Detailed information NTG0385135

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: EVS87_RS16830
• Genome accession: NZ_CP043559
• Coordinates: 3219113..3220288 (-)
• Length: 391 a.a.
• NCBI ID: WP_024719243.1
• Uniprot ID: A0A081LEM4
• Organism: Bacillus altitudinis strain CHB19
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3214113..3225288

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EVS87_RS16800 (EVS87_016800)	-	3214291..3214710 (-)	420	WP_017357864.1	TIGR03826 family flagellar region protein	-
EVS87_RS16805 (EVS87_016805)	-	3214767..3215489 (-)	723	WP_285891443.1	ComF family protein	-
EVS87_RS16810 (EVS87_016810)	-	3215450..3215743 (-)	294	WP_008348267.1	late competence development ComFB family protein	-
EVS87_RS16815 (EVS87_016815)	comFA	3215808..3217187 (-)	1380	WP_149712602.1	DEAD/DEAH box helicase	Machinery gene
EVS87_RS16820 (EVS87_016820)	-	3217307..3218149 (-)	843	WP_024719242.1	DegV family protein	-
EVS87_RS16825 (EVS87_016825)	degU	3218360..3219049 (-)	690	WP_008348273.1	two-component system response regulator DegU	Regulator
EVS87_RS16830 (EVS87_016830)	degS	3219113..3220288 (-)	1176	WP_024719243.1	sensor histidine kinase	Regulator
EVS87_RS16835 (EVS87_016835)	-	3220510..3221178 (+)	669	WP_017357860.1	YigZ family protein	-
EVS87_RS16840 (EVS87_016840)	-	3221163..3222260 (+)	1098	WP_024719244.1	LCP family protein	-
EVS87_RS16845 (EVS87_016845)	-	3222298..3223365 (-)	1068	WP_024719245.1	glycosyltransferase family 4 protein	-
EVS87_RS16850 (EVS87_016850)	tuaH	3223500..3224747 (-)	1248	WP_135009632.1	teichuronic acid biosynthesis protein TuaH	-

Sequence

Protein

• Length: 391 a.a.
• Molecular weight: 45550.27 Da
• Isoelectric Point: 5.8757

>NTDB_id=385135 EVS87_RS16830 WP_024719243.1 3219113..3220288(-) (degS) [Bacillus altitudinis strain CHB19]
MTTPKMDPKLLDSIIMKMLSTVDGSKDEVFRIGEQSRQQYESLVEELKQIKQQVNEVIDFGDKLEVHTRHARNRLSEVSR
NFNKFSEEEIREAYEKAHNLQVELTMIQQREKQLRERRDDLERRLLSLQDVIERSETLVSQITVVLNYLNQDLRQVGVLL
EDAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEEGFKEIRSLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLNTIEEYDGKTKITFQCLGDTENERIASQFEVALFRLAQEAVTNSLKHSEAEEISVKVEV
TKDFVTLIIKDDGKGFDMKDVKTNKNKSFGLLGMKERVDLLEGKMTIDSKIGLGTFIMIRVPLTLQNKIVK

Nucleotide

• Length: 1176 bp

>NTDB_id=385135 EVS87_RS16830 WP_024719243.1 3219113..3220288(-) (degS) [Bacillus altitudinis strain CHB19]
ATGACAACACCTAAAATGGATCCGAAGTTATTGGATTCAATCATCATGAAAATGCTAAGTACAGTTGATGGCAGTAAGGA
CGAAGTATTTAGAATCGGCGAACAGTCCCGTCAACAATATGAAAGCCTAGTAGAAGAGCTCAAGCAAATTAAACAGCAAG
TCAACGAAGTAATTGATTTTGGGGATAAACTAGAAGTACATACGAGACATGCTAGAAATCGATTATCTGAGGTCAGCAGA
AACTTCAACAAATTCAGCGAAGAAGAAATACGAGAAGCCTATGAAAAAGCACATAACCTGCAAGTAGAATTGACCATGAT
CCAGCAGCGCGAAAAACAGCTGAGGGAAAGAAGAGATGATCTCGAAAGACGATTGTTAAGCTTACAAGATGTCATTGAAC
GTTCAGAAACGCTTGTGAGCCAGATCACGGTCGTTCTCAACTACTTGAACCAAGATTTACGTCAGGTCGGTGTTTTACTT
GAAGATGCTCAGGCAAAACAAGATTTTGGACTAAGAATTATTGAAGCCCAGGAAGAAGAGCGCAAAAGGGTATCACGAGA
AATCCATGATGGACCTGCTCAGATGCTGGCAAACGTGATGATGCGTTCAGAACTAATTGAACGAATTTTTAGAGACCGTG
GAACAGAAGAAGGCTTTAAAGAAATTAGAAGTCTAAGACAGAATGTGCGAAATGCACTGTACGAAGTGAGAAGAATCATT
TATGATTTAAGACCGATGGCTTTAGATGATTTGGGTCTCATTCCGACACTGCGAAAATACTTAAACACAATTGAAGAATA
TGATGGAAAAACCAAAATTACGTTCCAATGCCTAGGGGATACAGAAAATGAAAGAATTGCTTCTCAGTTCGAAGTGGCAC
TGTTTAGACTAGCCCAAGAAGCTGTCACAAATTCATTGAAGCATTCCGAAGCTGAAGAAATCTCTGTAAAAGTAGAAGTG
ACAAAAGACTTTGTCACGTTAATTATCAAAGACGATGGAAAAGGCTTTGATATGAAAGATGTGAAAACAAATAAAAACAA
ATCCTTCGGTTTACTTGGCATGAAAGAGCGCGTAGACTTACTAGAAGGTAAAATGACCATAGACTCAAAAATAGGTCTAG
GGACATTTATCATGATTAGAGTACCGTTAACATTACAAAATAAAATTGTAAAATAG

Domains

Predicted by InterproScan.

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A0A081LEM4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	85.455	98.465	0.841