Detailed information NTG0386257

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: F1614_RS11895
• Genome accession: NZ_CP043847
• Coordinates: 2464110..2465156 (+)
• Length: 348 a.a.
• NCBI ID: WP_002494127.1
• Uniprot ID: -
• Organism: Staphylococcus epidermidis strain NCCP 16828
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2459110..2470156

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
F1614_RS11870 (F1614_11945)	isaB	2460251..2460787 (+)	537	WP_017465007.1	immunodominant staphylococcal antigen IsaB family protein	-
F1614_RS11875 (F1614_11950)	-	2460938..2461924 (-)	987	WP_002457091.1	FUSC family protein	-
F1614_RS11880 (F1614_11955)	map	2462098..2462853 (+)	756	WP_002494126.1	type I methionyl aminopeptidase	-
F1614_RS11885 (F1614_11960)	-	2463011..2463397 (+)	387	WP_017465009.1	hypothetical protein	-
F1614_RS11890 (F1614_11965)	liaF	2463412..2464113 (+)	702	WP_002473931.1	cell wall-active antibiotics response protein LiaF	-
F1614_RS11895 (F1614_11970)	vraS	2464110..2465156 (+)	1047	WP_002494127.1	sensor histidine kinase	Regulator
F1614_RS11900 (F1614_11975)	vraR	2465146..2465775 (+)	630	WP_002473914.1	two-component system response regulator VraR	Regulator
F1614_RS11905 (F1614_11980)	-	2465832..2467010 (-)	1179	WP_021298785.1	YihY/virulence factor BrkB family protein	-
F1614_RS11910 (F1614_11985)	-	2467417..2467701 (-)	285	WP_002473916.1	YtxH domain-containing protein	-
F1614_RS11915 (F1614_11990)	-	2467709..2468173 (-)	465	WP_002498659.1	low molecular weight protein-tyrosine-phosphatase	-
F1614_RS11920 (F1614_11995)	-	2468314..2468529 (+)	216	WP_001830421.1	DUF1128 domain-containing protein	-
F1614_RS11925 (F1614_12000)	-	2468531..2469772 (+)	1242	WP_017465013.1	aminopeptidase	-

Sequence

Protein

• Length: 348 a.a.
• Molecular weight: 39994.42 Da
• Isoelectric Point: 6.0544

>NTDB_id=386257 F1614_RS11895 WP_002494127.1 2464110..2465156(+) (vraS) [Staphylococcus epidermidis strain NCCP 16828]
MNHYIRAIGSMLILVYSMLIAFLFIDKVFVNIIFFQGMFYTQIFGIPVFLFLNLLIVLLCIIVGSVLAYKINQQNDWIIS
QIERSIEGQTVGINDQNIELYTETIDIYHTLVPLNQELHRLRMKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKESKLEPPLNQQIPILEKMVQDSQLEMRALLLHLRPIGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFEVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNQGDYLLLRIQDNGKGFNVDEKFEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEENSSGD

Nucleotide

• Length: 1047 bp

>NTDB_id=386257 F1614_RS11895 WP_002494127.1 2464110..2465156(+) (vraS) [Staphylococcus epidermidis strain NCCP 16828]
ATGAATCACTACATAAGAGCTATAGGCTCAATGCTTATATTAGTATATAGTATGCTTATTGCTTTTTTATTTATTGATAA
AGTGTTTGTAAATATTATCTTTTTTCAGGGGATGTTTTATACACAAATATTTGGAATACCTGTTTTTCTATTTTTAAATT
TATTAATTGTTCTTTTATGTATTATAGTTGGATCTGTTTTAGCTTATAAAATTAATCAACAAAATGATTGGATTATTTCA
CAAATAGAAAGATCAATAGAAGGACAAACGGTAGGTATCAATGATCAAAATATCGAATTATATACAGAAACGATAGATAT
TTATCATACACTAGTTCCATTAAATCAAGAATTACATCGACTTAGAATGAAGACTCAAAATTTAACTAATGAAAACTACA
ACATTAATGATGTAAAAGTCAAAAAGATTATCGAAGATGAGCGACAACGACTTGCCAGGGAATTACATGATTCTGTTAGT
CAACAATTATTTGCTGCGAGCATGATGCTATCAGCGATAAAAGAGTCGAAATTAGAACCACCTTTAAATCAACAGATACC
AATTCTTGAAAAAATGGTTCAAGACTCACAACTTGAAATGAGAGCTTTGTTGTTACATTTAAGACCGATAGGTTTAAAAG
ATAAGTCTTTAGGTGAAGGAATTAAAGATTTAGTCATCGATTTACAAAAGAAAGTACCAATGAAAGTTGTGCATGAAATT
CAAGATTTTGAAGTGCCAAAAGGCATTGAAGATCATTTGTTCAGAATTACACAAGAAGCTATTTCAAATACATTGAGACA
TTCAAATGGTACAAAAGTAACTGTGGAATTATTTAATCAAGGGGATTATCTTTTACTAAGAATTCAAGATAATGGAAAAG
GGTTTAATGTAGATGAAAAATTTGAACAAAGTTATGGTTTGAAAAATATGCGAGAACGAGCGTTAGAAATTGGTGCGACG
TTTCATATTGTATCTTTACCTGATTCAGGTACACGAATTGAAGTTAAGGCACCATTGAATAAGGAGGAGAATTCAAGTGG
CGATTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	93.023	98.851	0.92