Detailed information NTG0038712

Bioinformatically predicted

Overview

• Name: ruvA
• Type: Machinery gene
• Locus tag: NMAA_RS10390
• Genome accession: NC_017512
• Coordinates: 1981777..1982361 (+)
• Length: 194 a.a.
• NCBI ID: WP_002240238.1
• Uniprot ID: Q9JSM5
• Organism: Neisseria meningitidis WUE 2594
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 1976777..1987361

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NMAA_RS15480 (NMAA_1707)	-	1976980..1977606 (-)	627	WP_010981296.1	hypothetical protein	-
NMAA_RS15485 (NMAA_1708)	-	1977682..1978470 (-)	789	WP_002245837.1	class I SAM-dependent methyltransferase	-
NMAA_RS10365 (NMAA_1709)	bioH	1978475..1979215 (-)	741	Protein_1944	pimeloyl-ACP methyl ester esterase BioH	-
NMAA_RS10370 (NMAA_1710)	-	1979214..1979939 (+)	726	WP_002228923.1	ComF family protein	-
NMAA_RS10375 (NMAA_1711)	trmL	1980004..1980468 (+)	465	WP_002215661.1	tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL	-
NMAA_RS10380 (NMAA_1712)	-	1980596..1981315 (+)	720	WP_002245836.1	septal ring lytic transglycosylase RlpA family protein	-
NMAA_RS10385 (NMAA_1713)	-	1981369..1981695 (+)	327	WP_002218661.1	PepSY domain-containing protein	-
NMAA_RS10390 (NMAA_1714)	ruvA	1981777..1982361 (+)	585	WP_002240238.1	Holliday junction branch migration protein RuvA	Machinery gene
NMAA_RS15095	-	1982361..1982498 (+)	138	WP_002240237.1	hypothetical protein	-
NMAA_RS10400 (NMAA_1715)	-	1982524..1984380 (+)	1857	WP_002245835.1	ABC transporter ATP-binding protein	-
NMAA_RS10405 (NMAA_1716)	rsgA	1984385..1985308 (+)	924	WP_002226945.1	ribosome small subunit-dependent GTPase A	-
NMAA_RS15870	-	1985335..1985511 (+)	177	WP_079267043.1	exodeoxyribonuclease VII	-
NMAA_RS10410 (NMAA_1717)	-	1985572..1985796 (+)	225	WP_002236646.1	exodeoxyribonuclease VII small subunit	-
NMAA_RS10415 (NMAA_1718)	-	1985780..1986676 (+)	897	WP_002245834.1	polyprenyl synthetase family protein	-
NMAA_RS10420 (NMAA_1719)	-	1986785..1987084 (-)	300	WP_002226942.1	DUF2818 family protein	-

Sequence

Protein

• Length: 194 a.a.
• Molecular weight: 20599.80 Da
• Isoelectric Point: 5.1063

>NTDB_id=38712 NMAA_RS10390 WP_002240238.1 1981777..1982361(+) (ruvA) [Neisseria meningitidis WUE 2594]
MISRLTGKLVEKNPPQIVIDVNGVGYEADVSMQTFYNLPPVGESVQLFTQLIIREDAHLLFGFATAEERKTFRQLIKVGG
IGAKTALGILSAMTADELAQAVAEEDVKRLSSAPGIGKKTAERMVLELRGKLVAHAVTDGLFAAAPAADETEDIVGTLLA
LGYSEREAKAAVKGVPEGTDVGEGVRLALKNLLK

Nucleotide

• Length: 585 bp

>NTDB_id=38712 NMAA_RS10390 WP_002240238.1 1981777..1982361(+) (ruvA) [Neisseria meningitidis WUE 2594]
ATGATCAGCAGACTGACCGGCAAACTGGTTGAAAAAAACCCTCCGCAAATCGTCATCGATGTCAACGGTGTCGGCTATGA
GGCCGACGTATCGATGCAGACCTTCTACAACCTGCCGCCCGTGGGTGAAAGCGTACAACTGTTTACCCAGCTTATCATTC
GGGAAGACGCACATCTTTTATTTGGTTTTGCCACTGCGGAAGAACGCAAAACATTCCGCCAACTGATCAAGGTCGGCGGC
ATCGGCGCGAAAACGGCTTTGGGCATTTTGTCGGCGATGACGGCAGACGAGCTGGCGCAGGCGGTTGCAGAAGAAGATGT
CAAACGCCTCTCCTCCGCCCCGGGAATCGGCAAAAAAACCGCCGAACGCATGGTTTTGGAACTGCGCGGCAAGCTGGTCG
CGCATGCGGTAACGGACGGGCTGTTTGCCGCCGCACCCGCCGCCGACGAAACGGAAGACATCGTCGGCACGCTGCTTGCG
CTGGGTTACAGCGAACGCGAAGCAAAAGCGGCGGTCAAAGGCGTTCCGGAGGGGACGGACGTGGGCGAAGGCGTGCGCCT
TGCTTTGAAAAACCTGCTGAAATAA

Domains

Predicted by InterProScan.

• Helix-hairpin-helix domain (HHH_5) (72-129)

• RuvA N terminal domain (RuvA_N) (1-62)

• RuvA, C-terminal domain (RuvA_C) (150-192)

3D structure

• AlphaFold DB: Q9JSM5

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ruvA	Streptococcus pneumoniae R6	38	100	0.392
ruvA	Streptococcus pneumoniae D39	38	100	0.392
ruvA	Streptococcus pneumoniae TIGR4	37.5	100	0.387
ruvA	Bacillus subtilis subsp. subtilis str. 168	35.922	100	0.381