Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   G9P51_RS03675 Genome accession   NZ_CP050044
Coordinates   774431..775090 (-) Length   219 a.a.
NCBI ID   WP_130553695.1    Uniprot ID   -
Organism   Escherichia coli strain 74-2     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 769431..780090
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  G9P51_RS03650 (G9P51_03665) parE 769522..771414 (+) 1893 WP_000195296.1 DNA topoisomerase IV subunit B -
  G9P51_RS03655 (G9P51_03670) ygiN 771462..771776 (-) 315 WP_000958598.1 putative quinol monooxygenase -
  G9P51_RS03660 (G9P51_03675) mdaB 771807..772388 (-) 582 WP_000065430.1 NADPH:quinone oxidoreductase MdaB -
  G9P51_RS03665 (G9P51_03680) ygiZ 772707..773039 (+) 333 WP_000917684.1 DUF2645 family protein -
  G9P51_RS03670 (G9P51_03685) qseC 773085..774434 (-) 1350 WP_000673402.1 quorum sensing histidine kinase QseC -
  G9P51_RS03675 (G9P51_03690) ciaR 774431..775090 (-) 660 WP_130553695.1 quorum sensing response regulator transcription factor QseB Regulator
  G9P51_RS03680 (G9P51_03695) - 775316..776284 (+) 969 WP_000654811.1 IS5 family transposase -
  G9P51_RS03685 (G9P51_03700) mqsR 776520..776816 (+) 297 WP_000415584.1 type II toxin-antitoxin system toxin MqsR -
  G9P51_RS03690 (G9P51_03705) mqsA 776818..777213 (+) 396 WP_130553696.1 type II toxin-antitoxin system antitoxin MqsA -
  G9P51_RS03695 (G9P51_03710) ygiS 777346..778953 (+) 1608 Protein_735 ABC transporter substrate-binding protein -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24701.65 Da        Isoelectric Point: 6.9850

>NTDB_id=376307 G9P51_RS03675 WP_130553695.1 774431..775090(-) (ciaR) [Escherichia coli strain 74-2]
MRILLIEDDMLIGDGIKTGLSKMGFSVDWFTQGRQGKEALYSAPYDAVILDLTLPGMDGRDILREWREKGQREPVLILTA
RDALAERVEGLRLGADDYLCKPFALIEIAARLEALMRRTNGQASNELRHGNVMLDPGKRIATLAGEPLTLKPKEFALLEL
LMRNAGRVLPRKLIEEKLYTWDEEVTSNAVEVHVHHLRRKLGSDFIRTVHGIGYTLGEK

Nucleotide


Download         Length: 660 bp        

>NTDB_id=376307 G9P51_RS03675 WP_130553695.1 774431..775090(-) (ciaR) [Escherichia coli strain 74-2]
ATGCGAATTTTACTGATAGAAGATGACATGCTGATTGGCGACGGCATCAAAACGGGCCTTAGTAAAATGGGTTTTAGCGT
CGACTGGTTTACACAAGGTCGTCAGGGAAAAGAGGCGCTTTATAGCGCACCTTATGATGCGGTGATCCTGGATTTAACCT
TACCAGGCATGGATGGTCGCGATATTTTGCGCGAATGGCGAGAAAAAGGTCAGCGTGAGCCGGTACTGATCCTGACCGCG
CGCGATGCGCTGGCGGAACGTGTAGAAGGGCTGCGTCTGGGAGCTGACGATTATCTGTGTAAACCTTTTGCGTTGATAGA
AATCGCCGCCAGGCTGGAAGCTCTGATGCGCCGAACCAACGGCCAGGCCAGCAACGAGCTGCGCCACGGTAACGTCATGC
TCGACCCCGGCAAACGTATCGCCACGCTGGCTGGCGAACCCTTAACACTGAAACCAAAAGAATTTGCCCTGCTGGAATTA
CTGATGCGTAACGCTGGTCGGGTACTGCCGCGCAAACTGATTGAAGAGAAACTGTATACCTGGGACGAAGAGGTCACCAG
TAATGCCGTTGAAGTGCATGTGCATCATCTGCGACGCAAACTCGGTAGTGATTTTATTCGTACCGTGCATGGTATTGGTT
ACACATTAGGTGAGAAATGA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-216)

Response regulator receiver domain (Response_reg)

(3-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

38.326

100

0.397
  ciaR Streptococcus pneumoniae D39

38.326

100

0.397
  ciaR Streptococcus pneumoniae R6

38.326

100

0.397
  ciaR Streptococcus pneumoniae TIGR4

38.326

100

0.397
  ciaR Streptococcus mutans UA159

35.874

100

0.365

Multiple sequence alignment