Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   F1614_RS11900 Genome accession   NZ_CP043847
Coordinates   2465146..2465775 (+) Length   209 a.a.
NCBI ID   WP_002473914.1    Uniprot ID   -
Organism   Staphylococcus epidermidis strain NCCP 16828     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2460146..2470775
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  F1614_RS11870 (F1614_11945) isaB 2460251..2460787 (+) 537 WP_017465007.1 immunodominant staphylococcal antigen IsaB family protein -
  F1614_RS11875 (F1614_11950) - 2460938..2461924 (-) 987 WP_002457091.1 FUSC family protein -
  F1614_RS11880 (F1614_11955) map 2462098..2462853 (+) 756 WP_002494126.1 type I methionyl aminopeptidase -
  F1614_RS11885 (F1614_11960) - 2463011..2463397 (+) 387 WP_017465009.1 hypothetical protein -
  F1614_RS11890 (F1614_11965) liaF 2463412..2464113 (+) 702 WP_002473931.1 cell wall-active antibiotics response protein LiaF -
  F1614_RS11895 (F1614_11970) vraS 2464110..2465156 (+) 1047 WP_002494127.1 sensor histidine kinase Regulator
  F1614_RS11900 (F1614_11975) vraR 2465146..2465775 (+) 630 WP_002473914.1 two-component system response regulator VraR Regulator
  F1614_RS11905 (F1614_11980) - 2465832..2467010 (-) 1179 WP_021298785.1 YihY/virulence factor BrkB family protein -
  F1614_RS11910 (F1614_11985) - 2467417..2467701 (-) 285 WP_002473916.1 YtxH domain-containing protein -
  F1614_RS11915 (F1614_11990) - 2467709..2468173 (-) 465 WP_002498659.1 low molecular weight protein-tyrosine-phosphatase -
  F1614_RS11920 (F1614_11995) - 2468314..2468529 (+) 216 WP_001830421.1 DUF1128 domain-containing protein -
  F1614_RS11925 (F1614_12000) - 2468531..2469772 (+) 1242 WP_017465013.1 aminopeptidase -
  F1614_RS11930 (F1614_12005) - 2469852..2470382 (+) 531 WP_002447436.1 acyl-CoA thioesterase -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23598.22 Da        Isoelectric Point: 4.7218

>NTDB_id=386258 F1614_RS11900 WP_002473914.1 2465146..2465775(+) (vraR) [Staphylococcus epidermidis strain NCCP 16828]
MAIKVLFVDDHEMVRIGISSYLSTQEDIEVVGEGASGKEAITKAHELKPDLILMDLLMDDMDGVEATTEIKKDLPQIKVV
MLTSFIEDKEVYRALDSGVDSYILKTTSASDIADAVRKTYEGESVFEPEVLVKMRNRMKKRAELYEMLTEREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=386258 F1614_RS11900 WP_002473914.1 2465146..2465775(+) (vraR) [Staphylococcus epidermidis strain NCCP 16828]
GTGGCGATTAAAGTTTTATTTGTTGATGATCATGAAATGGTAAGAATCGGTATTTCAAGCTATCTTTCAACTCAAGAAGA
TATAGAAGTAGTAGGTGAGGGTGCTTCTGGTAAAGAGGCTATCACTAAAGCGCATGAGCTAAAACCAGATTTAATATTAA
TGGATTTACTTATGGACGATATGGATGGTGTAGAAGCAACTACTGAAATTAAAAAAGATTTACCTCAAATTAAAGTAGTC
ATGTTAACAAGCTTTATAGAGGATAAAGAAGTTTATCGTGCACTTGATTCTGGAGTAGATAGTTATATTTTAAAGACAAC
AAGTGCAAGTGATATAGCTGACGCTGTGCGTAAAACGTATGAAGGTGAATCAGTATTTGAACCAGAAGTGTTAGTAAAAA
TGCGCAACCGTATGAAAAAACGTGCCGAGCTTTATGAAATGTTAACAGAAAGAGAAATGGAGATCCTATTACTTATAGCT
AAAGGATACTCTAACCAAGAGATTGCAAGCGCCTCTCATATCACCATCAAAACAGTAAAAACTCATGTAAGTAACATACT
GAGTAAATTAGAAGTTCAAGATCGAACACAAGCAGTAATCTATGCGTTCCAGCATAATTTAATTCAATAA

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, luxR family (GerE)

(147-202)

Response regulator receiver domain (Response_reg)

(5-116)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

95.215

100

0.952
  degU Bacillus subtilis subsp. subtilis str. 168

34.821

100

0.373

Multiple sequence alignment