Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilD   Type   Machinery gene
Locus tag   F1537_RS04545 Genome accession   NZ_CP043770
Coordinates   858632..859324 (+) Length   230 a.a.
NCBI ID   WP_013525531.1    Uniprot ID   A0AAV2U3Y4
Organism   Haemophilus influenzae biotype aegyptius strain HE7/F1946     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 853632..864324
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  F1537_RS04525 (F1537_04535) ampD 854906..855466 (-) 561 WP_006996183.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  F1537_RS04530 (F1537_04540) pilA 855581..856030 (+) 450 WP_006996184.1 prepilin-type N-terminal cleavage/methylation domain-containing protein Machinery gene
  F1537_RS04535 (F1537_04545) pilB 856027..857421 (+) 1395 WP_013525533.1 GspE/PulE family protein Machinery gene
  F1537_RS04540 (F1537_04550) pilC 857418..858635 (+) 1218 WP_013525532.1 type II secretion system F family protein Machinery gene
  F1537_RS04545 (F1537_04555) pilD 858632..859324 (+) 693 WP_013525531.1 A24 family peptidase Machinery gene
  F1537_RS04550 (F1537_04560) rho 859379..860641 (-) 1263 WP_005666690.1 transcription termination factor Rho -
  F1537_RS04555 (F1537_04565) metJ 860889..861206 (+) 318 WP_005631186.1 met regulon transcriptional regulator MetJ -
  F1537_RS04560 (F1537_04570) cueR 861220..861606 (-) 387 WP_005648963.1 Cu(I)-responsive transcriptional regulator -
  F1537_RS04565 (F1537_04575) - 861683..861889 (+) 207 WP_013525530.1 heavy-metal-associated domain-containing protein -
  F1537_RS04570 (F1537_04580) - 861964..862170 (+) 207 WP_005666693.1 heavy-metal-associated domain-containing protein -
  F1537_RS04580 (F1537_04590) - 862256..862462 (+) 207 WP_005631184.1 heavy-metal-associated domain-containing protein -

Sequence

Protein


Download         Length: 230 a.a.        Molecular weight: 26800.82 Da        Isoelectric Point: 8.8532

>NTDB_id=385770 F1537_RS04545 WP_013525531.1 858632..859324(+) (pilD) [Haemophilus influenzae biotype aegyptius strain HE7/F1946]
MIYFTMFLLGGIFGIALWFYLSGFITRLQQEIYATYIELFPQNFLPFQSSVSSIQQKKCGHILRYFLSVGVGFIFLQIAF
KDSIFTVWFGLTLLILWAISYLDWHYQLISTTLCLWLLTIGLFGADNNFSLLTLSESIKSAASFFIVFYAIYWIAKFYYG
KEAFGRGDYWLAMALGSFIQLETLPHFLLLASVLGICFSLIHKKKKEFIPFAPFMNLSAVIIYFVKYYWY

Nucleotide


Download         Length: 693 bp        

>NTDB_id=385770 F1537_RS04545 WP_013525531.1 858632..859324(+) (pilD) [Haemophilus influenzae biotype aegyptius strain HE7/F1946]
ATGATTTACTTCACAATGTTTTTATTAGGCGGCATCTTCGGGATCGCATTGTGGTTCTACCTATCTGGTTTTATTACCCG
TTTACAGCAAGAGATTTATGCGACTTATATTGAATTATTCCCACAAAACTTTCTGCCATTTCAGTCTAGCGTTTCCTCTA
TTCAACAAAAAAAGTGCGGTCATATTTTGAGGTATTTTTTAAGTGTTGGGGTAGGATTTATATTTTTACAAATTGCCTTC
AAAGATTCTATTTTTACTGTATGGTTCGGACTCACACTTCTTATCCTTTGGGCAATCAGTTATCTTGATTGGCACTATCA
ACTTATTTCTACTACACTCTGTTTATGGTTACTTACAATCGGTTTATTTGGGGCAGACAATAACTTTTCATTGCTTACGT
TATCTGAAAGCATAAAAAGTGCGGCAAGTTTTTTTATTGTTTTCTACGCAATCTATTGGATTGCAAAATTCTATTACGGA
AAAGAAGCCTTTGGACGGGGAGATTATTGGCTAGCAATGGCATTAGGAAGTTTTATTCAGTTAGAAACCTTACCGCACTT
TTTATTATTAGCCTCAGTTCTTGGAATATGTTTTTCGCTTATTCATAAAAAGAAAAAAGAATTTATACCTTTTGCCCCTT
TTATGAACTTATCAGCTGTCATAATTTATTTCGTCAAATATTACTGGTATTAA

Domains

Predicted by InterproScan.

Type IV leader peptidase family (Peptidase_A24)

(92-199)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilD Haemophilus influenzae 86-028NP

90.435

100

0.904
  pilD Haemophilus influenzae Rd KW20

90

100

0.9

Multiple sequence alignment