Detailed information NTG0385004

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: F0M21_RS16775
• Genome accession: NZ_CP043546
• Coordinates: 3377539..3378702 (-)
• Length: 387 a.a.
• NCBI ID: WP_007407484.1
• Uniprot ID: A3KLC1
• Organism: Bacillus velezensis strain SYP-B637
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3372539..3383702

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
F0M21_RS16745 (F0M21_16745)	-	3372804..3373223 (-)	420	WP_012118571.1	TIGR03826 family flagellar region protein	-
F0M21_RS16750 (F0M21_16750)	comFC	3373297..3373986 (-)	690	WP_197197403.1	phosphoribosyltransferase family protein	Machinery gene
F0M21_RS16755 (F0M21_16755)	-	3373992..3374276 (-)	285	WP_007407481.1	late competence development ComFB family protein	-
F0M21_RS16760 (F0M21_16760)	comFA	3374334..3375719 (-)	1386	WP_012118573.1	DEAD/DEAH box helicase	Machinery gene
F0M21_RS16765 (F0M21_16765)	-	3375827..3376675 (-)	849	WP_003151387.1	DegV family protein	-
F0M21_RS16770 (F0M21_16770)	degU	3376773..3377462 (-)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
F0M21_RS16775 (F0M21_16775)	degS	3377539..3378702 (-)	1164	WP_007407484.1	two-component sensor histidine kinase DegS	Regulator
F0M21_RS16780 (F0M21_16780)	-	3378925..3379572 (+)	648	WP_007614107.1	YigZ family protein	-
F0M21_RS16785 (F0M21_16785)	-	3379577..3380797 (+)	1221	WP_012118574.1	LCP family protein	-
F0M21_RS16790 (F0M21_16790)	-	3380896..3381972 (-)	1077	WP_003151382.1	glycosyltransferase family 4 protein	-
F0M21_RS16795 (F0M21_16795)	-	3382105..3383301 (-)	1197	WP_012118575.1	glycosyltransferase	-

Sequence

Protein

• Length: 387 a.a.
• Molecular weight: 45014.78 Da
• Isoelectric Point: 6.8616

>NTDB_id=385004 F0M21_RS16775 WP_007407484.1 3377539..3378702(-) (degS) [Bacillus velezensis strain SYP-B637]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide

• Length: 1164 bp

>NTDB_id=385004 F0M21_RS16775 WP_007407484.1 3377539..3378702(-) (degS) [Bacillus velezensis strain SYP-B637]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGCAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTCGAAGAACTTAAACAGATCAAACAGCAGG
TCTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCACGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAGTTCAGCGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAACAGCGTGAAAAGCAGCTGCGGGAGCGCAGGGATGATTTAGAACGCCGGCTTTTGGGGCTTCAGGAAATCATTGAAC
GGTCAGAATCATTGGTCAGCCAAATAACCGTCGTTCTGAATTACCTGAATCAAGACCTTCGCCAAGTAGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGTTTAAGAATCATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGACGGTCCCGCGCAAATGCTGGCAAATGTCATGATGAGATCGGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTGCGGCAGAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGACGATCTCGGGCTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGTATCGGAGACACGGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGTCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTA
ACCGCTGATTTTGTCGTTCTCATCATTAAGGACAACGGAAAAGGCTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
GTCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A3KLC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	95.584	99.483	0.951