Detailed information NTG0038320

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: SP670_RS10465
• Genome accession: NC_014498
• Coordinates: 1939479..1940489 (-)
• Length: 336 a.a.
• NCBI ID: WP_000990607.1
• Uniprot ID: A0A0B7LZL8
• Organism: Streptococcus pneumoniae 670-6B
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 1934479..1945489

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SP670_RS10440 (SP670_2073)	-	1935645..1935938 (-)	294	WP_000977371.1	hypothetical protein	-
SP670_RS10445 (SP670_2074)	-	1936100..1936552 (+)	453	WP_000079148.1	universal stress protein	-
SP670_RS10450 (SP670_2075)	-	1936587..1937975 (-)	1389	WP_000453137.1	Cof-type HAD-IIB family hydrolase	-
SP670_RS10455 (SP670_2076)	-	1938041..1939003 (+)	963	WP_001124777.1	asparaginase	-
SP670_RS10460 (SP670_2077)	-	1939032..1939415 (-)	384	WP_013315460.1	hypothetical protein	-
SP670_RS10465 (SP670_2078)	ccpA	1939479..1940489 (-)	1011	WP_000990607.1	catabolite control protein A	Regulator
SP670_RS10470 (SP670_2079)	-	1940915..1941514 (-)	600	WP_000772072.1	response regulator transcription factor	-
SP670_RS10475 (SP670_2080)	-	1941516..1942613 (-)	1098	WP_000893545.1	sensor histidine kinase	-
SP670_RS10480 (SP670_2081)	-	1942613..1943350 (-)	738	WP_000832844.1	ABC transporter permease	-
SP670_RS10485 (SP670_2082)	-	1943352..1944236 (-)	885	WP_000219348.1	ABC transporter ATP-binding protein	-
SP670_RS10490 (SP670_2083)	-	1944223..1944417 (-)	195	WP_000820178.1	hypothetical protein	-
SP670_RS10495 (SP670_2084)	-	1944414..1944620 (-)	207	WP_000503437.1	hypothetical protein	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37073.01 Da
• Isoelectric Point: 5.3212

>NTDB_id=38320 SP670_RS10465 WP_000990607.1 1939479..1940489(-) (ccpA) [Streptococcus pneumoniae 670-6B]
MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
SLAKGIDDIAEMYKYNIVLANSDEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGLVFESKYSYDDGYALAERLISSN
ATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSDDSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERSSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=38320 SP670_RS10465 WP_000990607.1 1939479..1940489(-) (ccpA) [Streptococcus pneumoniae 670-6B]
ATGAATGCAGATGATACAGTAACCATTTATGATGTCGCTCGTGAAGCAGGTGTTTCCATGGCGACGGTCAGCCGTGTGGT
CAATGGCAATAAAAATGTAAAAGAGAATACCCGTAAAAAAGTGCTAGAGGTAATTGATCGTTTGGATTATCGTCCAAATG
CAGTTGCGCGTGGTCTTGCAAGTAAAAAGACAACCACTGTCGGTGTCGTGATTCCAAATATTACCAATGGTTATTTTTCG
AGTTTGGCTAAGGGGATTGATGATATTGCAGAAATGTACAAGTACAATATTGTCCTAGCTAATAGCGATGAAGATAACGA
GAAAGAAGTTTCTGTTGTCAATACCCTCTTTTCAAAGCAGGTAGATGGCATTATCTATATGGGTTATCACTTGACAGATA
AAATTCGCTCAGAATTTTCGCGTTCACGTACTCCGATTGTTCTCGCAGGAACTGTCGATGTTGAGCACCAGTTGCCAAGT
GTCAATATTGACTATAAGCAAGCAACAATTGATGCAGTGAGTTACCTTGCTAAAGAAAATGAGCGTATTGCTTTCGTTAG
CGGTCCGCTAGTGGATGACATCAATGGTAAGGTTCGTTTAGTTGGCTACAAGGAAACCTTGAAAAAAGCAGGAATCACTT
ATAGTGAGGGTTTGGTATTTGAATCTAAATATAGCTATGATGATGGTTACGCCTTAGCAGAGCGTTTGATTTCATCAAAT
GCAACTGCAGCAGTTGTGACAGGTGATGAGTTGGCAGCAGGAGTCTTGAACGGTTTGGCTGATAAGGGTGTTTCTGTGCC
AGAAGATTTTGAAATTATTACTAGTGATGATTCACAAATCTCACGCTTTACCCGTCCAAACTTGACAACGATTGCCCAAC
CTCTTTATGACCTTGGTGCCATTAGTATGCGTATGTTGACCAAGATTATGCATAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTACCTCATGGTTTGACAGAACGTAGCTCAACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (181-332)

3D structure

• AlphaFold DB: A0A0B7LZL8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	99.702	100	0.997
ccpA	Streptococcus gordonii str. Challis substr. CH1	87.126	99.405	0.866
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	57.704	98.512	0.568