Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   HHJ36_RS09780 Genome accession   NZ_CP051711
Coordinates   2050740..2051399 (+) Length   219 a.a.
NCBI ID   WP_032153411.1    Uniprot ID   -
Organism   Escherichia coli strain SCU-123     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 2045740..2056399
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HHJ36_RS09765 (HHJ36_09765) ygiS 2047945..2049552 (-) 1608 WP_001350728.1 ABC transporter substrate-binding protein -
  HHJ36_RS09770 (HHJ36_09770) ygiV 2049661..2050143 (-) 483 WP_000183493.1 GyrI-like domain-containing protein -
  HHJ36_RS09775 (HHJ36_09775) ygiW 2050196..2050588 (-) 393 WP_000712658.1 OB fold stress tolerance protein YgiW -
  HHJ36_RS09780 (HHJ36_09780) ciaR 2050740..2051399 (+) 660 WP_032153411.1 quorum sensing response regulator transcription factor QseB Regulator
  HHJ36_RS09785 (HHJ36_09785) qseC 2051396..2052745 (+) 1350 WP_000673382.1 quorum sensing histidine kinase QseC -
  HHJ36_RS09790 (HHJ36_09790) ygiZ 2052791..2053121 (-) 331 Protein_1937 DUF2645 family protein -
  HHJ36_RS25940 - 2053128..2053838 (-) 711 WP_000834021.1 hypothetical protein -
  HHJ36_RS25945 - 2053841..2054374 (-) 534 WP_002430503.1 Hcp family type VI secretion system effector -
  HHJ36_RS09800 (HHJ36_09800) mdaB 2054624..2055205 (+) 582 WP_000065430.1 NADPH:quinone oxidoreductase MdaB -
  HHJ36_RS09805 (HHJ36_09805) ygiN 2055236..2055550 (+) 315 WP_000633738.1 putative quinol monooxygenase -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24686.69 Da        Isoelectric Point: 8.0731

>NTDB_id=387064 HHJ36_RS09780 WP_032153411.1 2050740..2051399(+) (ciaR) [Escherichia coli strain SCU-123]
MRILLIEDDMLIGDGIKTGLSKMGFSVDWFTQGRQGKEALYSAPYDAVILDLTLPGMDGRDILREWREKGQREPVLILTA
RDALAKRVEGLRLGADDYLCKPFALIEVAARLEALMRRTNGQASNELRHGNVMLDPGKRIATLAGEPLTLKPKEFALLEL
LMRNAGRVLPRKLIEEKLYTWDEEVTSNAVEVHVHHLRRKLGSDFIRTVHGIGYTLGEK

Nucleotide


Download         Length: 660 bp        

>NTDB_id=387064 HHJ36_RS09780 WP_032153411.1 2050740..2051399(+) (ciaR) [Escherichia coli strain SCU-123]
ATGCGAATTTTACTGATAGAAGATGACATGCTGATTGGCGACGGCATCAAAACGGGCCTTAGTAAAATGGGTTTTAGCGT
CGACTGGTTTACACAAGGTCGTCAGGGAAAAGAGGCGCTATATAGCGCACCTTATGATGCGGTGATCCTGGATTTAACCT
TACCGGGCATGGATGGTCGCGATATTTTGCGCGAATGGCGAGAAAAAGGTCAGCGTGAGCCGGTACTGATCCTGACCGCG
CGCGATGCGCTGGCGAAACGTGTAGAAGGGCTGCGTCTGGGAGCTGACGATTATCTGTGTAAACCTTTTGCGTTGATAGA
AGTCGCCGCCAGGCTGGAAGCTCTGATGCGCCGAACCAACGGCCAGGCCAGCAACGAGCTGCGCCACGGCAACGTCATGC
TCGACCCCGGCAAACGTATCGCCACGCTGGCTGGCGAACCCTTAACGCTGAAACCAAAAGAATTTGCCCTGCTGGAATTA
CTGATGCGTAACGCTGGTCGGGTACTGCCGCGCAAACTGATTGAAGAGAAACTGTATACCTGGGACGAAGAGGTCACCAG
TAATGCCGTTGAAGTGCATGTGCATCATCTGCGACGCAAACTCGGCAGTGATTTTATTCGTACCGTGCATGGTATTGGCT
ACACATTAGGTGAGAAATGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(3-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-216)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

38.326

100

0.397
  ciaR Streptococcus pneumoniae D39

38.326

100

0.397
  ciaR Streptococcus pneumoniae R6

38.326

100

0.397
  ciaR Streptococcus pneumoniae TIGR4

38.326

100

0.397
  ciaR Streptococcus mutans UA159

35.874

100

0.365