Detailed information NTG0387728

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: FOB76_RS02055
• Genome accession: NZ_CP044093
• Coordinates: 388371..389372 (-)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A4U7H1B9
• Organism: Streptococcus pyogenes strain FDAARGOS_668
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 383371..394372

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FOB76_RS02040 (FOB76_02040)	thrS	383541..385484 (-)	1944	WP_002985672.1	threonine--tRNA ligase	-
FOB76_RS02045 (FOB76_02045)	-	385906..387240 (-)	1335	WP_002990700.1	glycosyltransferase family 4 protein	-
FOB76_RS02050 (FOB76_02050)	-	387242..388240 (-)	999	WP_002990703.1	glycosyltransferase family 4 protein	-
FOB76_RS02055 (FOB76_02055)	ccpA	388371..389372 (-)	1002	WP_002985680.1	catabolite control protein A	Regulator
FOB76_RS02060 (FOB76_02060)	-	389546..390631 (+)	1086	WP_002990707.1	aminopeptidase P family protein	-
FOB76_RS02065 (FOB76_02065)	-	390680..391345 (+)	666	WP_002985684.1	NAD(P)H-dependent oxidoreductase	-
FOB76_RS02070 (FOB76_02070)	-	391356..391733 (+)	378	WP_002985686.1	VOC family protein	-
FOB76_RS02075 (FOB76_02075)	-	391878..392804 (+)	927	WP_002990711.1	glycosyltransferase family 2 protein	-
FOB76_RS02080 (FOB76_02080)	-	393015..393698 (+)	684	WP_002990714.1	DUF969 domain-containing protein	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=387728 FOB76_RS02055 WP_002985680.1 388371..389372(-) (ccpA) [Streptococcus pyogenes strain FDAARGOS_668]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=387728 FOB76_RS02055 WP_002985680.1 388371..389372(-) (ccpA) [Streptococcus pyogenes strain FDAARGOS_668]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
CAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAATTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAACGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGGTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGTCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCAGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACCAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4U7H1B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559