Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   FY406_RS05700 Genome accession   NZ_CP043405
Coordinates   1149705..1151006 (+) Length   433 a.a.
NCBI ID   WP_003086453.1    Uniprot ID   A0A7X9QG16
Organism   Streptococcus ratti strain ATCC 31377     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1144705..1156006
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FY406_RS05675 (FY406_05675) - 1145332..1145973 (+) 642 WP_003086444.1 response regulator transcription factor -
  FY406_RS05680 (FY406_05680) - 1146017..1147429 (+) 1413 WP_003086446.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  FY406_RS05685 (FY406_05685) - 1147416..1147793 (+) 378 WP_003086447.1 S1 RNA-binding domain-containing protein -
  FY406_RS05690 (FY406_05690) cysK 1147983..1148909 (-) 927 WP_003086449.1 cysteine synthase A -
  FY406_RS05695 (FY406_05695) - 1149004..1149633 (-) 630 WP_003086451.1 YigZ family protein -
  FY406_RS05700 (FY406_05700) comFA/cflA 1149705..1151006 (+) 1302 WP_003086453.1 DEAD/DEAH box helicase Machinery gene
  FY406_RS05705 (FY406_05705) - 1151003..1151665 (+) 663 WP_003086455.1 ComF family protein -
  FY406_RS05710 (FY406_05710) hpf 1151750..1152298 (+) 549 WP_003086457.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  FY406_RS05715 (FY406_05715) - 1152582..1153676 (+) 1095 WP_003086460.1 hypothetical protein -
  FY406_RS05720 (FY406_05720) - 1153692..1155389 (+) 1698 WP_003086462.1 zinc ribbon domain-containing protein -

Sequence

Protein


Download         Length: 433 a.a.        Molecular weight: 49537.39 Da        Isoelectric Point: 9.9539

>NTDB_id=383586 FY406_RS05700 WP_003086453.1 1149705..1151006(+) (comFA/cflA) [Streptococcus ratti strain ATCC 31377]
MEDLKNYYGRLWTESQLNDSLKKHAQSMPAMTEKFPYFICNRCGSKNSSENALPDGSVYCRGCLVFGRISSREKLFYFEQ
QVFPEIQALSWQGQLTSFQQAVSDSLRKAVKNKEDILVHAVTGAGKTEMIYKTLDDILRQGKAAALVSPRVDVCLELYKR
LSRDFSCSISLLHAQSEAYERSPLVIATTHQLLRFYQAFDLLIVDEVDAFPFVDNKMLHYALNRCLKSDGVKVYLTATST
DKLDRQIKQGKLKQLHLARRFHAKPLVVPQSVWLNFSLEKLGQQKLPVRFLRYIRNQRQSRFPLLIFFPHIELGTLFAEA
LKKYFPDESIDFVSSLSPDRLEKVDGFRNGQIQILVSTTILERGVTFPNIDVFVMMANHRLFTKTALIQIAGRVGRSADR
PTGALIFFHNGLNKAIKTAVFEIKEMNRRGGFI

Nucleotide


Download         Length: 1302 bp        

>NTDB_id=383586 FY406_RS05700 WP_003086453.1 1149705..1151006(+) (comFA/cflA) [Streptococcus ratti strain ATCC 31377]
ATGGAGGACTTAAAAAATTATTATGGACGTTTGTGGACAGAGAGCCAATTAAATGACAGTTTGAAAAAGCATGCCCAAAG
TATGCCAGCTATGACAGAGAAATTCCCTTATTTTATCTGCAATCGCTGCGGCAGCAAAAACAGCTCCGAAAACGCTCTGC
CTGATGGTTCTGTTTACTGCCGAGGCTGTCTGGTCTTTGGCCGGATTAGCAGCCGAGAAAAACTGTTTTACTTTGAGCAG
CAGGTATTCCCTGAAATTCAGGCCTTGAGTTGGCAGGGGCAGCTGACTTCTTTTCAGCAGGCTGTTTCAGACAGTCTCAG
AAAAGCTGTCAAAAATAAAGAAGACATACTTGTTCACGCCGTTACTGGAGCCGGAAAGACTGAAATGATTTACAAGACTT
TGGATGATATTCTCAGGCAGGGGAAAGCAGCTGCACTGGTCAGCCCTCGGGTTGATGTTTGCTTGGAGCTGTATAAACGC
TTAAGCCGTGATTTTTCCTGCTCTATCAGTTTGCTCCATGCTCAATCAGAAGCTTATGAACGCAGTCCCTTAGTGATTGC
GACTACTCACCAGCTTTTAAGATTTTATCAGGCTTTCGATCTTTTAATTGTAGATGAAGTTGATGCTTTTCCTTTTGTTG
ATAATAAAATGCTGCACTATGCTTTAAATCGCTGCCTTAAATCTGATGGAGTCAAGGTGTATTTAACAGCAACTTCAACC
GATAAGCTGGACAGGCAAATCAAGCAGGGTAAGTTAAAACAGCTGCACTTAGCCAGACGTTTTCACGCTAAACCCTTGGT
TGTGCCCCAGAGTGTTTGGCTGAATTTTTCTTTGGAAAAATTAGGCCAGCAAAAACTGCCAGTTCGTTTTTTAAGGTATA
TTCGAAATCAGCGGCAGAGCCGCTTCCCTCTGCTGATTTTCTTTCCGCATATAGAATTGGGGACACTTTTTGCAGAGGCT
CTGAAAAAATATTTTCCGGACGAATCTATTGATTTTGTTTCTAGTTTAAGTCCGGATCGCTTAGAAAAGGTTGATGGATT
CAGAAACGGTCAGATTCAAATTTTAGTGTCAACAACTATTTTAGAAAGAGGCGTCACCTTTCCAAATATTGATGTTTTTG
TCATGATGGCTAATCACCGTTTATTCACCAAGACGGCCTTGATACAAATTGCCGGCCGGGTCGGGCGCTCAGCAGACCGG
CCGACAGGAGCCTTGATTTTCTTTCATAATGGTCTTAATAAGGCAATAAAAACAGCTGTTTTCGAGATTAAAGAAATGAA
TCGAAGGGGAGGCTTTATATGA

Domains

Predicted by InterproScan.

DEAD/DEAH box helicase (DEAD)

(107-240)

Helicase conserved C-terminal domain (Helicase_C)

(296-397)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7X9QG16

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus mitis SK321

55.269

98.614

0.545
  comFA/cflA Streptococcus pneumoniae D39

54.567

98.614

0.538
  comFA/cflA Streptococcus pneumoniae R6

54.567

98.614

0.538
  comFA/cflA Streptococcus mitis NCTC 12261

54.567

98.614

0.538
  comFA/cflA Streptococcus pneumoniae Rx1

54.567

98.614

0.538
  comFA/cflA Streptococcus pneumoniae TIGR4

54.333

98.614

0.536
  comFA Lactococcus lactis subsp. cremoris KW2

51.269

90.993

0.467
  comFA Latilactobacillus sakei subsp. sakei 23K

39.726

100

0.402

Multiple sequence alignment