM01240149_RS10275 (NMBM01240149_1821)	-	1998444..1998770 (+)	327	WP_002221923.1	PepSY domain-containing protein	-
NMBM01240149_RS10280 (NMBM01240149_1822)	ruvA	1998852..1999436 (+)	585	WP_002223336.1	Holliday junction branch migration protein RuvA	Machinery gene
NMBM01240149_RS15215	-	1999436..1999573 (+)	138	WP_002231623.1	hypothetical protein	-
NMBM01240149_RS10290 (NMBM01240149_1823)	-	1999599..2001455 (+)	1857	WP_002223335.1	ABC transporter ATP-binding protein	-
NMBM01240149_RS10295 (NMBM01240149_1824)	rsgA	2001460..2002383 (+)	924	WP_002223334.1	ribosome small subunit-dependent GTPase A	-
NMBM01240149_RS10300 (NMBM01240149_1825)	-	2002644..2002868 (+)	225	WP_002258037.1	exodeoxyribonuclease VII small subunit	-
NMBM01240149_RS10305 (NMBM01240149_1826)	-	2002852..2003748 (+)	897	WP_002218656.1	polyprenyl synthetase family protein	-
NMBM01240149_RS10310 (NMBM01240149_1827)	-	2003857..2004156 (-)	300	WP_002223333.1	DUF2818 family protein	-

Sequence

Protein

• Length: 194 a.a.
• Molecular weight: 20687.90 Da
• Isoelectric Point: 5.3813

>NTDB_id=38855 NMBM01240149_RS10280 WP_002223336.1 1998852..1999436(+) (ruvA) [Neisseria meningitidis M01-240149]
MISRLTGKLVEKNPPQIVIDVNGVGYEADVSMQTFYNLPPVGESVQLFTQLIIREDAHLLFGFATAEERKTFRQLIKVGG
IGAKTALGILSAMTADELARAVAEEDVKRLSSAPGIGKKTAERMVLELRGKLVAHTVTDGLFAAAPAADETEDIVSTLLA
LGYSEREAKAAVKGVPEGTDVGEGVRLALKNLLK

Nucleotide

• Length: 585 bp

>NTDB_id=38855 NMBM01240149_RS10280 WP_002223336.1 1998852..1999436(+) (ruvA) [Neisseria meningitidis M01-240149]
ATGATCAGCAGACTGACCGGCAAACTGGTTGAAAAAAACCCTCCGCAAATCGTCATCGATGTCAACGGTGTCGGCTATGA
GGCCGACGTATCGATGCAGACCTTCTACAACCTGCCGCCCGTGGGTGAAAGCGTACAACTGTTTACCCAGCTTATCATTC
GGGAAGACGCACATCTTTTATTTGGTTTTGCCACTGCGGAAGAACGCAAGACCTTCCGCCAACTGATTAAGGTCGGCGGC
ATCGGCGCGAAAACGGCTTTGGGCATTTTGTCAGCGATGACGGCAGACGAGCTGGCGCGGGCGGTTGCCGAAGAAGATGT
CAAACGCCTGTCTTCCGCGCCGGGAATCGGCAAAAAAACCGCCGAACGTATGGTCTTGGAACTGCGCGGCAAGCTGGTCG
CGCATACGGTAACGGACGGGCTGTTTGCCGCCGCACCCGCCGCCGACGAAACGGAAGACATCGTCAGCACGCTGCTTGCG
CTGGGTTACAGCGAACGCGAAGCAAAAGCGGCGGTCAAAGGCGTTCCGGAGGGGACGGACGTGGGCGAAGGCGTGCGCCT
TGCTTTGAAAAACCTGCTGAAATAA

Domains

Predicted by InterProScan.

• RuvA N terminal domain (RuvA_N) (1-62)

• Helix-hairpin-helix domain (HHH_5) (72-129)

• RuvA, C-terminal domain (RuvA_C) (150-192)

3D structure

• AlphaFold DB: Q9K1A2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ruvA	Streptococcus pneumoniae R6	37.5	100	0.387
ruvA	Streptococcus pneumoniae D39	37.5	100	0.387
ruvA	Streptococcus pneumoniae TIGR4	37	100	0.381
ruvA	Bacillus subtilis subsp. subtilis str. 168	35.437	100	0.376