Detailed information NTG0385444

Bioinformatically predicted

Overview

• Name: comB4
• Type: Machinery gene
• Locus tag: HG575_RS04735
• Genome accession: NZ_CP051540
• Coordinates: 1005281..1007845 (+)
• Length: 854 a.a.
• NCBI ID: WP_202247581.1
• Uniprot ID: -
• Organism: Helicobacter pylori strain LIM-002
• Function: transformation-associated type IV transport system (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1000281..1012845

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HG575_RS04700 (HG575_04700)	-	1001207..1002916 (-)	1710	Protein_926	dynamin family protein	-
HG575_RS04705 (HG575_04705)	-	1002970..1003758 (+)	789	WP_202247571.1	integrase	-
HG575_RS04710 (HG575_04710)	-	1003779..1003985 (+)	207	WP_237419588.1	hypothetical protein	-
HG575_RS04715 (HG575_04715)	-	1003982..1004461 (+)	480	WP_202247575.1	hypothetical protein	-
HG575_RS04720 (HG575_04720)	comB2	1004458..1004748 (+)	291	WP_202247577.1	TrbC/VirB2 family protein	Machinery gene
HG575_RS04725 (HG575_04725)	comB3	1004770..1005033 (+)	264	WP_001177721.1	hypothetical protein	Machinery gene
HG575_RS04730 (HG575_04730)	-	1005045..1005281 (+)	237	WP_202247579.1	hypothetical protein	-
HG575_RS04735 (HG575_04735)	comB4	1005281..1007845 (+)	2565	WP_202247581.1	VirB4 family type IV secretion/conjugal transfer ATPase	Machinery gene
HG575_RS04740 (HG575_04740)	-	1007847..1007981 (+)	135	WP_078265615.1	type IV secretion system protein VirB7	-
HG575_RS04745 (HG575_04745)	-	1007974..1009140 (+)	1167	WP_202247583.1	VirB8/TrbF family protein	-
HG575_RS04750 (HG575_04750)	-	1009137..1010741 (+)	1605	WP_202247585.1	TrbG/VirB9 family P-type conjugative transfer protein	-
HG575_RS04755 (HG575_04755)	comB10	1010738..1011937 (+)	1200	WP_202247587.1	DNA type IV secretion system protein ComB10	Machinery gene

Sequence

Protein

• Length: 854 a.a.
• Molecular weight: 98311.35 Da
• Isoelectric Point: 8.7558

>NTDB_id=385444 HG575_RS04735 WP_202247581.1 1005281..1007845(+) (comB4) [Helicobacter pylori strain LIM-002]
MLENAFKYCKEKAIELLTGFVPKTYSMAEECNILGLYDDTFIITKQENLVAIMSLQGLSYSNLMQKDLEGYFDIRQNVLN
TISKDIQLRIVAKRRKEFINQSPNIDNPYAKAIITQFESKEIYKTEYFLVFESITSNVKSFFEKKKLEMTTSINEELEES
SKENENNSNETHSNTSSKKDKKNKFKKKTTFSATSKRALLIQTIERVKNALREFKPTLLNSKEVLNFYAEYINGKYIAFN
PKLKRLSDSYIASNVHFKKDYFVIEFQNQSTFCACVGIKNYESEEISSLPISTLLHTQIELDLIFHIRSLGQFESLNFLK
TKKKLTLSKMVKNDIDDYIELVQANRLSMQECALNLVIRAKSKAKLDKSLKEILSLLNNAGLGSVTETIGLKPSYFSFFP
NNANINPRMRNQTSQVIASLILFEKNNTGFRANSWGDMPLSVFKNLDYSPYLFNFHNQEVKHKGVLAHNVARVVGHTMII
GATGAGKTTLISYLMMSALKYSNIDILALDRLNGLYSFTKYFDGIYNQGENFHINPFSLEDSATNRAFLLHFYAQMAKVD
SYDDHKDKVEDKTALINAIDTMYRNYNDEVKQAKFSNQELPLPFDLKEFVNTIVKTNTNILDSSFEDYLKSSLFSSRMDS
LDFKTRISTINTDSILHNDDNAGLLAYYVFHKMIDRALKINRGFLCFIDEFKSYAQNEMMNKKINEIITQARKANGVIVL
ALQDINQLTEVRNAQSFIKNMGQLILYPQRNIDTKDLNDKFGIRLSDTEKHFLENTAVNEYKVLLKNMNDGSSNIIDVSL
SSLGNYLQIFSSNSSMVEHIENLIKHYPTTWREVFVNNTYQKFDDKKHLEKVLA

Nucleotide

• Length: 2565 bp

>NTDB_id=385444 HG575_RS04735 WP_202247581.1 1005281..1007845(+) (comB4) [Helicobacter pylori strain LIM-002]
ATGCTAGAAAACGCTTTTAAATATTGCAAAGAGAAAGCCATAGAGCTTTTAACAGGTTTTGTGCCAAAAACCTATTCTAT
GGCAGAGGAATGCAATATTTTAGGCTTGTATGATGATACTTTTATTATCACCAAACAAGAAAATTTAGTCGCTATTATGT
CTTTACAAGGACTAAGTTATTCTAATTTAATGCAAAAAGATTTGGAGGGCTATTTTGATATAAGACAAAATGTTCTCAAT
ACCATTAGTAAAGACATTCAATTAAGGATTGTGGCTAAAAGGCGTAAAGAATTTATCAATCAAAGCCCCAACATTGACAA
CCCTTATGCCAAAGCCATTATCACACAATTTGAAAGCAAGGAAATCTATAAAACAGAATATTTTTTAGTGTTTGAGAGCA
TTACTTCTAATGTCAAATCTTTCTTTGAGAAAAAGAAATTAGAAATGACTACTTCAATCAATGAAGAATTAGAAGAAAGC
TCTAAAGAGAATGAAAATAACTCCAATGAGACCCATTCAAACACAAGCTCTAAAAAAGACAAGAAAAACAAGTTCAAAAA
AAAGACAACCTTTAGCGCCACAAGTAAAAGAGCCTTACTCATTCAAACCATAGAAAGAGTGAAAAACGCATTAAGAGAGT
TTAAACCCACTCTCTTAAATTCTAAAGAAGTGTTGAATTTCTATGCGGAGTATATCAATGGCAAATACATCGCCTTTAAT
CCTAAACTAAAGCGACTAAGCGATAGCTATATTGCTAGTAATGTGCATTTTAAAAAAGATTACTTTGTCATTGAATTTCA
AAATCAAAGCACCTTTTGTGCGTGTGTGGGTATCAAAAACTATGAGAGTGAAGAAATTTCTTCTCTCCCCATTTCTACCC
TTTTACACACGCAAATTGAATTAGATTTAATCTTTCATATCCGTTCATTAGGGCAGTTTGAAAGCTTGAATTTTCTAAAA
ACCAAGAAAAAACTCACGCTTTCTAAAATGGTGAAAAATGATATTGATGATTATATAGAATTGGTGCAAGCCAATCGTTT
GAGTATGCAAGAGTGCGCCTTAAACTTAGTTATAAGAGCTAAGAGCAAAGCCAAATTAGACAAATCTTTAAAAGAGATTT
TATCCTTGCTTAATAACGCTGGACTAGGCAGTGTTACAGAAACCATAGGGCTAAAACCCTCTTATTTTTCATTCTTCCCT
AATAATGCAAACATTAACCCTAGAATGAGAAATCAAACTTCCCAAGTGATAGCCTCTTTAATCTTGTTTGAAAAAAATAA
TACAGGTTTTAGGGCAAATTCTTGGGGTGATATGCCTTTATCTGTGTTTAAGAACCTAGACTATAGCCCTTATTTGTTTA
ACTTCCACAACCAAGAAGTCAAACATAAAGGCGTGTTAGCCCATAATGTTGCACGAGTGGTAGGGCATACGATGATTATA
GGAGCAACAGGAGCTGGTAAAACCACGCTCATTAGCTATCTAATGATGAGTGCTTTAAAATACTCTAACATTGATATTCT
AGCTCTTGATAGATTAAATGGTTTGTATTCTTTTACCAAGTATTTTGATGGGATTTATAATCAAGGCGAAAACTTTCATA
TTAACCCTTTTTCATTAGAAGATAGCGCAACTAATAGAGCCTTTTTATTGCATTTTTATGCCCAAATGGCAAAAGTGGAT
AGCTATGATGACCATAAAGATAAAGTAGAAGATAAAACAGCCCTAATAAATGCTATTGATACCATGTATAGAAATTATAA
CGATGAAGTCAAACAAGCCAAATTTAGTAACCAAGAATTACCCCTTCCTTTTGATTTAAAAGAGTTTGTCAATACCATCG
TTAAAACCAATACAAACATTTTAGATAGTAGTTTTGAAGACTATTTAAAATCTTCCTTATTTTCTAGCCGAATGGATAGC
CTAGATTTTAAAACTCGCATTAGCACCATAAATACCGATAGCATTTTACATAATGATGATAACGCTGGGCTTTTAGCCTA
CTATGTGTTTCATAAGATGATTGATAGAGCCTTGAAAATCAATCGTGGTTTTTTATGCTTTATTGATGAGTTTAAATCTT
ACGCTCAAAATGAAATGATGAATAAAAAAATCAATGAAATCATTACCCAAGCCAGAAAGGCTAATGGGGTGATTGTTCTA
GCCTTACAAGACATCAACCAGCTAACTGAAGTGAGAAACGCTCAAAGCTTTATTAAAAATATGGGGCAGTTGATTTTGTA
TCCCCAAAGAAATATTGATACCAAAGATTTAAACGATAAATTTGGCATTAGACTGAGCGATACTGAAAAGCATTTTTTAG
AAAACACCGCCGTTAATGAATATAAAGTCTTACTCAAAAACATGAATGATGGCTCATCTAATATTATAGATGTGAGCCTT
AGCTCTTTGGGTAATTACTTACAAATCTTTAGCTCTAATTCTAGCATGGTAGAACACATTGAAAATCTCATTAAGCATTA
CCCTACTACTTGGAGAGAAGTCTTTGTCAATAATACCTATCAAAAATTTGATGATAAAAAACACTTAGAAAAAGTGCTTG
CCTAA

Domains

Predicted by InterProScan.

• CagE, TrbE, VirB family, component of type IV transporter system (CagE_TrbE_VirB) (210-408)

• FtsK/SpoIIIE family (FtsK_SpoIIIE) (435-501)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comB4	Helicobacter pylori 26695	47.249	97.892	0.463