Detailed information NTG0385271

Bioinformatically predicted

Overview

• Name: comB4
• Type: Machinery gene
• Locus tag: HG581_RS02270
• Genome accession: NZ_CP051535
• Coordinates: 472202..474766 (+)
• Length: 854 a.a.
• NCBI ID: WP_202138301.1
• Uniprot ID: -
• Organism: Helicobacter pylori strain LIM-008
• Function: transformation-associated type IV transport system (predicted from homology) DNA binding and uptake

Genomic Context

Location: 467202..479766

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HG581_RS02235 (HG581_02230)	hofD	468442..469839 (+)	1398	WP_120895870.1	outer membrane beta-barrel protein HofD	-
HG581_RS02240 (HG581_02235)	-	469903..470691 (+)	789	WP_202138296.1	integrase	-
HG581_RS02245 (HG581_02240)	-	470694..470918 (+)	225	WP_202138297.1	hypothetical protein	-
HG581_RS02250 (HG581_02245)	-	470915..471394 (+)	480	WP_202138298.1	hypothetical protein	-
HG581_RS02255 (HG581_02250)	comB2	471391..471681 (+)	291	WP_202138299.1	TrbC/VirB2 family protein	Machinery gene
HG581_RS02260 (HG581_02255)	comB3	471691..471954 (+)	264	WP_001177721.1	hypothetical protein	Machinery gene
HG581_RS02265 (HG581_02260)	-	471966..472202 (+)	237	WP_202138300.1	hypothetical protein	-
HG581_RS02270 (HG581_02265)	comB4	472202..474766 (+)	2565	WP_202138301.1	VirB4 family type IV secretion/conjugal transfer ATPase	Machinery gene
HG581_RS07945	-	474768..474902 (+)	135	WP_077654653.1	type IV secretion system protein VirB7	-
HG581_RS02275 (HG581_02270)	-	474895..476061 (+)	1167	WP_202138302.1	VirB8/TrbF family protein	-
HG581_RS02280 (HG581_02275)	-	476058..477689 (+)	1632	WP_202138303.1	TrbG/VirB9 family P-type conjugative transfer protein	-
HG581_RS02285 (HG581_02280)	comB10	477686..478885 (+)	1200	WP_202138304.1	DNA type IV secretion system protein ComB10	Machinery gene

Sequence

Protein

• Length: 854 a.a.
• Molecular weight: 98270.21 Da
• Isoelectric Point: 8.6400

>NTDB_id=385271 HG581_RS02270 WP_202138301.1 472202..474766(+) (comB4) [Helicobacter pylori strain LIM-008]
MLENAFKYCKEKAIELLTGFVPKTYSMAEECNILGLYDDTFIITKQENLVAIMSLQGLSYSNLMQKDLEGYFDTRQNVLN
TISKDIQLRIVAKRRKEFINQSPNIDNPYAKAIITQFESKEIYKTEYFLVFESITSNVKSFFEKKKLEMTTSINEELEES
SKENENNSNETHSNTSSKKDKKNKFKKKTTFSATSKRALLIQTIERVKNALREFKPTLLNSKEVLNFYAEYINGKYIAFN
PKLKRLSDSYIASNVHFKKDYFVIEFQNQSTFCACVGIKNYESEEISSLPISTLLHTQIELDLIFHIRSLGQFESLNFLK
TKKKLTLSKMVKNDIDDYIELVQANRLSMQECALNLVIRAKSKAKLDKSLKEILSLLNNAGLGSVTETIGLKPSYFSFFP
NNANINPRMRNQTSQVIASLILFEKNNTGFRANSWGDMPLSVFKNLDHSPYLFNFHNQEVKHKGVLAHNVARVVGHTMII
GATGAGKTTLISYLMMSALKYSNIDILALDRLNGLYSFTKYFDGIYNQGENFHINPFSLEDSATNRAFLLHFYAQMAKVD
SYDDHKDKVEDKTALINAIDTMYRNYNDEVKQAKFSNQELPLPFDLKEFVNAIVKTNTNILDSSFEDYLKSPLFSSRMDS
LDFRTRISTINTDSILHNDDNAGLLAYYVFHKMIDRALKINRGFLCFIDEFKSYAQNEMMNKKINEIITQARKANGVIVL
ALQDINQLTEVRNAQSFIKNMGQLILYPQRNIDTKDLNDKFGIRLSDTEKHFLENTAVNEYKVLLKNMNDGSSNIIDVSL
SSLGNYLQIFSSNSSMVEHIENLIKHYPTTWREVFVNNTYQKFDDKKHLETVLS

Nucleotide

• Length: 2565 bp

>NTDB_id=385271 HG581_RS02270 WP_202138301.1 472202..474766(+) (comB4) [Helicobacter pylori strain LIM-008]
ATGCTAGAAAACGCTTTTAAATATTGCAAAGAGAAAGCCATAGAGCTTTTAACAGGTTTTGTGCCAAAAACCTATTCTAT
GGCAGAGGAATGCAATATTTTAGGCTTGTATGATGATACTTTTATTATCACCAAACAAGAAAATTTAGTCGCTATTATGT
CTTTACAAGGACTAAGTTATTCTAATTTAATGCAAAAAGATTTGGAGGGCTATTTTGATACAAGACAAAATGTTCTCAAT
ACCATTAGTAAGGACATTCAATTAAGGATTGTGGCTAAAAGGCGTAAAGAATTTATCAATCAAAGCCCCAACATTGACAA
CCCTTATGCCAAAGCCATTATCACACAATTTGAAAGCAAGGAAATCTATAAAACAGAATATTTTTTAGTGTTTGAGAGCA
TTACTTCTAATGTCAAATCTTTCTTTGAGAAAAAGAAATTAGAAATGACTACTTCAATCAATGAAGAATTAGAAGAAAGC
TCTAAAGAGAATGAAAATAACTCCAATGAGACCCATTCAAACACAAGCTCTAAAAAAGACAAGAAAAACAAGTTCAAAAA
AAAGACAACCTTTAGCGCCACAAGTAAAAGAGCCTTACTCATTCAAACCATAGAAAGAGTGAAAAACGCATTAAGAGAGT
TTAAACCCACTCTCTTAAATTCTAAAGAAGTGTTGAATTTCTATGCGGAGTATATCAATGGCAAATACATCGCCTTTAAT
CCTAAATTAAAGCGACTAAGCGATAGCTATATTGCTAGTAATGTGCATTTTAAAAAAGATTACTTTGTCATTGAATTTCA
AAATCAAAGCACCTTTTGTGCGTGTGTGGGTATCAAAAACTATGAGAGTGAAGAAATTTCTTCTCTCCCAATTTCTACCC
TTTTACACACGCAAATTGAATTAGATTTAATCTTTCATATCCGTTCATTAGGGCAGTTTGAAAGCTTGAATTTTCTAAAA
ACCAAGAAAAAACTCACGCTTTCTAAAATGGTGAAAAATGATATTGATGATTATATAGAATTGGTGCAAGCCAATCGTTT
GAGTATGCAAGAGTGCGCCTTAAACTTAGTTATAAGAGCTAAGAGCAAAGCCAAATTAGACAAATCTTTAAAAGAGATTT
TATCCTTGCTTAATAACGCTGGACTAGGCAGTGTTACAGAAACCATAGGGCTAAAACCCTCTTATTTTTCATTCTTCCCT
AATAATGCAAACATTAACCCTAGAATGAGAAATCAAACTTCCCAAGTGATAGCCTCTTTAATCTTGTTTGAAAAAAATAA
TACAGGTTTTAGGGCAAATTCTTGGGGCGATATGCCTCTATCTGTGTTTAAGAACCTAGACCATAGCCCTTATTTGTTTA
ACTTCCACAACCAAGAAGTCAAACATAAAGGCGTGTTAGCCCATAATGTTGCACGAGTGGTAGGGCATACGATGATTATA
GGAGCAACAGGAGCTGGTAAAACCACGCTCATTAGCTATCTAATGATGAGCGCTTTAAAATACTCTAACATTGATATTCT
AGCTCTTGATAGATTAAATGGTTTGTATTCTTTTACCAAGTATTTTGATGGGATTTATAATCAAGGCGAAAACTTTCATA
TTAACCCTTTTTCATTAGAAGATAGTGCAACTAATAGAGCCTTTTTATTGCATTTTTATGCCCAAATGGCAAAAGTGGAT
AGCTATGATGACCATAAAGATAAAGTAGAAGATAAAACAGCCCTAATAAATGCTATTGATACCATGTACAGAAATTATAA
CGATGAAGTCAAACAAGCCAAATTTAGCAACCAGGAATTACCCCTTCCTTTTGATTTAAAAGAGTTTGTCAATGCCATTG
TTAAAACCAATACAAACATTTTAGATAGTAGTTTTGAAGACTATTTAAAATCTCCCTTATTTTCTAGCCGAATGGATAGC
CTAGATTTTAGAACTCGTATTAGCACCATAAATACCGATAGCATTTTACACAATGATGATAACGCTGGGCTTTTAGCCTA
CTATGTGTTTCATAAGATGATTGATAGAGCCTTGAAAATCAATCGTGGTTTTTTATGCTTTATTGACGAATTTAAATCTT
ACGCTCAAAATGAAATGATGAATAAAAAAATCAATGAAATCATTACTCAAGCCAGAAAGGCTAATGGAGTGATTGTTCTA
GCCTTACAAGACATTAACCAGCTAACTGAAGTGAGAAACGCTCAAAGCTTTATTAAAAATATGGGGCAGTTGATTTTGTA
TCCCCAAAGAAATATTGATACCAAAGATTTAAACGATAAATTTGGCATTAGACTGAGCGATACTGAAAAGCATTTTTTAG
AAAACACCGCCGTTAATGAATACAAAGTCTTGCTTAAAAACATGAATGATGGCTCATCTAATATTATAGATGTGAGCCTT
AGTTCTTTGGGTAATTACTTACAAATCTTTAGCTCCAATTCTAGCATGGTAGAACATATTGAAAATCTCATTAAACATTA
CCCTACTACTTGGAGAGAAGTCTTTGTCAATAACACCTATCAAAAATTTGATGATAAAAAACACTTAGAAACGGTGCTTT
CCTAA

Domains

Predicted by InterProScan.

• FtsK/SpoIIIE family (FtsK_SpoIIIE) (433-501)

• CagE, TrbE, VirB family, component of type IV transporter system (CagE_TrbE_VirB) (210-408)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comB4	Helicobacter pylori 26695	47.129	97.892	0.461