Detailed information NTG0377554

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: HA248_RS09670
• Genome accession: NZ_CP050175
• Coordinates: 1863524..1864423 (-)
• Length: 299 a.a.
• NCBI ID: WP_000904834.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain PZ900701590
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 1858524..1869423

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HA248_RS09645 (HA248_09625)	rsmA	1858749..1859621 (-)	873	WP_001216856.1	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA	-
HA248_RS11625	-	1859872..1860165 (-)	294	Protein_1883	hypothetical protein	-
HA248_RS09655 (HA248_09635)	-	1860158..1860799 (-)	642	WP_000565531.1	ABC transporter ATP-binding protein	-
HA248_RS09660 (HA248_09640)	-	1860801..1862831 (-)	2031	WP_033705592.1	bacteriocin-associated integral membrane family protein	-
HA248_RS09665 (HA248_09645)	-	1862908..1863204 (-)	297	WP_000815392.1	lactococcin 972 family bacteriocin	-
HA248_RS09670 (HA248_09650)	comR	1863524..1864423 (-)	900	WP_000904834.1	helix-turn-helix transcriptional regulator	Regulator
HA248_RS09675 (HA248_09655)	rnmV	1864495..1865055 (-)	561	WP_000664448.1	ribonuclease M5	-
HA248_RS09680 (HA248_09660)	-	1865055..1865828 (-)	774	WP_000575600.1	TatD family hydrolase	-
HA248_RS09685 (HA248_09665)	-	1866133..1867026 (-)	894	WP_000226476.1	cell wall surface anchor protein	-
HA248_RS09690 (HA248_09670)	rpmH	1867310..1867444 (-)	135	WP_000831905.1	50S ribosomal protein L34	-
HA248_RS09695 (HA248_09675)	-	1867589..1868803 (-)	1215	WP_000666469.1	pyridoxal phosphate-dependent aminotransferase	-
HA248_RS09700 (HA248_09680)	-	1868959..1869252 (-)	294	WP_000977371.1	hypothetical protein	-

Sequence

Protein

• Length: 299 a.a.
• Molecular weight: 35263.10 Da
• Isoelectric Point: 4.9762

>NTDB_id=377554 HA248_RS09670 WP_000904834.1 1863524..1864423(-) (comR) [Streptococcus pneumoniae strain PZ900701590]
MLIGQKIKEIRIEKGISRPDFCGDEQELTVRQLSRIESGASQPSLPKLAYIARRLGVPVYSLMPDFSALPSAYLELKYQI
LREPIYGKEEEYDKKEACLEEIYKTYFDNLPKEEQLACEVLQACLDTSRTRRPEYAELILEEHMPQIIEKEAYSINDMLL
IRLFFYQMLIRKDLAKFINQIEKLMLFLLEQKKVTQIENYFIIRDTLISGMCCLEKVGVTDCFNDYLSCLQEIMDKTQDY
QKKPLVFMFLWKQALRVERDFSLAESFYQSSKTFAKLIGDGFLVKKLTEEWQEDVKKYL

Nucleotide

• Length: 900 bp

>NTDB_id=377554 HA248_RS09670 WP_000904834.1 1863524..1864423(-) (comR) [Streptococcus pneumoniae strain PZ900701590]
ATGTTAATTGGTCAAAAAATTAAAGAGATTCGGATAGAAAAAGGAATTAGTCGTCCAGATTTTTGTGGAGATGAGCAAGA
ACTGACAGTTCGTCAACTGTCGCGAATTGAAAGTGGAGCTTCGCAACCGAGTTTGCCCAAGTTAGCCTATATTGCTCGCC
GGCTAGGAGTTCCAGTTTATAGCCTTATGCCGGATTTTTCAGCTCTTCCTTCTGCTTATTTAGAATTGAAATACCAGATT
TTACGTGAACCAATCTATGGTAAAGAAGAGGAGTACGATAAGAAGGAAGCGTGTTTGGAAGAGATTTATAAAACATACTT
TGATAATCTTCCTAAAGAAGAACAATTAGCATGTGAAGTATTGCAGGCGTGTTTGGATACTTCTAGAACTAGAAGGCCTG
AATATGCAGAGTTAATACTTGAGGAACATATGCCTCAGATTATAGAAAAAGAAGCTTATTCAATAAATGATATGTTGTTG
ATTCGTTTGTTTTTTTATCAAATGCTCATTAGAAAAGATCTTGCCAAATTTATAAATCAAATCGAAAAGCTAATGCTCTT
TCTTTTGGAACAGAAGAAGGTAACTCAAATAGAGAATTACTTTATAATTAGAGATACTCTTATTTCAGGAATGTGTTGTC
TTGAAAAGGTAGGAGTAACTGATTGTTTTAATGATTATCTATCGTGTTTACAAGAAATTATGGATAAAACTCAAGATTAT
CAAAAGAAACCTCTTGTATTTATGTTTTTGTGGAAGCAAGCATTAAGAGTAGAAAGAGATTTTAGTTTAGCTGAATCATT
TTATCAGTCTTCTAAAACATTTGCGAAGCTAATTGGAGATGGATTTCTAGTAAAGAAATTGACAGAGGAATGGCAAGAGG
ATGTCAAAAAATATTTATAA

Domains

Predicted by InterProScan.

• ComR tetratricopeptide (ComR_TPR) (70-291)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus mutans UA159	37.755	98.328	0.371
comR	Streptococcus suis P1/7	38.144	97.324	0.371
comR	Streptococcus suis 05ZYH33	38.144	97.324	0.371
comR	Streptococcus suis D9	36.12	100	0.361