Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilA   Type   Machinery gene
Locus tag   FXN57_RS01040 Genome accession   NZ_CP043005
Coordinates   211679..212131 (+) Length   150 a.a.
NCBI ID   WP_148323376.1    Uniprot ID   -
Organism   Aggregatibacter actinomycetemcomitans strain PN_696     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 206679..217131
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FXN57_RS01025 (FXN57_01025) pnp 207637..209766 (-) 2130 WP_148323370.1 polyribonucleotide nucleotidyltransferase -
  FXN57_RS01030 (FXN57_01030) nanQ 210059..210529 (+) 471 WP_148323372.1 N-acetylneuraminate anomerase -
  FXN57_RS01035 (FXN57_01035) ampD 211003..211557 (-) 555 WP_148323374.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  FXN57_RS01040 (FXN57_01040) pilA 211679..212131 (+) 453 WP_148323376.1 prepilin-type N-terminal cleavage/methylation domain-containing protein Machinery gene
  FXN57_RS01045 (FXN57_01045) - 212158..212982 (+) 825 Protein_203 GspE/PulE family protein -
  FXN57_RS01060 (FXN57_01060) - 213603..213863 (-) 261 WP_148323380.1 DNA-binding protein -
  FXN57_RS01065 (FXN57_01065) - 214053..214265 (+) 213 WP_032996596.1 helix-turn-helix domain-containing protein -
  FXN57_RS01070 (FXN57_01070) - 214281..214727 (+) 447 WP_262404684.1 DNA-binding protein -
  FXN57_RS01075 (FXN57_01075) - 214711..215130 (+) 420 Protein_207 putative quinol monooxygenase -
  FXN57_RS01080 (FXN57_01080) secE 215567..215977 (+) 411 WP_148327417.1 preprotein translocase subunit SecE -
  FXN57_RS01085 (FXN57_01085) nusG 215979..216530 (+) 552 WP_005547787.1 transcription termination/antitermination protein NusG -
  FXN57_RS01090 (FXN57_01090) rplK 216687..217115 (+) 429 WP_148323384.1 50S ribosomal protein L11 -

Sequence

Protein


Download         Length: 150 a.a.        Molecular weight: 15591.97 Da        Isoelectric Point: 8.8052

>NTDB_id=380154 FXN57_RS01040 WP_148323376.1 211679..212131(+) (pilA) [Aggregatibacter actinomycetemcomitans strain PN_696]
MKIQSAFISLKFVKKGFTLIELMIVIAIVAILATVAVPSYQNYTKKAAVSELLQASAPLRSEVELCIYNTGKAENCSGGQ
NGIQADVADASKQKYVKSTAVKGGAITVTGKGSLDKISYTLTASDTAATGVSWNAACGNNADIFPAGFCS

Nucleotide


Download         Length: 453 bp        

>NTDB_id=380154 FXN57_RS01040 WP_148323376.1 211679..212131(+) (pilA) [Aggregatibacter actinomycetemcomitans strain PN_696]
ATGAAAATTCAATCCGCGTTTATTTCGCTAAAATTCGTTAAAAAAGGGTTTACATTAATCGAATTAATGATCGTCATAGC
TATCGTTGCTATTCTCGCCACCGTAGCCGTGCCATCTTATCAAAATTATACCAAAAAAGCGGCGGTTTCCGAATTATTAC
AAGCCTCCGCGCCATTACGTTCCGAAGTGGAACTCTGTATTTATAACACCGGTAAGGCTGAAAATTGTAGCGGCGGACAA
AATGGCATTCAAGCAGATGTTGCGGATGCTTCGAAACAAAAATATGTGAAATCCACCGCGGTCAAGGGTGGTGCGATCAC
TGTTACCGGCAAAGGCAGTTTGGATAAAATCAGCTACACCCTTACCGCTTCGGACACAGCTGCCACCGGGGTCAGCTGGA
ACGCCGCCTGCGGCAATAATGCCGACATTTTCCCGGCAGGTTTCTGTTCTTAA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(14-36)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilA Haemophilus influenzae 86-028NP

63.043

92

0.58
  pilA Haemophilus influenzae Rd KW20

58.333

96

0.56
  pilA Glaesserella parasuis strain SC1401

53.147

95.333

0.507

Multiple sequence alignment