Detailed information NTG0387008

Bioinformatically predicted

Overview

• Name: pilR
• Type: Regulator
• Locus tag: FVA82_RS26890
• Genome accession: NZ_CP044006
• Coordinates: 5576414..5577751 (+)
• Length: 445 a.a.
• NCBI ID: WP_003094694.1
• Uniprot ID: A0A0H2ZG94
• Organism: Pseudomonas aeruginosa strain E90
• Function: regulate pilin expression (predicted from homology) Competence regulation

Genomic Context

Location: 5571414..5582751

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FVA82_RS26865 (FVA82_26865)	pgeF	5571557..5572285 (-)	729	WP_003102588.1	peptidoglycan editing factor PgeF	-
FVA82_RS26870 (FVA82_26870)	rluD	5572282..5573244 (-)	963	WP_003094686.1	23S rRNA pseudouridine(1911/1915/1917) synthase RluD	-
FVA82_RS26875 (FVA82_26875)	-	5573390..5574415 (+)	1026	WP_003102590.1	outer membrane protein assembly factor BamD	-
FVA82_RS26880 (FVA82_26880)	-	5574572..5574817 (+)	246	WP_003102591.1	PP0621 family protein	-
FVA82_RS26885 (FVA82_26885)	pilS	5574807..5576399 (+)	1593	WP_003094692.1	two-component system sensor histidine kinase PilS	Regulator
FVA82_RS26890 (FVA82_26890)	pilR	5576414..5577751 (+)	1338	WP_003094694.1	two-component system response regulator PilR	Regulator
FVA82_RS26895 (FVA82_26895)	thiO	5577797..5578891 (-)	1095	WP_020750388.1	glycine oxidase ThiO	-
FVA82_RS26900 (FVA82_26900)	-	5579026..5579535 (+)	510	WP_003102595.1	Tfp pilus assembly protein FimT/FimU	-
FVA82_RS26905 (FVA82_26905)	-	5579641..5580147 (+)	507	WP_003102598.1	Tfp pilus assembly protein FimT/FimU	-
FVA82_RS26910 (FVA82_26910)	pilV	5580138..5580695 (+)	558	WP_003102600.1	type 4a pilus minor pilin PilV	Machinery gene
FVA82_RS26915 (FVA82_26915)	pilW	5580692..5581516 (+)	825	WP_003119422.1	type 4a pilus minor pilin PilW	-
FVA82_RS26920 (FVA82_26920)	pilX	5581513..5582100 (+)	588	WP_003102605.1	type 4a pilus minor pilin PilX	-

Sequence

Protein

• Length: 445 a.a.
• Molecular weight: 49737.06 Da
• Isoelectric Point: 5.8654

>NTDB_id=387008 FVA82_RS26890 WP_003094694.1 5576414..5577751(+) (pilR) [Pseudomonas aeruginosa strain E90]
MSRQKALIVDDEPDIRELLEITLGRMKLDTRSARNVKEARELLAREPFDLCLTDMRLPDGSGLDLVQYIQQRHPQTPVAM
ITAYGSLDTAIQALKAGAFDFLTKPVDLGRLRELVATALRLRNPEAEEAPVDNRLLGESPPMRALRNQIGKLARSQAPVY
ISGESGSGKELVARLIHEQGPRIERPFVPVNCGAIPSELMESEFFGHKKGSFTGAIEDKQGLFQAASGGTLFLDEVADLP
MAMQVKLLRAIQEKAVRAVGGQQEVAVDVRILCATHKDLAAEVGAGRFRQDLYYRLNVIELRVPPLRERREDIPLLAERI
LKRLAGDTGLPAARLTGDAQEKLKNYRFPGNVRELENMLERAYTLCEDDQIQPHDLRLADAPGASQEGAASLSEIDNLED
YLEDIERKLIMQALEETRWNRTAAAQRLGLTFRSMRYRLKKLGID

Nucleotide

• Length: 1338 bp

>NTDB_id=387008 FVA82_RS26890 WP_003094694.1 5576414..5577751(+) (pilR) [Pseudomonas aeruginosa strain E90]
ATGAGCCGACAAAAAGCCCTGATCGTCGACGATGAACCGGATATCCGCGAACTGCTGGAAATCACTCTCGGCCGCATGAA
GCTGGACACCCGCAGCGCCCGCAACGTCAAGGAAGCCCGCGAGTTGCTGGCCCGCGAGCCGTTCGACCTGTGCCTCACCG
ACATGCGCCTGCCGGACGGCAGCGGCCTCGATCTGGTCCAGTACATCCAGCAGCGCCATCCACAGACCCCGGTGGCCATG
ATCACCGCGTACGGCAGCCTGGACACCGCGATCCAGGCGCTCAAGGCCGGTGCCTTCGACTTCCTCACCAAACCGGTCGA
CCTCGGTCGCTTGCGGGAGCTGGTGGCAACCGCCCTGCGCTTGCGCAACCCGGAAGCCGAGGAAGCGCCGGTGGACAACC
GCCTGCTCGGCGAGTCGCCGCCGATGCGCGCCCTGCGCAACCAGATCGGCAAGCTGGCGCGCAGCCAGGCGCCGGTCTAC
ATCAGTGGCGAGTCCGGTAGCGGCAAGGAGCTGGTGGCGCGCCTGATCCACGAGCAGGGGCCACGTATCGAGCGGCCGTT
CGTGCCGGTGAACTGCGGCGCGATTCCCTCCGAACTGATGGAAAGCGAGTTCTTCGGCCACAAGAAAGGCAGCTTCACTG
GCGCTATCGAAGACAAGCAGGGCCTGTTCCAGGCCGCCAGCGGCGGCACCCTGTTCCTCGACGAAGTCGCCGACCTGCCG
ATGGCCATGCAGGTCAAACTGCTCCGGGCGATCCAGGAAAAGGCCGTGCGCGCGGTCGGCGGCCAGCAGGAGGTCGCCGT
CGACGTGCGCATCCTCTGCGCCACCCACAAGGACCTCGCCGCCGAAGTCGGCGCCGGGCGCTTCCGCCAGGACCTCTACT
ACCGCCTCAACGTCATCGAGCTGCGCGTACCGCCGCTGCGCGAACGCCGCGAGGACATCCCGCTGCTCGCCGAACGCATC
CTCAAGCGCCTGGCCGGCGACACCGGCCTGCCGGCCGCCAGGCTGACCGGCGACGCACAGGAGAAGCTGAAGAACTACCG
CTTCCCGGGCAACGTCCGCGAGCTGGAAAACATGCTGGAGCGCGCCTACACCCTGTGCGAAGACGACCAGATCCAGCCTC
ACGACCTGCGCCTGGCCGATGCGCCGGGTGCCAGCCAGGAAGGCGCCGCGAGCCTGAGCGAAATAGACAACCTCGAGGAC
TACCTGGAAGACATCGAGCGCAAGCTGATCATGCAGGCGCTCGAGGAGACCCGCTGGAACCGCACCGCCGCGGCCCAGCG
CCTGGGCCTGACGTTCCGCTCGATGCGCTACCGCCTGAAAAAGCTGGGCATCGACTGA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (7-115)

• Sigma-54 interaction domain (Sigma54_activat) (135-301)

• Bacterial regulatory protein, Fis family (HTH_8) (402-442)

3D structure

• AlphaFold DB: A0A0H2ZG94

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilR	Pseudomonas aeruginosa PAK	100	100	1
pilR	Acinetobacter baumannii strain A118	51.198	100	0.528
luxO	Vibrio cholerae strain A1552	38.17	100	0.384