Detailed information NTG0384832

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: MGAS2221_RS02345
• Genome accession: NZ_CP043530
• Coordinates: 438825..439826 (+)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A4U7H1B9
• Organism: Streptococcus pyogenes strain MGAS2221
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 433825..444826

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MGAS2221_RS02320 (MGAS2221_0464)	-	434499..435182 (-)	684	WP_002990714.1	DUF969 domain-containing protein	-
MGAS2221_RS02325 (MGAS2221_0465)	-	435393..436319 (-)	927	WP_002994177.1	glycosyltransferase family 2 protein	-
MGAS2221_RS02330 (MGAS2221_0466)	-	436464..436841 (-)	378	WP_002985686.1	VOC family protein	-
MGAS2221_RS02335 (MGAS2221_0467)	-	436852..437517 (-)	666	WP_010921982.1	NAD(P)H-dependent oxidoreductase	-
MGAS2221_RS02340 (MGAS2221_0468)	-	437566..438651 (-)	1086	WP_002985682.1	Xaa-Pro peptidase family protein	-
MGAS2221_RS02345 (MGAS2221_0469)	ccpA	438825..439826 (+)	1002	WP_002985680.1	catabolite control protein A	Regulator
MGAS2221_RS02350 (MGAS2221_0470)	-	439957..440955 (+)	999	WP_002985678.1	glycosyltransferase family 4 protein	-
MGAS2221_RS02355 (MGAS2221_0471)	-	440957..442291 (+)	1335	WP_002994187.1	glycosyltransferase family 4 protein	-
MGAS2221_RS02360 (MGAS2221_0472)	thrS	442713..444656 (+)	1944	WP_010921984.1	threonine--tRNA ligase	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=384832 MGAS2221_RS02345 WP_002985680.1 438825..439826(+) (ccpA) [Streptococcus pyogenes strain MGAS2221]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=384832 MGAS2221_RS02345 WP_002985680.1 438825..439826(+) (ccpA) [Streptococcus pyogenes strain MGAS2221]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
CAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAGTTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAACGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGTTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGCCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCGGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACCAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4U7H1B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559