Detailed information NTG0038796

Bioinformatically predicted

Overview

• Name: pilU
• Type: Machinery gene
• Locus tag: NMBM01240149_RS00240
• Genome accession: NC_017514
• Coordinates: 50022..51248 (-)
• Length: 408 a.a.
• NCBI ID: WP_002240931.1
• Uniprot ID: -
• Organism: Neisseria meningitidis M01-240149
• Function: mediate the depolymerization of the type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 45022..56248

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NMBM01240149_RS00235 (NMBM01240149_0044)	yccS	47586..49736 (-)	2151	WP_002240930.1	YccS family putative transporter	-
NMBM01240149_RS00240 (NMBM01240149_0045)	pilU	50022..51248 (-)	1227	WP_002240931.1	PilT/PilU family type 4a pilus ATPase	Machinery gene
NMBM01240149_RS00245 (NMBM01240149_0046)	pilT	51411..52454 (-)	1044	WP_002240932.1	type IV pilus twitching motility protein PilT	Machinery gene
NMBM01240149_RS00250 (NMBM01240149_0047)	-	52574..53260 (+)	687	WP_002240933.1	YggS family pyridoxal phosphate-dependent enzyme	-
NMBM01240149_RS00255 (NMBM01240149_0048)	-	53260..53670 (+)	411	WP_002240934.1	hypothetical protein	-
NMBM01240149_RS00260 (NMBM01240149_0049)	proC	53701..54510 (+)	810	WP_226879339.1	pyrroline-5-carboxylate reductase	-
NMBM01240149_RS00265 (NMBM01240149_0050)	dksA	54657..55073 (+)	417	WP_002215267.1	RNA polymerase-binding protein DksA	-

Sequence

Protein

• Length: 408 a.a.
• Molecular weight: 45644.25 Da
• Isoelectric Point: 6.9640

>NTDB_id=38796 NMBM01240149_RS00240 WP_002240931.1 50022..51248(-) (pilU) [Neisseria meningitidis M01-240149]
MNTDNLHDILDEMVQVYSQKKQSRSETPAEIGAHFHPLLDRLCETAEAQNASDILISKGFPPSLKINSALTPQPQKALTG
EETAAIAASTMNAEQSEIFRRDGEINYSVQSRSGTRYRANAYHSQGSAGLVLRRINHVIPQMQELGLPEKLKDLAVAPRG
LLIIVGPTGSGKSTTMATMLEHRNKTLPGHIVTIEDPIEFIYKPRRCIFTQREIGVDTINWQTAVQNAMRQSPDVVCIGE
VRSRESMEYAMQLAQTGHLCIFTLHANTAPQSLERILNFYPKEQHNQILIDIALNLTGIICQRLALKQDKTGRTAVVDLL
INTPAIQDFILKGDLMNISKIMETAKTDGMQTMDQNLFELYRHGIISYEEALRQSVSANNLRLHIQLHKEGKTPELLYDR
VNGLNLIS

Nucleotide

• Length: 1227 bp

>NTDB_id=38796 NMBM01240149_RS00240 WP_002240931.1 50022..51248(-) (pilU) [Neisseria meningitidis M01-240149]
ATGAATACCGATAACCTGCACGACATCTTGGACGAAATGGTTCAAGTGTATTCTCAAAAAAAACAAAGCCGATCCGAAAC
CCCGGCCGAAATCGGCGCACACTTCCACCCGCTGCTCGACCGCCTGTGCGAAACCGCAGAAGCACAAAACGCGTCCGACA
TCCTTATCAGCAAAGGATTCCCGCCCTCGTTGAAAATCAACAGCGCATTAACCCCGCAGCCGCAAAAGGCGCTGACGGGC
GAGGAAACCGCCGCCATCGCCGCATCGACGATGAACGCCGAACAATCGGAAATATTCCGGCGCGACGGCGAAATCAACTA
TTCCGTCCAGTCGCGCAGCGGCACGCGCTACCGCGCCAACGCCTACCACAGCCAAGGCAGCGCAGGTTTGGTTTTGCGGC
GCATCAACCACGTCATCCCGCAAATGCAGGAATTGGGCCTGCCCGAAAAACTCAAAGACCTCGCCGTCGCGCCGCGCGGG
CTGCTGATTATCGTCGGACCTACCGGTTCGGGCAAATCCACCACGATGGCGACTATGCTCGAACACCGCAACAAAACTCT
GCCCGGCCATATCGTTACCATCGAAGACCCGATAGAGTTTATCTACAAGCCGCGCCGCTGCATCTTTACCCAGCGCGAAA
TCGGCGTCGACACCATAAACTGGCAGACGGCGGTACAAAACGCTATGCGCCAGTCCCCCGACGTGGTCTGCATCGGCGAA
GTCCGCAGCAGGGAAAGTATGGAATACGCGATGCAGCTCGCCCAAACCGGCCACCTGTGCATTTTTACGCTCCACGCCAA
CACCGCGCCGCAGTCGCTCGAACGCATACTCAACTTCTACCCCAAAGAACAGCACAACCAAATACTGATCGACATCGCCC
TCAACCTGACCGGCATCATCTGCCAACGCCTCGCCCTCAAACAAGACAAAACGGGCAGGACGGCGGTTGTCGACTTGCTC
ATCAACACGCCCGCCATCCAAGACTTCATCCTGAAGGGCGACCTGATGAACATCAGTAAAATCATGGAAACCGCCAAAAC
CGACGGAATGCAGACGATGGATCAAAACCTTTTCGAACTGTACCGTCACGGCATCATCAGTTACGAAGAAGCCCTGCGCC
AGTCCGTTTCCGCCAACAACCTGCGATTGCACATCCAACTGCACAAAGAAGGCAAAACGCCCGAACTCCTTTACGACAGG
GTCAACGGTCTCAACCTCATTTCCTGA

Domains

Predicted by InterProScan.

• Type II/IV secretion system protein (T2SSE) (49-305)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilU	Acinetobacter baylyi ADP1	44.875	88.48	0.397
pilU	Pseudomonas stutzeri DSM 10701	44.944	87.255	0.392
pilU	Vibrio cholerae strain A1552	46.726	82.353	0.385